Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasunori Tokunaga"'
Autor:
Yasuhiro Aga, Shigeru Ushiyama, Ayumi Ogawa, Sayaka Ogi, Toru Hasegawa, Yasunori Tokunaga, Hidetoshi Sunamoto, Kazuhiro Onuma, Takashi Matsushita
Publikováno v:
Cancer Research. 78:4835-4835
Background: Cyclin dependent kinase 7 (CDK7) is an attractive target for anticancer drugs due to its dual roles, cell cycle regulation and gene transcription/RNA processing. We synthesized UD-017, a small-molecule, highly selective, orally active CDK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b9bd136c51912a63324b68226be43a3
https://doi.org/10.1158/1538-7445.am2018-4835
https://doi.org/10.1158/1538-7445.am2018-4835
Autor:
Yasuhiro Aga, Shigeru Ushiyama, Yasunori Tokunaga, Takashi Matsushita, Ayumi Ogawa, Hidetoshi Sunamoto, Kazuhiro Onuma, Toru Hasegawa, Sayaka Ogi
Publikováno v:
Cancer Research. 77:LB-297
Background: Cyclin dependent kinase 7 (CDK7) is an attractive target for cancer drugs due to its dual roles, cell cycle regulation & gene transcription/RNA procession. Recent studies show that transcription of some oncogene is highly sensitive to inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59233a816f19c07b2ba2e982dca66cb
https://doi.org/10.1158/1538-7445.am2017-lb-297
https://doi.org/10.1158/1538-7445.am2017-lb-297
Autor:
Hirofumi Matsunaga, Kana Namiki, Yasunori Tokunaga, Kensuke Tanaka, Yoshitoshi Kasuya, Kazuya Murata, Akiyoshi Fukamizu, Akira Sakairi, Jun-Dal Kim, Manabu Shigetomi, Shibakawa Nobuhiko, Tatsuhiko Sudo, Sadao Kimura, Yukinori Wada, Naoki Tokuhara, Junji Ishida, Motohisa Shimizu, Kento Yoshioka, Masahiko Hagihara
Publikováno v:
Journal of Biological Chemistry. 287:24228-24238
One of the mitogen-activated protein kinases, p38, has been found to play a crucial role in various inflammatory responses. In this study, we analyzed the roles of p38α in multiple sclerosis, using an animal model, experimental autoimmune encephalom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c619fb516d426f9148b5342fab7f31e
https://doi.org/10.1074/jbc.m111.338541
https://doi.org/10.1074/jbc.m111.338541
Autor:
Yasunori Tokunaga, Shigeru Ushiyama, Hidetoshi Sunamoto, Ayumi Ogawa, Takashi Matsushita, Yasuhiro Aga, Kazuhiro Onuma, Sayaka Ogi
Publikováno v:
Journal of Clinical Oncology. 35:e14086-e14086
e14086 Background: Cyclin dependent kinase 7 (CDK7) modulates mRNA transcription and some oncogenes are reported to be sensitive to inhibition of transcription in certain cancer cells. CDK7 inhibitors have been considered as an intriguing approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8109fdb2d2dc2e61f9500e3498aacd17
https://doi.org/10.1200/jco.2017.35.15_suppl.e14086
https://doi.org/10.1200/jco.2017.35.15_suppl.e14086
Autor:
Yasunori Tokunaga, Yasuhiro Aga, Kazuhiro Onuma, Shigeyuki Kono, Tohru Hasegawa, Shigeru Ushiyama, Hidetoshi Sunamoto, Takashi Matsushita, Sayaka Ogi, Noriaki Iwase, Ayumi Ogawa
Publikováno v:
Journal of Clinical Oncology. 35:e14085-e14085
e14085 Background: Cyclin dependent kinase 7 (CDK7) is an attractive target for cancer drugs due to its dual roles, cell cycle regulation and gene transcription/RNA procession. We synthesized UD-017, a small molecule, highly selective CDK7 inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b3333e5155722ce3cc7d95d8be0662
https://doi.org/10.1200/jco.2017.35.15_suppl.e14085
https://doi.org/10.1200/jco.2017.35.15_suppl.e14085
Autor:
Hideto Matsuyama, Qingfa Huang, Yasunori Tokunaga, Takashi Watari, Takeshi Maeda, Masaaki Teramoto, Ryo Nakatani
Publikováno v:
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN. 30:328-335
A series of experiments on the facilitated transport of CO2 through supported liquid membranes impregnated with aqueous solutions of various amines as carriers was performed, and the effects of the reaction rate and the chemical equilibrium of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5100d17ca2b84f41bec9e328e5b5d0f
https://doi.org/10.1252/jcej.30.328
https://doi.org/10.1252/jcej.30.328
Autor:
Kana Namiki1, Hirofumi Matsunaga1,2, Kento Yoshioka1, Kensuke Tanaka1, Kazuya Murata3, Junji Ishida3, Akira Sakairi3, Jundal Kim3, Naoki Tokuhara1, Nobuhiko Shibakawa2, Motohisa Shimizu2, Yukinori Wada2, Yasunori Tokunaga2, Manabu Shigetomi2, Masahiko Hagihara2, Sadao Kimura1, Tatsuhiko Sudo4, Akiyoshi Fukamizu3, Yoshitoshi Kasuya1 kasuya@faculty.chiba-u.jp
Publikováno v:
Journal of Biological Chemistry. 7/13/2012, Vol. 287 Issue 29, p24228-24238. 11p.
Publikováno v:
Proceedings of 35th IEEE Conference on Decision & Control; 1996, Issue 1, p177-199-199, 1p