Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Yasunori, Iwao"'
Autor:
Akira Minami, Yuka Fujita, Jun Goto, Ayano Iuchi, Kosei Fujita, Yasuyo Mikami, Mako Shiratori, Ami Ishii, Samir Mitragotri, Yasunori Iwao, Hiroaki Kanazawa, Yuuki Kurebayashi, Tadanobu Takahashi, Tadamune Otsubo, Kiyoshi Ikeda, Takashi Suzuki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Reduction of elastin in the skin causes various skin diseases as well as wrinkles and sagging with aging. Sialidase is a hydrolase that cleaves a sialic acid residue from sialoglycoconjugate. Cleavage of sialic acid from microfibrils by the
Externí odkaz:
https://doaj.org/article/b206dd55f73d4226b1ced499d9b7d30c
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 108 (2023)
The use of exosomes encapsulating therapeutic agents for the treatment of diseases is of increasing interest. However, some concerns such as limited efficiency and scalability of conventional drug encapsulation methods to exosomes have still remained
Externí odkaz:
https://doaj.org/article/54bcc1e3b2c748578f13fc1ab9ea59f2
Autor:
Tadashi Hattori, Hiroki Tagawa, Makoto Inai, Toshiyuki Kan, Shin-ichiro Kimura, Shigeru Itai, Samir Mitragotri, Yasunori Iwao
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Nobiletin (NOB), a flavonoid, has extremely low water solubility and low oral bioavailability; however, despite these problems, various physiological effects have been investigated in vitro. In the present study, we investigated the transder
Externí odkaz:
https://doaj.org/article/63fa0dea7c1444fd9daa6d6a0abd59dc
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
The aim of this study was to design and evaluate muco-adhesive orally disintegrating tablets manufactured by microwave irradiation and containing polysaccharide. We prepared orally disintegrating tea tablets (ODTTs) containing a 1 w/w% mass fraction
Externí odkaz:
https://doaj.org/article/1dfa34ffa950415ba810cf4f06ce6306
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad40a25ebeaf3bdc2246e58a51319236
https://doi.org/10.1021/acs.molpharmaceut.3c00103
https://doi.org/10.1021/acs.molpharmaceut.3c00103
Publikováno v:
ACS Biomaterials Science & Engineering. 7:595-604
Recently, choline and geranic acid (CAGE), an ionic liquid (IL), has been recognized to be a superior biocompatible material for oral and transdermal drug delivery systems (DDS). When CAGE is administered, CAGE would be exposed to various types of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bbca9fddcb04f487201c434acabc31
https://doi.org/10.1021/acsbiomaterials.0c01324
https://doi.org/10.1021/acsbiomaterials.0c01324
Autor:
Daiki Hirai, Hiroki Tsunematsu, Shin-ichiro Kimura, Shigeru Itai, Toshiro Fukami, Yasunori Iwao
Publikováno v:
International journal of pharmaceutics. 625
Amorphous solid dispersion (ASD) is a preparation widely used for improving the solubility and low oral absorbability of poorly water-soluble drugs, but the quantitative analysis of its dissolution profiles and its supersaturation status remains an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf0c2a12c97786db784160439ce6539
https://pubmed.ncbi.nlm.nih.gov/35970282
https://pubmed.ncbi.nlm.nih.gov/35970282
Autor:
Yasunori Iwao
Publikováno v:
Journal of the Society of Powder Technology, Japan. 57:103-107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f23b462c7435b0d8ebbfba5acf184ba
https://doi.org/10.4164/sptj.57.103
https://doi.org/10.4164/sptj.57.103
Autor:
Kouya Kimoto, Kento Ohashi, Yasunori Iwao, Masatoshi Karashima, Katsuhiko Yamamoto, Toshiro Fukami, Yukihiro Ikeda
Publikováno v:
International journal of pharmaceutics. 621
The states of amorphous drug and/or newly generated crystalline drug on the surface of amorphous drug samples must be carefully characterized to validate the quality of pharmaceutical amorphous drugs. In this study, we investigated whether individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5a74e202c327c503d6fd792b37106e
https://pubmed.ncbi.nlm.nih.gov/35504428
https://pubmed.ncbi.nlm.nih.gov/35504428