Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yasumoto, Mizoguchi"'
Autor:
Ikuo Matsuura, Keiichi Itoh, Hiroyuki Izumi, Harutaka Oku, Ryota Tanaka, Nao Nakano, Nobuhito Hoshino, Masato Naya, Tohru Uesugi, Kei Shiozawa, Katsumi Endoh, Hitoshi Hojo, Sakiko Fujii, Ken-ichi Noritake, Atsuko Hishikawa, Seiki Matsuo, Kaoru Yabe, Kazuhiro Chihara, Kiyoshi Matsumoto, Akihiro Arima, Yoji Miwa, Makoto Ema, Ayumi Inoue, Hanako Nishizawa, Hiroshi Mineshima, Ikuro Takakura, Hiroshi Inada, Yasumoto Mizoguchi, Maki Maeda, Yoshinori Hosokawa, Yuzo Asano, Hiroaki Aoyama, Masao Horimoto, Hidenori Miyata, Tatsuya Shimizu, Ryohei Yokoi, Kazuhiro Shimomura, Hiroko Noyori, Hiroaki Hara, Hashihiro Higuchi, Toshiaki Yamauchi, Takafumi Ohta
Publikováno v:
Congenital Anomalies. 52:155-161
Historical control data on rabbit prenatal developmental toxicity studies, performed between 1994-2010, were obtained from 20 laboratories, including 11 pharmaceutical and chemical companies and nine contract laboratories, in Japan. In this paper, da
Autor:
Takako Endoh, Ryo Haneda, Yasumoto Mizoguchi, Hiroyasu Mizuguchi, Yuzo Asano, Kazuya Fukuda, Tetsuya Matsuoka
Publikováno v:
The Journal of Toxicological Sciences. 35:773-778
Changes in blood parameters, especially those related to blood coagulations, were examined on gestational days (GDs) 6, 18 and 28 in Japanese White rabbits. As compared with the non-pregnant group, the following changes were observed in the pregnant
Autor:
Ryo Kamata, Hiroyasu Mizuguchi, Tetsuya Matsuoka, Kazuya Fukuda, Yasumoto Mizoguchi, Tsutomu Ishikawa, Takako Endoh, Yuzo Asano
Publikováno v:
Laboratory Animals. 44:33-39
Changes in clinical pathology parameters, particularly those related to blood coagulation, were examined throughout the gestation period in New Zealand White rabbits. As compared with the non-pregnant group, the following major changes were observed
Autor:
M. Hirose, Kumiko Ogawa, Satoru Takahashi, Tomoyuki Shirai, Mitsuru Futakuchi, Yasumoto Mizoguchi
Publikováno v:
Journal of Toxicologic Pathology. 21:77-87
We have already shown that forestomach lesions induced by 24 weeks administration of genotoxic carcinogens, 8-nitroquinoline (8-NQ), 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (AF-2), N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or N-methylnitrosoureth
Autor:
Ema Sano, Kotaro Serizawa, Ryo Kamata, Tetsuya Matsuoka, Yasumoto Mizoguchi, Yuzo Asano, Toshikazu Ishikura
Publikováno v:
Congenital Anomalies. 47:108-111
Prenatal development of Kbl:Dutch rabbits was studied in comparison with Kbl:New Zealand white rabbits. Significantly accelerated ossification of the 5th and 6th sternebrae and a low incidence of fetuses with a 13th rib were characteristic features i
Publikováno v:
The Journal of Toxicological Sciences. 32:565-570
The purpose of the present investigation is to evaluate the restraining effects of protecting jackets attached from the pre-mating period and thereafter up to completion of the fetal organogenesis in rabbits. Forty (40) Kbl:NZW mated rabbits 6 to 10
Autor:
Keisuke Akagi, Masao Hirose, Mitsuru Futakuchi, Tomoyuki Shirai, Yasumoto Mizoguchi, Tsuyoshi Yamaguchi
Publikováno v:
Cancer Letters. 188:163-170
Differences in the modifying effects of green tea catechins (GTC) on intestinal carcinogenesis by different formulations, doses and administration routes were investigated in male rats pretreated with 1,2-dimethylhydrazine (DMH). One hundred and eigh
Autor:
Atsushi Nakamura, Yasumoto Mizoguchi, Tomoyuki Shirai, Masao Hirose, Keisuke Akagi, Toru Hoshiya
Publikováno v:
Cancer Letters. 168:23-29
Modifying effects of green tea catechins (GTCs) on the post-initiation stage of colon, lung and thyroid carcinogenesis were examined in F344 male rats. Groups of 20 animals were given subcutaneous injections of 40 mg/kg body wt of 1,2-dimethylhydrazi
Autor:
Tokutaro Miki, Kumiko Ogawa, Yasumoto Mizoguchi, Pleumjit Boonyaphiphat, Tomoyuki Shirai, Mitsuru Futakuchi, Masao Hirose
Publikováno v:
International Journal of Cancer. 76:851-856
The effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), phenylethylisothiocyanate (PEITC), 3-O-ethylascorbic acid, 3-O-dodecylcarbomethylascorbic acid and n-heptadecane-8, 10-dione were analyzed in a rat multiorgan carcinogenesis model. Groups o
Autor:
Masae Tatematsu, Tomoyuki Shirai, Ken Ichi Inada, Hideaki Yada, Toshio Imai, Mitsuru Futakuchi, Hayao Nakanishi, Tsuneo Masui, Yasumoto Mizoguchi
Publikováno v:
Cancer Letters. 112:33-45
The carcinogenic and metastatic processes are thought to consist of a sequence of steps, and animal models featuring highly metastatic lesions are clearly necessary to allow analysis of the whole process of transformation from preneoplastic changes t