Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Yasunobu Aoki"'
Autor:
Yasunobu Aoki, Mizuki Ohno, Michiyo Matsumoto, Michi Matsumoto, Kenichi Masumura, Takehiko Nohmi, Teruhisa Tsuzuki
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-11 (2021)
Abstract Background Base pair mismatches in genomic DNA can result in mutagenesis, and consequently in tumorigenesis. To investigate how mismatch repair deficiency increases mutagenicity under oxidative stress, we examined the type and frequency of m
Externí odkaz:
https://doaj.org/article/d0f190b721784fe9a066c6b40e96ba1b
Autor:
Elina Drakvik, Rolf Altenburger, Yasunobu Aoki, Thomas Backhaus, Tina Bahadori, Robert Barouki, Werner Brack, Mark T.D. Cronin, Barbara Demeneix, Susanne Hougaard Bennekou, Jacob van Klaveren, Carsten Kneuer, Marike Kolossa-Gehring, Erik Lebret, Leo Posthuma, Lena Reiber, Cynthia Rider, Joëlle Rüegg, Giuseppe Testa, Bart van der Burg, Hilko van der Voet, A. Michael Warhurst, Bob van de Water, Kunihiko Yamazaki, Mattias Öberg, Åke Bergman
Publikováno v:
Environment International, Vol 134, Iss , Pp - (2020)
The number of anthropogenic chemicals, manufactured, by-products, metabolites and abiotically formed transformation products, counts to hundreds of thousands, at present. Thus, humans and wildlife are exposed to complex mixtures, never one chemical a
Externí odkaz:
https://doaj.org/article/c43c2dfa7ba44c1fbb764a91e6a1d76e
Autor:
Yasunobu Aoki, Daisuke Nakajima, Michiyo Matsumoto, Mayuko Yagishita, Michi Matsumoto, Rie Yanagisawa, Sumio Goto, Kenichi Masumura, Takehiko Nohmi
Publikováno v:
Genes and Environment, Vol 40, Iss 1, Pp 1-12 (2018)
Abstract Background Previously we found that DNA adducts were accumulated in the lungs of the rats exposed to ambient air in the Tokyo metropolitan area. To examine chronological change in in vivo mutagenicity of airborne particles, extracts produced
Externí odkaz:
https://doaj.org/article/5af3ebc9256a4a47b0052eacfd662a06
Autor:
Yasunobu Aoki
Publikováno v:
Genes and Environment, Vol 39, Iss 1, Pp 1-12 (2017)
Abstract Various kind of chemical substances, including man-made chemical products and unintended products, are emitted to ambient air. Some of these substances have been shown to be mutagenic and therefore to act as a carcinogen in humans. National
Externí odkaz:
https://doaj.org/article/85f73d309d73490eb21dc800a4d23eff
Autor:
Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki
Supplementary Table 1 from Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d49e5f6475c87ec76d3bb5d36e16ec9
https://doi.org/10.1158/0008-5472.22366544
https://doi.org/10.1158/0008-5472.22366544
Autor:
Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki
The lung is an organ that is sensitive to mutations induced by chemicals in ambient air, and transgenic mice harboring guanine phosphoribosyltransferase (gpt) gene as a target gene are a well-established model system for assessing genotoxicity in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a001179e23d305f7ad2aa254823b96f2
https://doi.org/10.1158/0008-5472.c.6495182.v1
https://doi.org/10.1158/0008-5472.c.6495182.v1
Autor:
Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki
Supplementary Table 4 from Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955649fcc5a784d64448f75c00c61779
https://doi.org/10.1158/0008-5472.22366535.v1
https://doi.org/10.1158/0008-5472.22366535.v1
Autor:
Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki
Supplementary Table 2 from Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b76a437ba445afe0b288ce97d78a930
https://doi.org/10.1158/0008-5472.22366541
https://doi.org/10.1158/0008-5472.22366541
Autor:
Masayuki Yamamoto, Takehiko Nohmi, Ken Itoh, Ken-ichi Masumura, Hirohisa Takano, Kyoko Hiyoshi, Michi Matsumoto, Kimiko Amanuma, Akiko H. Hashimoto, Yasunobu Aoki
Supplementary Table 3 from Enhanced Spontaneous and Benzo(a)pyrene-Induced Mutations in the Lung of Nrf2-Deficient gpt Delta Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0208d287fef35d834dfb941d58e3c994
https://doi.org/10.1158/0008-5472.22366538.v1
https://doi.org/10.1158/0008-5472.22366538.v1
Autor:
Teruhisa Tsuzuki, Kenichi Masumura, Michi Matsumoto, Yasunobu Aoki, Michiyo Matsumoto, Mizuki Ohno, Takehiko Nohmi
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-11 (2021)
Genes and Environment
Genes and Environment
Background Base pair mismatches in genomic DNA can result in mutagenesis, and consequently in tumorigenesis. To investigate how mismatch repair deficiency increases mutagenicity under oxidative stress, we examined the type and frequency of mutations