Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yasunari, Nakai"'
Autor:
Eugenio G. Araujo, Jun Feng, Munir Boodhwani, Pierre Voisine, Keith Michael, Cesario Bianchi, Yasunari Nakai, Frank W. Sellke, Jian Li, Shigetoshi Mieno
Publikováno v:
The Annals of Thoracic Surgery. 81:634-641
Background Recent studies have shown that angiogenesis is regulated by a balance between activators and inhibitors. We investigated the effects of hypercholesterolemia on the functional angiogenic response and collateral formation induced by chronic
Autor:
Yukiya Nomura, Hitoshi Horimoto, Yasunari Nakai, Shigetoshi Mieno, Kenichi Nakahara, Shinjiro Sasaki
Publikováno v:
European Surgical Research. 35:108-114
Objectives: Left ventricular (LV) mechanical unloading is known to reduce the hemodynamic demands of failing LV, resulting in improved myocyte contractility. This study was designed to examine effects of LV unloading on β-adrenergic receptor (BAR) e
Autor:
Hitoshi Horimoto, Shigetoshi Mieno, Kenichi Nakahara, Shinjiro Sasaki, Yasunari Nakai, Yukiya Nomura
Publikováno v:
Journal of Surgical Research. 105:181-188
Background. To investigate whether the sulfonylurea glimepiride affects the myoprotective effects of ischemic preconditioning (IPC), isolated rabbit hearts were perfused with Krebs-Henseleit solution. Methods. Eight hearts underwent IPC consisting of
Autor:
Shinjiro Sasaki, Yasunari Nakai, Yukiya Nomura, Ken ich Nakahara, Shigetoshi Mieno, Hitoshi Horimoto
Publikováno v:
The Journal of Heart and Lung Transplantation. 21:440-445
The development of atherosclerotic cardiovascular complications caused by hyperlipidemia is a common and serious problem for long-term survivors of organ transplantation. However, adhesion molecules such as intercellular adhesion molecule (ICAM)-1 an
Publikováno v:
European Surgical Research. 34:244-250
Background: Inhibition of Na+/H+ exchange has been shown to provide functional protection during ischemia and reperfusion in mature heart. This study was undertaken to elucidate the effect of Na+/H+ exchange inhibitor HOE642 in the aged rabbit heart.
Autor:
Yasunari Nakai, Akira Fujiwara, Hiroshi Morita, Hitoshi Fukumoto, Takahiro Tokuhara, Takashi Nishimoto, Nanritsu Matsuyama
Publikováno v:
Nihon Kyukyu Igakukai Zasshi. 6:167-171
We report the successful repair of a ruptured abdominal aortic aneurysm in a 66-year-old man. He was admitted with cardiopulmonary arrest. Emergency surgery was successfully performed after cardiopulmonary resuscitation. Although postoperative MRSA i
Autor:
Jian Li, Frank W. Sellke, Munir Boodhwani, Roger J. Laham, Yasunari Nakai, Cesario Bianchi, Pierre Voisine, Jun Feng, Shigetoshi Mieno, Basel Ramlawi
Publikováno v:
Circulation. 114
Background— Although 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) can restore endothelial function in coronary disease, in vitro and murine studies have shown their effects on myocardial angiogenesis to be biphasic
Autor:
Tamer Malik, Cesario Bianchi, Pierre Voisine, Tanveer A. Khan, Yasunari Nakai, Jun Feng, Audrey Rosinberg, Frank W. Sellke, Marc Ruel, Jian Li, Shu-Hua Xu
Publikováno v:
Circulation. 112
Background— Nitric oxide availability, which is decreased in advanced coronary artery disease associated with endothelial dysfunction, is an important mediator of fibroblast growth factor-2 (FGF-2)–induced angiogenesis. This could explain the dis
Autor:
Hitoshi Horimoto, Shigetoshi Mieno, Shinjiro Sasaki, Fusao Watanabe, Yasunari Nakai, Eisuke Furuya
Publikováno v:
The Annals of thoracic surgery. 74(4)
Background . The purpose of this study was to determine whether ischemic preconditioning (IPC) provides myoprotective effects in post-myocardial infarction (MI) hearts, and whether beta adrenergic signaling is involved in IPC. Methods . Rats were sub
Autor:
Hitoshi Horimoto, Katsuhide Maeda, Yoshihiro Suematsu, Toshiya Ohtsuka, Yasunari Nakai, Shigetoshi Mieno, Shinichi Takamoto
Publikováno v:
The Annals of thoracic surgery. 73(1)
Background . This study examines whether the chronic administration of nipradilol, a nitric oxide–releasing β-adrenergic blocker, decreases ischemia-reperfusion injury. Methods . Rats were treated with nipradilol (10 mg/kg per day orally) or a veh