Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yasunari Kayashima"'
Autor:
Kiko Kanno, Yasunari Kayashima, Kazuji Tamura, Takako Miyara, Kento Baba, Megumi Koganei, Midori Natsume, Shinjiro Imai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Life span is increasing in developed countries as Japan, and an aging society is becoming a problem. In fact, healthy lifespan is not extended, and it is desired to extend it by functional food. Cacao (Theobroma cacao) contains various activ
Externí odkaz:
https://doaj.org/article/40cb8a2e1ecd4ebba06a1f403ffa80de
Autor:
Yuya Ohhara, Takumi Kawashima, Kimiko Yamakawa-Kobayashi, Yoshitatsu Ohishi, Yasunari Kayashima
Publikováno v:
Biomedical Research. 41:131-138
Increasing oxidative stress seems to be the result of an imbalance between free radical production and antioxidant defenses. During the course of aging, oxidative stress causes tissue/cellular damage, which is implicated in numerous age-related disea
Autor:
Miho Ohama, Yasunari Kayashima, Hiroyuki Tezuka, Shinjiro Imai, Maiko Suzuki, Yuki Katayanagi
Publikováno v:
SSRN Electronic Journal.
Summary: The deacetylation of PGC-1α by the activation of sirtuins (SIRTs) with resveratrol (Res) promotes mitochondrial function and metabolic homeostasis. However, Res may not have the ability to specifically promote the deacetylation of PGC-1α b
Autor:
Kimiko, Yamakawa-Kobayashi, Yuya, Ohhara, Takumi, Kawashima, Yoshitatsu, Ohishi, Yasunari, Kayashima
Publikováno v:
Biomedical research (Tokyo, Japan). 41(3)
Increasing oxidative stress seems to be the result of an imbalance between free radical production and antioxidant defenses. During the course of aging, oxidative stress causes tissue/cellular damage, which is implicated in numerous age-related disea
Autor:
Takeshi Ishii, Misaki Sato, Shigenori Kumazawa, Junko Chimoto, Kimiko Yamakawa-Kobayashi, Tsutomu Nakayama, Shinichi Murata, Toshimichi Asanuma, Kanako Matsuura, Kazuo Mochizuki, Yasunari Kayashima
Publikováno v:
Biochemistry and Biophysics Reports. 4:417-424
Background Polyphenols in tea are considered beneficial to human health. However, many such claims of their bioactivity still require in vitro and in vivo evidence. Results Using Drosophila melanogaster as a model multicellular organism, we assess th
Autor:
Yuya Ohhara, Yasunari Kayashima, Kimiko Yamakawa-Kobayashi, Eri Otagi, Toshinao Goda, Nobuhiko Kasezawa
Publikováno v:
Journal of nutrigenetics and nutrigenomics. 10(5-6)
Background/Aims: It is possible that carnosinase (CNDP1) and cellular nonspecific dipeptidase (CNDP2) have important roles in protecting cells and tissues against the damage of oxidative stress. Oxidative stress and subsequent inflammation are key fa
Autor:
Yuki Katayanagi, Ryuta Fukutomi, Yasunari Kayashima, Shigeru Hiramoto, Keiko Tanaka, Shinjiro Imai
Publikováno v:
Scientific Reports
Sirtuins are enzymes that catalyze NAD+ dependent protein deacetylation. The natural polyphenolic compound resveratrol received renewed interest when recent findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects
Publikováno v:
Biochemical and Biophysical Research Communications. 434:258-262
Here we report an additional Drosophila transheterozygote InR(GS15311)/InR(GS50346) carrying two different P-element-inducible alleles of insulin-like receptor gene (InR). InR(GS15311)/InR(GS50346) flies exhibit the following phenotypes previously re
Autor:
Keiko Yamanashi, Shigenori Kumazawa, Ayaka Sato, Kimiko Yamakawa-Kobayashi, Yasunari Kayashima
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 76:2107-2111
Royal jelly (RJ), a honeybee-derived product, has been found to possess developmental and physiological bioactivity in the fruit fly, Drosophila melanogaster, but little is known about the in vivo bioactivity of freeze-dried RJ (FDRJ) powder, which i
Autor:
Kimiko Yamakawa-Kobayashi, Yoshiki Hayashi, Yuya Ohhara, Satoru Kobayashi, Yasunari Kayashima
Publikováno v:
Zoological Science. 29:83-89
An invertebrate biogenic amine, octopamine, plays diverse roles in multiple physiological processes (e.g. neurotransmitter, neuromodulator, and circulating neurohormone). Octopamine is thought to function by binding to G-protein-coupled receptors. In