Zobrazeno 1 - 10
of 738
pro vyhledávání: '"Yasuo WATANABE"'
Autor:
Honami Echizen, Kenjiro Hanaoka, Kazuhito Shimamoto, Ryota Hibi, Sachiko Toma-Fukai, Hisashi Ohno, Eita Sasaki, Toru Komatsu, Tasuku Ueno, Yukihiro Tsuchiya, Yasuo Watanabe, Takao Otsuka, Hiroaki Saito, Satoru Nagatoishi, Kouhei Tsumoto, Hirotatsu Kojima, Takayoshi Okabe, Toshiyuki Shimizu, Yasuteru Urano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract D,L-Propargylglycine (PAG) has been widely used as a selective inhibitor to investigate the biological functions of cystathionine γ-lyase (CSE), which catalyzes the formation of reactive sulfur species (RSS). However, PAG also inhibits othe
Externí odkaz:
https://doaj.org/article/90eed93fe0d34640b472dbfd8bff78fa
Autor:
Ryoken Aoki, Yasuo Watanabe, Yuki Sakai, Megumi Furukawa, Takahiro Shigetomi, Chen Jiun Rong, Nobuo Izumo
Publikováno v:
Current Research in Food Science, Vol 8, Iss , Pp 100713- (2024)
Sparassis crispa, an edible mushroom, has been reported to show many kinds of physiological functions. The present paper focused on reducing body weight, subcutaneous fat, and visceral fat gain in ovariectomized (OVX) mice. Using the fruiting body po
Externí odkaz:
https://doaj.org/article/00a82981569044da8303cafcea2c4d66
Autor:
Koji Osuka, Yusuke Ohmichi, Mika Ohmichi, Satoru Honma, Chiharu Suzuki, Masahiro Aoyama, Kenichiro Iwami, Yasuo Watanabe, Shigeru Miyachi
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1440 (2023)
Background: A chronic subdural hematoma (CSDH) is considered to be an inflammatory and angiogenic disease. The CSDH outer membrane, which contains inflammatory cells, plays an important role in CSDH development. Osteopontin (OPN) is an extracellular
Externí odkaz:
https://doaj.org/article/64bc4b7fae374b4c8d32515e59852def
Autor:
Shotaro Kamata, Takuji Oyama, Kenta Saito, Akihiro Honda, Yume Yamamoto, Keisuke Suda, Ryo Ishikawa, Toshimasa Itoh, Yasuo Watanabe, Takahiro Shibata, Koji Uchida, Makoto Suematsu, Isao Ishii
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101727- (2020)
Summary: Most triacylglycerol-lowering fibrates have been developed in the 1960s–1980s before their molecular target, peroxisome proliferator-activated receptor alpha (PPARα), was identified. Twenty-one ligand-bound PPARα structures have been dep
Externí odkaz:
https://doaj.org/article/019e9a2e669140bd9f38f82355fbf354
Autor:
Koji Osuka, Yasuo Watanabe, Nobuteru Usuda, Kenichiro Iwami, Shigeru Miyachi, Masakazu Takayasu
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233643 (2020)
Chronic subdural hematoma (CSDH) is an angiogenic and inflammatory disease. Toll-like receptors (TLRs) transduce intracellular signals, resulting in the activation of nuclear factor κB (NF-κB), which leads to the production of inflammatory cytokine
Externí odkaz:
https://doaj.org/article/f021e897b5d645469916e2ac96233773
Autor:
Takaaki Akaike, Tomoaki Ida, Fan-Yan Wei, Motohiro Nishida, Yoshito Kumagai, Md. Morshedul Alam, Hideshi Ihara, Tomohiro Sawa, Tetsuro Matsunaga, Shingo Kasamatsu, Akiyuki Nishimura, Masanobu Morita, Kazuhito Tomizawa, Akira Nishimura, Satoshi Watanabe, Kenji Inaba, Hiroshi Shima, Nobuhiro Tanuma, Minkyung Jung, Shigemoto Fujii, Yasuo Watanabe, Masaki Ohmuraya, Péter Nagy, Martin Feelisch, Jon M. Fukuto, Hozumi Motohashi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cysteine hydropersulfides (CysSSH) are believed to have a cellular redox protective role. Here the authors show that these species can be produced from L-cysteine by cysteinyl-tRNA synthetases and that these enzymes are also involved in mitochondrial
Externí odkaz:
https://doaj.org/article/59355d393d744dc18b1812f57d180eae
Autor:
Takayuki Matsuno, Shota Toyoshima, Tomomi Sakamoto-Sasaki, Jun-ichi Kashiwakura, Akira Matsuda, Yasuo Watanabe, Hiromitsu Azuma, Kei Kawana, Tatsuo Yamamoto, Yoshimichi Okayama
Publikováno v:
Allergology International, Vol 67, Iss , Pp S18-S24 (2018)
Background: Although rodent decidual mast cells (MCs) reportedly play an important role in implantation and placenta formation, the characterization of human decidual MCs has been not well clarified. The aims of this study were to investigate the dis
Externí odkaz:
https://doaj.org/article/637b9344509a45938e0908c160ba275a
Publikováno v:
Biotechnology Reports, Vol 18, Iss C (2018)
The gene encoding the Saccharomyces cerevisiae phospholipid deacylation enzyme, phospholipase B (ScPLB1), was successfully expressed in E. coli. The enzyme (Scplb1p) was engineered to have a histidine-tag at the C-terminal end and was purified by met
Externí odkaz:
https://doaj.org/article/e156608408ac476f8891db54cf46cbc1
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 617-626 (2014)
l-Ornithine cyclodeaminase (OCD) is involved in l-proline biosynthesis and catalyzes the unique deaminating cyclization of l-ornithine to l-proline via a Δ1-pyrroline-2-carboxyrate (Pyr2C) intermediate. Although this pathway functions in only a few
Externí odkaz:
https://doaj.org/article/fc2c1c6d56be445ab44e5a39d0417dd6
Autor:
Seiya Watanabe, Yoshiaki Tanimoto, Seiji Yamauchi, Yuzuru Tozawa, Shigeki Sawayama, Yasuo Watanabe
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 240-250 (2014)
trans-4-Hydroxy-l-proline (T4LHyp) and trans-3-hydroxy-l-proline (T3LHyp) occur mainly in collagen. A few bacteria can convert T4LHyp to α-ketoglutarate, and we previously revealed a hypothetical pathway consisting of four enzymes at the molecular l
Externí odkaz:
https://doaj.org/article/2bcf459abe424206850897a564c511ab