Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Yasushi, Hirota"'
Autor:
Shizu Aikawa, Takehiro Hiraoka, Mitsunori Matsuo, Yamato Fukui, Hidetoshi Fujita, Tomoko Saito-Fujita, Ryoko Shimizu-Hirota, Norihiko Takeda, Daiki Hiratsuka, Xueting He, Chihiro Ishizawa, Rei Iida, Shun Akaeda, Miyuki Harada, Osamu Wada-Hiraike, Masahito Ikawa, Yutaka Osuga, Yasushi Hirota
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Embryo implantation is crucial for successful pregnancy, requiring appropriate uterine responses to implantation-competent blastocysts. Molecular communication at the maternal–fetal junction governs this process. Leukemia inhibitory factor
Externí odkaz:
https://doaj.org/article/44070a8a25c241808ffe0e26a0f15b48
Autor:
Yoshihide Yamanashi, Toko Komine, Yasushi Hirota, Hiroshi Suzuki, Yutaka Osuga, Tappei Takada
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Dietary modifications to overcome infertility have attracted attention; however, scientifically substantiated information on specific dietary components affecting fertility and their mechanisms is limited. Herein, we investigated diet-induce
Externí odkaz:
https://doaj.org/article/a54b997ad782490fae0e0dbafafe04e9
Autor:
Ryosuke Kobayashi, Yuki Tajika, Junki Kohmaru, Sumiyo Morita, Takuro Horii, Yoichi Mizukami, Shizu Aikawa, Yasushi Hirota, Izuho Hatada
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Embryo implantation failures are a major challenge in reproductive medicine, but the underlying mechanism remains poorly understood. Successful implantation requires dynamic remodeling of the endometrium through integrated proliferation and
Externí odkaz:
https://doaj.org/article/e712b2ec98b54d358ea32e9c927671eb
Autor:
Risa Sakamoto, Takuji Fujiwara, Yuko Kawano, Shizu Aikawa, Tomoaki Inazumi, On Nakayama, Yukiko Kawasaki-Shirata, Miho Hashimoto-Iwasaki, Toshiko Sugimoto, Soken Tsuchiya, Satohiro Nakao, Toru Takeo, Yasushi Hirota, Yukihiko Sugimoto
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 10, Pp 100636- (2024)
To investigate the yet-unknown roles of prostaglandins (PGs) in the uterus, we analyzed the expression of various PG receptors in the uterus. We found that three types of Gs-coupled PG receptors, DP, EP2, and EP4, were expressed in luminal epithelial
Externí odkaz:
https://doaj.org/article/4348ced3604448f3a4a4d76898ea9b70
Autor:
Daiki Hiratsuka, Erika Omura, Chihiro Ishizawa, Rei Iida, Yamato Fukui, Takehiro Hiraoka, Shun Akaeda, Mitsunori Matsuo, Miyuki Harada, Osamu Wada-Hiraike, Yutaka Osuga, Yasushi Hirota
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Adenomyosis is a common gynecological disease in women of reproductive age and causes various symptoms such as dysmenorrhea and heavy menstrual bleeding. However, the influence of pregnancy on the progression of adenomyosis remain
Externí odkaz:
https://doaj.org/article/47e8b6d7a8c14c978564ccec2f43071b
Autor:
Akari Kusamoto, Miyuki Harada, Ayaka Minemura, Asami Matsumoto, Kentaro Oka, Motomichi Takahashi, Nanoka Sakaguchi, Jerilee M. K. Azhary, Hiroshi Koike, Zixin Xu, Tsurugi Tanaka, Yoko Urata, Chisato Kunitomi, Nozomi Takahashi, Osamu Wada-Hiraike, Yasushi Hirota, Yutaka Osuga
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The gut microbiome is implicated in the pathogenesis of polycystic ovary syndrome (PCOS), and prenatal androgen exposure is involved in the development of PCOS in later life. Our previous study of a mouse model of PCOS induced by prenatal dihydrotest
Externí odkaz:
https://doaj.org/article/90b5c734052349d09fdd929a2b8053ed
Autor:
Yamato Fukui, Yasushi Hirota, Shizu Aikawa, Akihiko Sakashita, Ryoko Shimizu-Hirota, Norihiko Takeda, Chihiro Ishizawa, Rei Iida, Tetsuaki Kaku, Tomoyuki Hirata, Takehiro Hiraoka, Shun Akaeda, Mitsunori Matsuo, Yutaka Osuga
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-12 (2023)
Abstract Infertility occurs in 15% of couples worldwide. Recurrent implantation failure (RIF) is one of the major problems in in vitro fertilization and embryo transfer (IVF–ET) programs, and how to manage patients with RIF to achieve successful pr
Externí odkaz:
https://doaj.org/article/7a6eca6a7f744b3f90823466c14b402e
Autor:
Seisuke Sayama, MD, PhD, Takayuki Iriyama, MD, PhD, Ayako Hashimoto, MD, PhD, Kensuke Suzuki, MD, PhD, Yu Ariyoshi, MD, Eriko Yano, MD, Masatake Toshimitsu, MD, PhD, Mari Ichinose, MD, PhD, Takahiro Seyama, MD, PhD, Kenbun Sone, MD, PhD, Keiichi Kumasawa, MD, PhD, Yasushi Hirota, MD, PhD, Yutaka Osuga, MD, PhD
Publikováno v:
AJOG Global Reports, Vol 3, Iss 4, Pp 100265- (2023)
BACKGROUND: Adenomyosis is associated with unfavorable perinatal outcomes; however, the effect of an adenomyomectomy on pregnancy outcomes remains unclear. Pregnancy following an adenomyomectomy has been reported to be associated with a high risk for
Externí odkaz:
https://doaj.org/article/957de82ca60447b18f0fa5f26fc50e71
Autor:
Mohammed Elsherbini, Kaori Koga, Takehiro Hiraoka, Keiichi Kumasawa, Eiko Maki, Erina Satake, Ayumi Taguchi, Tomoko Makabe, Arisa Takeuchi, Gentaro Izumi, Masashi Takamura, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Osamu Wada-Hiraike, Yutaka Osuga
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The purpose of this study was to establish a novel mouse model of adenomyosis suitable for longitudinal and quantitative analyses and perinatal outcome studies. Using a 30 G needle, the entire uterine wall of one horn was mechanically punctu
Externí odkaz:
https://doaj.org/article/37cb6498a3614e028cf371159135ffbc
Autor:
Nozomi Takahashi, Miyuki Harada, Mayuko Kanatani, Osamu Wada-Hiraike, Yasushi Hirota, Yutaka Osuga
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 651 (2024)
It is unclear whether clinical background differs between endometriosis in adolescent patients with obstructive Müllerian anomalies and those without anomalies. The aim of the study is to identify the difference in clinical characteristics of endome
Externí odkaz:
https://doaj.org/article/699c7a64b6664c22b09803d282bbdb73