Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yasunori Fukuda"'
Autor:
Ryokichi Koyama, Geza Ambrus-Aikelin, Darbi Witmer, Bi-Ching Sang, Yasunori Fukuda, Hidehisa Iwata, Hideyuki Nakagawa, Masaharu Nakayama, Yusuke Kamada
Publikováno v:
ASSAY and Drug Development Technologies. 16:194-204
The retinoic acid-related orphan receptor gamma T (RORγt) plays an important role in Th17 cell proliferation and functionality. Thus, RORγt inverse agonists are thought to be potent therapeutic agents for Th17-mediated autoimmune diseases, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d9bc10dbf1390655dbeac60d89a052
https://doi.org/10.1089/adt.2018.852
https://doi.org/10.1089/adt.2018.852
Autor:
Yuji Kawamata, Kimio Tohyama, Toshiyuki Ohnishi, Mari Ogasawara-Shimizu, Yasunori Fukuda, Yusuke Nakayama, Misato Kaishima, Ikumi Chisaki
Publikováno v:
Biochemical and Biophysical Research Communications. 484:358-364
Accurate prediction of drug-induced renal toxicity is necessary for development of safer drugs for patients. Cellular assay systems that recapitulate physiologically relevant microenvironments have been proposed for correct estimation of drug respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cb0601ec17a36b3c58bc525678bd6d
https://doi.org/10.1016/j.bbrc.2017.01.124
https://doi.org/10.1016/j.bbrc.2017.01.124
Publikováno v:
FEBS Letters. 590:1576-1585
Lysosomal protein degradation via autophagy strictly regulates cellular protein homoeostasis. Herein we performed high-content screening to identify compounds that inhibit autophagy pathways. We obtained 11 hit compounds and performed cluster analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518b4d7dacd189fd765f08e883711188
https://doi.org/10.1002/1873-3468.12195
https://doi.org/10.1002/1873-3468.12195
Autor:
Kotaro Sakamoto, Satoshi Sogabe, Akito Kadotani, Junichi Sakamoto, Yasunori Fukuda, Yusuke Kamada
Publikováno v:
Biochemical and biophysical research communications. 486(3)
Keap1 constitutively binds to the transcription factor Nrf2 to promote its degradation, resulting in negative modulation of genes involved in cellular protection against oxidative stress. Keap1 is increasingly recognized as an attractive target for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bdc0a2b9d0d9467fd5b6f054a39499
https://pubmed.ncbi.nlm.nih.gov/28315327
https://pubmed.ncbi.nlm.nih.gov/28315327
Publikováno v:
Bioorganicmedicinal chemistry. 25(7)
Protein-protein interaction between dedicator of cytokinesis 2 (DOCK2) and Ras-related C3 botulinum toxin substrate 1 (Rac1) is an attractive intracellular target for transplant rejection and inflammatory diseases. Recently, DOCK2-selective inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69912c237c8cd822d6911289bcfbbf9
https://pubmed.ncbi.nlm.nih.gov/28284862
https://pubmed.ncbi.nlm.nih.gov/28284862
Publikováno v:
大阪産業大学論集. 自然科学編. 124:11-19
A study on thermoluminescence (TL) and thermally stimulated exoelectron emission (TSEE) has been performed for CaF_2 single crystal irradiated by a femtosecond (fs) near-infrared laser. Focused laser pulses with approximately 250 fs duration and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::abd595bc382005a973713eb5de3e79a2
http://id.nii.ac.jp/1338/00001416/
http://id.nii.ac.jp/1338/00001416/
Publikováno v:
大阪産業大学論集. 自然科学編. 124:21-30
The thermoluminescence (TL) of Ca_5(PO_4)_3Cl doped with Pr ions has been studied for use as a thermoluminescence dosimeter (TLD) material. The TL glow spectra of Ca_5(PO_4)_3Cl:Pr irradiated with UV ray show a liner relation between TL glow intensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::2be6ae84016781e0f332bc64cc894917
http://id.nii.ac.jp/1338/00001417/
http://id.nii.ac.jp/1338/00001417/
Publikováno v:
大阪産業大学論集. 自然科学編. 124:1-10
A study on thermoluminescence (TL) and thermally stimulated exoelectron emission (TSEE) has been performed for LiF single crystal irradiated by focused Ga^+ ion beam (FIB). The result indicates that the intensities of TL and TSEE glow spectra depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::5942b919a4ada99e3e35d814172452e7
http://id.nii.ac.jp/1338/00001415/
http://id.nii.ac.jp/1338/00001415/
Autor:
Ülo Langel, Yoshimasa Kawaguchi, Yasunori Fukuda, Nobutaka Fujii, Yasumaru Hatanaka, Ikuhiko Nakase, Shinya Oishi, Katsuya Okawa, Tomoka Takatani-Nakase, Masao Matsuoka, Shiroh Futaki, Gen Tanaka, Ryo Masuda, Astrid Gräslund, Kazuya Shimura
Publikováno v:
Chemistry & Biology. 19:1437-1446
SummaryCXCR4 is a coreceptor of HIV-1 infection in host cells. Through a photocrosslinking study to identify receptors involved in internalization of oligoarginine cell-penetrating peptides (CPPs), we found that CXCR4 serves as a receptor that stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1d7cf005fa09e4ae2f29bfce67869e
https://doi.org/10.1016/j.chembiol.2012.09.011
https://doi.org/10.1016/j.chembiol.2012.09.011
Autor:
Nao, TANAKA, Yasunori, FUKUDA
Publikováno v:
大阪産業大学論集. 自然科学編. 123:91-102
Thermoluminescence phosphors available for the estimation of ultraviole (UV) irradiation dose are examined. A several kind of lanthanide elements are doped in pure CaF_2 powder crystals and properties of the TL to UV radiation are observed. It is fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::3d3325d0625daba3c701a09a3c380f3a
http://id.nii.ac.jp/1338/00001407/
http://id.nii.ac.jp/1338/00001407/