Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yasunari Munemasa"'
Autor:
Takashi Kanamoto, Nazariy Souchelnytskyi, Takuji Kurimoto, Yasuhiro Ikeda, Hiroaki Sakaue, Yasunari Munemasa, Yoshiaki Kiuchi
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Background. To investigate how transcorneal electric stimulation (TES) affects the retina, by identifying those proteins up- and downregulated by transcorneal electric stimulation (TES) in the retina of rats. Methods. Adult Wistar rats received TES o
Externí odkaz:
https://doaj.org/article/6117dcd239d846b1b7d6e90cc8d672b8
Autor:
Naoto Tokuda, Yasushi Kitaoka, Akiko Matsuzawa, Junsuke Miyamoto, Shinsuke Sakae, Yasunari Munemasa, Hitoshi Takagi
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Purpose. To examine the efficacy of ophthalmic rebamipide suspensions on ocular surface disorders induced by antiglaucoma eye drops. Patients and Methods. Forty eyes of 40 patients receiving latanoprost (0.005%) and timolol (0.5%) were included in th
Externí odkaz:
https://doaj.org/article/60ccbb60f8594feeabe2e1317a2aa776
Autor:
Kazuyuki Isenoumi, Toshio Kumai, Yasushi Kitaoka, Masamitsu Motoki, Yuka Kitaoka, Kohei Kuribayashi, Yasunari Munemasa, Jiro Kogo, Shinichi Kobayashi, Satoki Ueno
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 1, Pp 108-114 (2004)
The aim of this study was to investigate whether an excitotoxic concentration of N-methyl-D-aspartate (NMDA) increases the expression of the phosphorylated cAMP response element-binding protein (p-CREB) and the DNA-binding activity of the cAMP respon
Externí odkaz:
https://doaj.org/article/22c31b7e35f149bfbbec2bcbc1beeb2c
Autor:
Yasunari Munemasa, Chang-Sheng Chang, Jacky M K Kwong, Haksu Kyung, Yasushi Kitaoka, Joseph Caprioli, Natik Piri
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34810 (2012)
Nell2 is a neuron-specific protein containing six epidermal growth factor-like domains. We have identified Nell2 as a retinal ganglion cell (RGC)-expressed gene by comparing mRNA profiles of control and RGC-deficient rat retinas. The aim of this stud
Externí odkaz:
https://doaj.org/article/4127f2be3cd646f79caea89ca340eb7d
Autor:
Yasunari Munemasa
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Acute primary angle closure (APAC) is a disease of ophthalmic urgency; lack of treatment can lead to blindness. Even after adequate treatment for APAC, subsequent elevated acute intraocular pressure induces severe neuronal damage which can result in
Autor:
Hiroki Sasaki, Yasushi Kitaoka, K Mitsui, Hitoshi Takagi, Akira Shiono, Yasunari Munemasa, Jiro Kogo, H. Takeda
Publikováno v:
Eye
Purpose The purpose of this study was to compare 27-gauge (27G) with 25-gauge (25G) microincision vitrectomy in patients with epiretinal membrane (ERM). Participants Seventy-four eyes of 66 patients undergoing 3-port pars plana vitrectomy using 27G o
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology
Purpose The p62, also called sequestosome 1 (SQSTM1), plays a crucial role in tumor necrosis factor (TNF)-induced optic nerve degeneration. Brimonidine has been shown to have protective effects on retinal ganglion cell bodies, although its role in th
Autor:
Junji Yodoi, Akihiro Ohira, Yasushi Kitaoka, Sachiko Kaidzu, Yasunari Munemasa, Kaori Kojima, Masaki Tanito, Kana Sase, Hitoshi Takagi
Publikováno v:
Experimental eye research. 152
Interleukin (IL)-1β, a proinflammatory cytokine, is a key mediator in several acute and chronic neurological diseases. Thioredoxin-1 (TRX1) acts as an antioxidant and plays a protective role in certain neurons. We examined whether exogenous TRX1 exe
Publikováno v:
Journal of Neurochemistry. 115:1508-1519
Mitochondrial abnormality has been implicated in various models of retinal ganglion cell (RGC) degeneration. We investigated modulation of mitochondrial membrane permeability and apoptosis-inducing factor (AIF) translocation in a rat experimental gla
Publikováno v:
Brain Research. 1362:133-140
We examined the histologic findings of optic nerve axons and changes in kinesin-1, which is involved in axonal flow, in N-methyl-d-aspartate (NMDA)-induced neurotoxicity in rats. Substantial degenerative changes visualized as black profiles and pale