Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Yasuro Shinohara"'
Autor:
Motoi Kanagawa, Kazuhiro Kobayashi, Michiko Tajiri, Hiroshi Manya, Atsushi Kuga, Yoshiki Yamaguchi, Keiko Akasaka-Manya, Jun-ichi Furukawa, Mamoru Mizuno, Hiroko Kawakami, Yasuro Shinohara, Yoshinao Wada, Tamao Endo, Tatsushi Toda
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2209-2223 (2016)
Glycosylation is an essential post-translational modification that underlies many biological processes and diseases. α-dystroglycan (α-DG) is a receptor for matrix and synaptic proteins that causes muscular dystrophy and lissencephaly upon its abno
Externí odkaz:
https://doaj.org/article/be3bb2e74f784761b334a8e2d70b74af
Autor:
Jun-ichi Furukawa, Shota Sakai, Ikuko Yokota, Kazue Okada, Hisatoshi Hanamatsu, Takashi Kobayashi, Yasunobu Yoshida, Kenichi Higashino, Tomohiro Tamura, Yasuyuki Igarashi, Yasuro Shinohara
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2399-2407 (2015)
Glycosphingolipids (GSLs) are lipid molecules linked to carbohydrate units that form the plasma membrane lipid raft, which is clustered with sphingolipids, sterols, and specific proteins, and thereby contributes to membrane physical properties and sp
Externí odkaz:
https://doaj.org/article/e1798022ae1543bb92ba70dd9dbf70f0
Autor:
Nobuaki Miura, Hisatoshi Hanamatsu, Ikuko Yokota, Kazue Okada, Jun-Ichi Furukawa, Yasuro Shinohara
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1383 (2020)
Glycans present extraordinary structural diversity commensurate with their involvement in numerous fundamental cellular processes including growth, differentiation, and morphogenesis. Unlike linear DNA and protein sequences, glycans have heterogeneou
Externí odkaz:
https://doaj.org/article/fc5114309a2240d8965f00b7e971252c
Publikováno v:
Biomolecules, Vol 3, Iss 1, Pp 198-225 (2013)
A large variety of glycans is intricately located on the cell surface, and the overall profile (the glycome, given the entire repertoire of glycoconjugate-associated sugars in cells and tissues) is believed to be crucial for the diverse roles of glyc
Externí odkaz:
https://doaj.org/article/70cb4c116a9743448d7091a5ace4ac63
Publikováno v:
Sensors, Vol 8, Iss 7, Pp 4282-4295 (2008)
Carcinoembryonic antigen (CEA) is an oncofoetal cell-surface glycoprotein that serves as an important tumor marker for colorectal and some other carcinomas. In this work, a CEA immunoassay using a surface plasmon resonance (SPR) biosensor has been de
Externí odkaz:
https://doaj.org/article/e49afce2a20745e8987ae1bd26ab530d
Autor:
Jun-ichi Furukawa, Masumi Tsuda, Kazue Okada, Taichi Kimura, Jinhua Piao, Shinya Tanaka, Yasuro Shinohara
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0128300 (2015)
Cancer cells frequently express glycans at different levels and/or with fundamentally different structures from those expressed by normal cells, and therefore elucidation and manipulation of these glycosylations may provide a beneficial approach to c
Externí odkaz:
https://doaj.org/article/e43fe306402b407eb549a02701f7a119
Autor:
Yukinori Tsukuda, Norimasa Iwasaki, Naoki Seito, Masashi Kanayama, Naoki Fujitani, Yasuro Shinohara, Yasuhiko Kasahara, Tomohiro Onodera, Koji Suzuki, Tsuyoshi Asano, Akio Minami, Tadashi Yamashita
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40136 (2012)
Rheumatoid arthritis (RA), a chronic systemic inflammatory disorder that principally attacks synovial joints, afflicts over 2 million people in the United States. Interleukin (IL)-17 is considered to be a master cytokine in chronic, destructive arthr
Externí odkaz:
https://doaj.org/article/6aab173efe144ece8d008720f3454c71
Autor:
Hiroki Yoshioka, Satoshi Yokota, Sarah Tominaga, Yosuke Tsukiboshi, Masumi Suzui, Yasuro Shinohara, Masae Yoshikawa, Hayato Sasaki, Nobuya Sasaki, Tohru Maeda, Nobuhiko Miura
Publikováno v:
Biological and Pharmaceutical Bulletin. 46:824-829
Publikováno v:
The Journal of Toxicological Sciences. 47:547-553
Autor:
Nobuaki Miura, Hisatoshi Hanamatsu, Ikuko Yokota, Keiko Akasaka-Manya, Hiroshi Manya, Tamao Endo, Yasuro Shinohara, Jun-ichi Furukawa
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13097
Glycans are involved in many fundamental cellular processes such as growth, differentiation, and morphogenesis. However, their broad structural diversity makes analysis difficult. Glycomics via mass spectrometry has focused on the composition of glyc