Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Yasuo IDO"'
Autor:
Ayami Naito, Yuji Nagatomo, Akane Kawai, Midori Yukino-Iwashita, Ryota Nakazawa, Akira Taruoka, Asako Takefuji, Risako Yasuda, Takumi Toya, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Takeshi Adachi
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 2, p 141 (2024)
Sodium-glucose cotransporter-2 inhibitors (SGLT-2is) show cardiovascular protective effects, regardless of the patient’s history of diabetes mellitus (DM). SGLT2is suppressed cardiovascular adverse events in patients with type 2 DM, and furthermore
Externí odkaz:
https://doaj.org/article/3f54e617974d45ef981fbbc65ad26c77
Autor:
Akane Kawai, Yuji Nagatomo, Midori Yukino-Iwashita, Ryota Nakazawa, Akira Taruoka, Yusuke Yumita, Asako Takefuji, Risako Yasuda, Takumi Toya, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Takeshi Adachi
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 9, p 390 (2023)
A wide range of anti-myocardial autoantibodies have been reported since the 1970s. Among them, autoantibodies against the β1-adrenergic receptor (β1AR-AAb) have been the most thoroughly investigated, especially in dilated cardiomyopathy (DCM). Β1A
Externí odkaz:
https://doaj.org/article/2f8a899f61b64818a5884c42c489c88a
Autor:
Atsushi Sato, Yusuke Yumita, Kazuki Kagami, Yuki Ishinoda, Toyokazu Kimura, Ayumu Osaki, Takumi Toya, Takayuki Namba, Shogo Endo, Yasuo Ido, Yuji Nagatomo, Yasushi Satoh, Takeshi Adachi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022)
Background Metabolic syndrome is characterized by insulin resistance, which impairs intracellular signaling pathways and endothelial NO bioactivity, leading to cardiovascular complications. Extracellular signal‐regulated kinase (ERK) is a major com
Externí odkaz:
https://doaj.org/article/11c7b16e059d41e78c35f845837509a8
Autor:
Ayumu Osaki, Kazuki Kagami, Yuki Ishinoda, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Kei Ito, Takumi Toya, Yasuo Ido, Takayuki Namba, Nobuyuki Masaki, Yuji Nagatomo, Takeshi Adachi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6486 (2023)
Metabolic syndrome (Mets) is the major contributor to the onset of metabolic complications, such as hypertension, type 2 diabetes mellitus (DM), dyslipidemia, and non-alcoholic fatty liver disease, resulting in cardiovascular diseases. C57BL/6 mice o
Externí odkaz:
https://doaj.org/article/ba872b2be8bf48418aba275d081cef26
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 6, Pp 1403-1419 (2020)
Abstract One of the biochemical abnormalities found in diabetic tissues is a decrease in the cytosolic oxidized to reduced forms of the nicotinamide adenine dinucleotide ratio (NAD+/NADH also known as pseudohypoxia) caused by oxidation of excessive s
Externí odkaz:
https://doaj.org/article/3188bef211c64148b0d36d6522a5c541
Autor:
Midori Yukino-Iwashita, Yuji Nagatomo, Akane Kawai, Akira Taruoka, Yusuke Yumita, Kazuki Kagami, Risako Yasuda, Takumi Toya, Yukinori Ikegami, Nobuyuki Masaki, Yasuo Ido, Takeshi Adachi
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 11, p 1805 (2022)
Heart failure (HF) is a syndrome with global clinical and socioeconomic burden worldwide owing to its poor prognosis. Accumulating evidence has implicated the possible contribution of gut microbiota-derived metabolites, short-chain fatty acids (SCFAs
Externí odkaz:
https://doaj.org/article/13a099fc488e43c7b7e1e17adfe5d455
Autor:
Atsushi Sato, Yasunaga Shiraishi, Toyokazu Kimura, Ayumu Osaki, Kazuki Kagami, Yasuo Ido, Takeshi Adachi
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1403 (2022)
Metabolic syndrome (Mets) is an important condition because it may cause stroke and heart disease in the future. Reactive oxygen species (ROSs) influence the pathogenesis of Mets; however, the types of ROSs and their localization remain largely unkno
Externí odkaz:
https://doaj.org/article/53a0067ff1bb40f88843d9e545102d8b
Autor:
Takehiko Kujiraoka, Kazuki Kagami, Toyokazu Kimura, Yuki Ishinoda, Yasunaga Shiraishi, Yasuo Ido, Shogo Endo, Yasushi Satoh, Takeshi Adachi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8521 (2022)
We previously demonstrated the marked hepatosteatosis and endothelial dysfunction in hepatocyte-specific ERK2 knockout mice (LE2KO) with a high-fat/high-sucrose diet (HFHSD), but detailed metabolic changes and the characteristics in insulin-sensitive
Externí odkaz:
https://doaj.org/article/41f97672c7d7416898facc39cc5f0e7c
Autor:
Takumi Toya, Kei Ito, Kazuki Kagami, Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Risako Yasuda, Takayuki Namba, Yasuo Ido, Yuji Nagatomo, Katsumi Hayashi, Nobuyuki Masaki, Hirotaka Yada, Takeshi Adachi
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss , Pp - (2020)
Background: Oxidative posttranslational modifications (OPTM) impair the function of Sarcoplasmic/endoplasmic reticulum (SR) calcium (Ca2+) ATPase (SERCA) 2 and trigger cytosolic Ca2+ dysregulation. We investigated the extent of OPTM of SERCA2 in pati
Externí odkaz:
https://doaj.org/article/bbd8f9769d2946e6887f3a4508990afa
Autor:
Nobuyuki Masaki, Yasuo Ido, Toshiyuki Yamada, Youhei Yamashita, Takumi Toya, Bonpei Takase, Naomi M. Hamburg, Takeshi Adachi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 6 (2019)
Background Endothelial insulin resistance is insulin‐insensitivity in the vascular endothelium and can be observed in experimental models. This study aimed to investigate endothelial insulin resistance in patients with suspected coronary artery dis
Externí odkaz:
https://doaj.org/article/db649a3707d1475cb7262c23fde652fc