Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Yasuo Kizawa"'
Autor:
Yuki Nishimoto, Daiki Ando, Kosuke Irie, Ikumi Kainuma, Yuki Katayama, Shiori Sato, Tomohiro Suzuki, Mai Harada, Tsubasa Yoshida, Kazuhiro Ito, Yasuo Kizawa
Publikováno v:
Biochemistry and Biophysics Reports, Vol 33, Iss , Pp 101402- (2023)
Asthma exacerbation is a significant clinical problem that causes resistance to corticosteroid therapy and elevated hospitalization risk. Src family kinases (SFKs) contribute to various steps of the immune response, such as airway inflammation in vir
Externí odkaz:
https://doaj.org/article/bc769493b78d48329e6372216d805cae
Autor:
Yuki Nishimoto, Daiki Ando, Kosuke Irie, Ikumi Kainuma, Yuki Katayama, Shiori Sato, Tomohiro Suzuki, Mai Harada, Tsubasa Yoshida, Kazuhiro Ito, Yasuo Kizawa
Publikováno v:
Biochemistry and biophysics reports. 33
Asthma exacerbation is a significant clinical problem that causes resistance to corticosteroid therapy and elevated hospitalization risk. Src family kinases (SFKs) contribute to various steps of the immune response, such as airway inflammation in vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0c06be7962b1f0d685a2dcbe675651
https://pubmed.ncbi.nlm.nih.gov/36478895
https://pubmed.ncbi.nlm.nih.gov/36478895
Autor:
Thomas Colley, Pete Strong, Genki Kimura, Yuki Nishimoto, Yasuo Kizawa, Leah Daly, Gurpreet Sehra, Garth Rapeport, Kazuhiro Ito, Takahiro Nakaoki
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a322f3d23c8befc314f0f01255a512
http://link.springer.com/article/10.1038/s41598-019-45890-w
http://link.springer.com/article/10.1038/s41598-019-45890-w
Autor:
Garth Rapeport, Jacques F. Meis, Yuki Nishimoto, Thomas Colley, Alexandre Alanio, Stéphane Bretagne, Kazuhiro Ito, Pete Strong, Anuradha Chowdhary, Genki Kimura, Leah Daly, Yasuo Kizawa, Cheshta Sharma, Takahiro Nakaoki
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives The growing emergence of azole-resistant Aspergillus fumigatus strains worldwide is a major concern for current systemic antifungal treatment. Here we report antifungal activities of a novel inhaled triazole, PC1244, against a collection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b3282e4fc5c706fe37474d652d4c54
http://europepmc.org/articles/PMC6753496
http://europepmc.org/articles/PMC6753496
Autor:
Nicolas Mercado, Yasuo Kizawa, Keitaro Ueda, Yeping Xiong, Genki Kimura, Audric Moses, Jonathan M Curtis, Kazuhiro Ito, Peter J Barnes
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88168 (2014)
BackgroundAnti-oxidant capacity is crucial defence against environmental or endogenous oxidative stress. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that plays a key defensive role against oxidative an
Externí odkaz:
https://doaj.org/article/ee0a259b16ce4562b54b96c98ae158ca
Autor:
Kazuhiro Ito, Kirstie Anya Lucas, Genki Kimura, Yuki Nishimoto, Yasuo Kizawa, Leah Daly, Pete Strong
Publikováno v:
Journal of Experimental Pathology. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5362e90c3cb4a6bf5abea76c8234f4
https://doi.org/10.33696/pathology.2.011
https://doi.org/10.33696/pathology.2.011
Autor:
Kazuhiro, Ito, Yasuo, Kizawa, Genki, Kimura, Yuki, Nishimoto, Leah, Daly, Ian, Knowles, Mark, Hows, John, Ayrton, Pete, Strong
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 163
PC945 is a novel antifungal agent, optimised for inhaled treatment. In this study, the relationship between antifungal effects of PC945 and its exposure in the lungs was investigated in Aspergillus fumigatus intranasally infected, temporarily neutrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a253171a4c841a18ad8cdcad73747429
https://pubmed.ncbi.nlm.nih.gov/34015430
https://pubmed.ncbi.nlm.nih.gov/34015430
Autor:
Yasuo Kizawa, Keitaro Ueda, Genki Kimura, Yuki Nishimoto, Kotomi Yoshino, Risa Takahashi, Ayaka Nagamoto
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 140(12)
Asthma and chronic obstructive pulmonary disease (COPD) are characterised by chronic inflammation in the lung that is associated with airway obstruction. Inhaled therapy with a combination of corticosteroid and a long-acting β2-agonist is an effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14aa50b9dc0fb67da30a738eecfdab5a
https://pubmed.ncbi.nlm.nih.gov/32921648
https://pubmed.ncbi.nlm.nih.gov/32921648
Publikováno v:
Respiratory infections.
Although Candida spp. are frequently detected in fungal cultures of respiratory secretions, their presence is normally assumed to reflect benign colonization. However, there is growing evidence that Candida spp. is involved in pathogenesis of respira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66543e460dc66fdfda292aba129f4bc4
https://doi.org/10.1183/13993003.congress-2020.2321
https://doi.org/10.1183/13993003.congress-2020.2321
Publikováno v:
Respiratory infections.
Nontypeable Haemophilus influenzae (NTHi) is reported to be colonised more in the lower airways of COPD and asthma patients. The colonization is known to be associated with considerable airway inflammation and cause increased frequency of exacerbatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2dd96ee2fbac78872b9aad3d1e7554
https://doi.org/10.1183/13993003.congress-2020.2322
https://doi.org/10.1183/13993003.congress-2020.2322