Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yasuo IDO"'
Autor:
Akane Kawai, Yuji Nagatomo, Midori Yukino-Iwashita, Ryota Nakazawa, Akira Taruoka, Yusuke Yumita, Asako Takefuji, Risako Yasuda, Takumi Toya, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Takeshi Adachi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 9, p 390 (2023)
A wide range of anti-myocardial autoantibodies have been reported since the 1970s. Among them, autoantibodies against the β1-adrenergic receptor (β1AR-AAb) have been the most thoroughly investigated, especially in dilated cardiomyopathy (DCM). Β1A
Externí odkaz:
https://doaj.org/article/2f8a899f61b64818a5884c42c489c88a
Autor:
Atsushi Sato, Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Toyokazu Kimura, Ayumu Osaki, Takumi Toya, Takayuki Namba, Shogo Endo, Yasuo Ido, Yuji Nagatomo, Yasushi Satoh, Takeshi Adachi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022)
Background Metabolic syndrome is characterized by insulin resistance, which impairs intracellular signaling pathways and endothelial NO bioactivity, leading to cardiovascular complications. Extracellular signal‐regulated kinase (ERK) is a major com
Externí odkaz:
https://doaj.org/article/11c7b16e059d41e78c35f845837509a8
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 6, Pp 1403-1419 (2020)
Abstract One of the biochemical abnormalities found in diabetic tissues is a decrease in the cytosolic oxidized to reduced forms of the nicotinamide adenine dinucleotide ratio (NAD+/NADH also known as pseudohypoxia) caused by oxidation of excessive s
Externí odkaz:
https://doaj.org/article/3188bef211c64148b0d36d6522a5c541
Autor:
Atsushi Sato, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Kazuki Kagami, Yasuo Ido, Takeshi Adachi
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1403 (2022)
Metabolic syndrome (Mets) is an important condition because it may cause stroke and heart disease in the future. Reactive oxygen species (ROSs) influence the pathogenesis of Mets; however, the types of ROSs and their localization remain largely unkno
Externí odkaz:
https://doaj.org/article/53a0067ff1bb40f88843d9e545102d8b
Autor:
Takumi Toya, Kei Ito, Kazuki Kagami, Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Risako Yasuda, Takayuki Namba, Yasuo Ido, Yuji Nagatomo, Katsumi Hayashi, Nobuyuki Masaki, Hirotaka Yada, Takeshi Adachi
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss , Pp - (2020)
Background: Oxidative posttranslational modifications (OPTM) impair the function of Sarcoplasmic/endoplasmic reticulum (SR) calcium (Ca2+) ATPase (SERCA) 2 and trigger cytosolic Ca2+ dysregulation. We investigated the extent of OPTM of SERCA2 in pati
Externí odkaz:
https://doaj.org/article/bbd8f9769d2946e6887f3a4508990afa
Autor:
Nobuyuki Masaki, Yasuo Ido, Toshiyuki Yamada, Youhei Yamashita, Takumi Toya, Bonpei Takase, Naomi M. Hamburg, Takeshi Adachi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 6 (2019)
Background Endothelial insulin resistance is insulin‐insensitivity in the vascular endothelium and can be observed in experimental models. This study aimed to investigate endothelial insulin resistance in patients with suspected coronary artery dis
Externí odkaz:
https://doaj.org/article/db649a3707d1475cb7262c23fde652fc
Autor:
Yasunaga Shiraishi, Norio Ishigami, Takehiko Kujiraoka, Atsushi Sato, Masanori Fujita, Yasuo Ido, Takeshi Adachi
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 471 (2021)
Superoxide dismutase (SOD) is an enzyme that catalyzes the dismutation of two superoxide anions (O2·−) into hydrogen peroxide (H2O2) and oxygen (O2) and is generally known to protect against oxidative stress. Angiotensin II (AngII) causes vascular
Externí odkaz:
https://doaj.org/article/dbed78a9239843bf957a2b0f0ba50b8f
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115341 (2015)
The aging process is perceived as resulting from a combination of intrinsic factors such as changes in intracellular signaling and extrinsic factors, most notably environmental stressors. In skin, the relationship between intrinsic changes and kerati
Externí odkaz:
https://doaj.org/article/5d12ad145c454a4a9f2181ddba1209e4
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97554 (2014)
Liraglutide is a glucagon-like peptide-1 (GLP-1) mimetic used for the treatment of Type 2 diabetes. Similar to the actions of endogenous GLP-1, liraglutide potentiates the post-prandial release of insulin, inhibits glucagon release and increases sati
Externí odkaz:
https://doaj.org/article/cfb633e8fc8e4d2d9bb85f4bbac16ef0
Autor:
Yasuo Ido, Albert Duranton, Fan Lan, Jose M Cacicedo, Tai C Chen, Lionel Breton, Neil B Ruderman
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35092 (2012)
We investigated the effects of AMPK on H(2)O(2)-induced premature senescence in primary human keratinocytes. Incubation with 50 µM H(2)O(2) for 2 h resulted in premature senescence with characteristic increases in senescence-associated ß-galactosid
Externí odkaz:
https://doaj.org/article/bbb3f39fdc9e4de9a24b993ab77d4366