Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yasumi Yoshizane"'
Autor:
Chihiro Yamasaki, Yuji Ishida, Ami Yanagi, Yasumi Yoshizane, Yuha Kojima, Yuko Ogawa, Yutaka Kageyama, Yumiko Iwasaki, Seiichi Ishida, Kazuaki Chayama, Chise Tateno
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0237809 (2020)
Chimeric mice with humanized livers are considered a useful animal model for predicting human (h-) drug metabolism and toxicity. In this study, the characteristics of fresh h-hepatocytes (cFHHs, PXB-cells®) isolated from chimeric mice (PXB-mice®) w
Externí odkaz:
https://doaj.org/article/6e8ca299c9f44766b957319744985e9c
Autor:
Chise Tateno, Chihiro Yamasaki, Yumiko Iwasaki, Yasumi Yoshizane, Ami Yanagi, Yuji Ishida, Yutaka Kageyama, Seiichi Ishida, Kazuaki Chayama, Yuko Ogawa, Yuha Kojima
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0237809 (2020)
PLoS ONE, Vol 15, Iss 9, p e0237809 (2020)
Chimeric mice with humanized livers are considered a useful animal model for predicting human (h-) drug metabolism and toxicity. In this study, the characteristics of fresh h-hepatocytes (cFHHs, PXB-cells®) isolated from chimeric mice (PXB-mice®) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fa7d4269e28c68d6d4c3e5c64ba95a
https://pubmed.ncbi.nlm.nih.gov/32915792
https://pubmed.ncbi.nlm.nih.gov/32915792
Autor:
Ami Yanagi, Shigeru Ohta, Go Sugahara, Yaichiro Kotake, Seigo Sanoh, Yuji Ishida, Keishi Kisoh, Chise Tateno, Chieri Fujino, Yasumi Yoshizane, Yuka Tamura
Publikováno v:
Biologicalpharmaceutical bulletin. 42(8)
Drug-induced liver injury (DILI) is a common side effect of several medications and is considered a major factor responsible for the discontinuation of drugs during their development. Cholestasis is a DILI that results from impairment of bile acid tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d70759e2dd33c137539df35fb00b7c
https://pubmed.ncbi.nlm.nih.gov/31366871
https://pubmed.ncbi.nlm.nih.gov/31366871
Autor:
Yasumi Yoshizane, Chise Tateno, Yuji Ishida, Yuka Tamura, Seigo Sanoh, Shigeru Ohta, Yaichiro Kotake, Yuto Yamachika
Publikováno v:
The Journal of Toxicological Sciences. 42:589-596
It is important to consider susceptibility to drug-induced toxicity between animals and humans. Chimeric mice with a humanized liver are expected to predict hepatotoxicity in humans. Drug-induced phospholipidosis (DIPL), in which phospholipids accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261ff823e4719641e9fa9633e949bcb1
https://doi.org/10.2131/jts.42.589
https://doi.org/10.2131/jts.42.589
Autor:
Keishi Kisoh, Yasumi Yoshizane, Michinori Kohara, Yuji Ishida, Go Sugahara, Chise Tateno, Suzue Furukawa
Publikováno v:
Journal of Hepatology. 70:e548-e549
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3dd876d91e8ccac331bae33d6abd5e
https://doi.org/10.1016/s0618-8278(19)31088-6
https://doi.org/10.1016/s0618-8278(19)31088-6
Autor:
Koichi Watashi, Takaji Wakita, Chihiro Yamasaki, Chise Tateno, C. Nelson Hayes, Kazuaki Chayama, Kazuyuki Fujikawa, Hiromi Abe, Yasumi Yoshizane, Ami Yanagi, Yuji Ishida
Publikováno v:
The American Journal of Pathology. 185:1275-1285
The molecular mechanisms underlying the hepatitis B virus (HBV) life cycle are poorly understood because of the lack of appropriate in vitro infection models. Herein, we report a highly effective in vitro HBV infection system using fresh human hepato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c5f12c00870d8fd252b1d0f1b32981
https://doi.org/10.1016/j.ajpath.2015.01.028
https://doi.org/10.1016/j.ajpath.2015.01.028
Chimeric Mice with Humanized Livers: A Unique Tool for in Vivo and in Vitro Enzyme Induction Studies
Autor:
Yasumi Yoshizane, Masakazu Kakuni, Asato Tachibana, Chihiro Yamasaki, Chise Tateno, Yuji Ishida
Publikováno v:
International Journal of Molecular Sciences; Volume 15; Issue 1; Pages: 58-74
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 58-74 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 58-74 (2013)
We performed in vivo and in vitro studies to determine the induction of human cytochrome P450 (CYP) using chimeric mice with humanized liver (PXB-mice®) and human hepatocytes isolated from the PXB-mice (PXB-cells), which were derived from the same d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf27258d9691d69fbf3daa8d356f360
https://doi.org/10.3390/ijms15010058
https://doi.org/10.3390/ijms15010058
Autor:
Yasumi Yoshizane, Katsutoshi Yoshizato, Tsuyoshi Yokoi, Kinji Asahina, Hiroshi Hino, Yoshinori Soeno, Toshimasa Asahara, Chise Tateno, Miho Kataoka, Chihiro Yamasaki, Asato Tachibana, Naomi Saito, Toshinori Furukawa, Rie Utoh
Publikováno v:
The American journal of pathology. 165(3)
Human hepatocytes were transplanted into urokinase-type plasminogen activator-transgenic SCID mice (uPA/SCID mice), which are immunodeficient and undergo liver failure. The transplanted cells were characterized in terms of their in vivo growth potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2eb596367a2eb2f0596e8812af650f
https://pubmed.ncbi.nlm.nih.gov/15331414
https://pubmed.ncbi.nlm.nih.gov/15331414
Autor:
Masakazu Kakuni, Chihiro Yamasaki, Asato Tachibana, Yasumi Yoshizane, Yuji Ishida, Chise Tateno
Publikováno v:
International Journal of Molecular Sciences; Jan2014, Vol. 15 Issue 1, p58-74, 17p
Autor:
Seigo Sanoh1 sanoh@hiroshima-u.ac.jp, Yuto Yamachika1, Yuka Tamura1, Yaichiro Kotake1, Yasumi Yoshizane2, Yuji Ishida2,3, Chise Tateno2,3, Shigeru Ohta1
Publikováno v:
Journal of Toxicological Sciences. Oct2017, Vol. 42 Issue 5, p589-596. 8p.