Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yasumi, Nakayama"'
Autor:
Amanda Linkous, Demosthenes Balamatsias, Matija Snuderl, Lincoln Edwards, Ken Miyaguchi, Teresa Milner, Batsheva Reich, Leona Cohen-Gould, Andrew Storaska, Yasumi Nakayama, Emily Schenkein, Richa Singhania, Stefano Cirigliano, Tarig Magdeldin, Ying Lin, Gouri Nanjangud, Kalyani Chadalavada, David Pisapia, Conor Liston, Howard A. Fine
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://doaj.org/article/f28ebd0f3f8540688e121a8ec45550af
Autor:
Stefano M. Cirigliano, Andrew J. Storaska, Ken Miyaguchi, Kalyani Chadalavada, Howard A. Fine, Amanda G. Linkous, Ying Lin, Gouri Nanjangud, Batsheva Reich, Leona Cohen-Gould, Teresa A. Milner, Richa Singhania, Yasumi Nakayama, Emily Schenkein, Tarig Magdeldin, Conor Liston, Matija Snuderl, Demosthenes Balamatsias, David J. Pisapia, Lincoln A. Edwards
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936188fe78fcd6c0dbaba6a700bb9cb6
http://www.sciencedirect.com/science/article/pii/S2211124719302426
http://www.sciencedirect.com/science/article/pii/S2211124719302426
Autor:
Gregory G, Gick, Kaveri, Arora, Jeffrey M, Sequeira, Yasumi, Nakayama, Shao-Chiang, Lai, Edward V, Quadros
Publikováno v:
Experimental cell research. 396(1)
Cellular uptake of vitamin B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a123410e21b872f0908db3874276e3a
https://pubmed.ncbi.nlm.nih.gov/32898552
https://pubmed.ncbi.nlm.nih.gov/32898552
Autor:
Kaveri Arora, Yasumi Nakayama, Edward V. Quadros, Gregory G. Gick, Jeffrey M. Sequeira, Shao-Chiang Lai
Publikováno v:
Experimental Cell Research. 396:112256
Cellular uptake of vitamin B12 (cobalamin, Cbl) is mediated by a cell surface receptor (TCblR/CD320) that binds transcobalamin (TC) saturated with Cbl. TC is secreted by the vascular endothelium, has a relatively short half-life, binds Cbl with high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b44ca7f13d5009b7ccfeb7e0f18b3c
https://doi.org/10.1016/j.yexcr.2020.112256
https://doi.org/10.1016/j.yexcr.2020.112256
Publikováno v:
The FASEB Journal. 27:2988-2994
The membrane receptor TCblR/CD320 binds transcobalamin (TC) saturated with vitamin B12 [cobalamin (Cbl)] and mediates cellular uptake of the vitamin. The specificity of TC for Cbl and of the receptor for TC-Cbl ensures efficient uptake of Cbl into ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4670e5ac94769e4a1aac82bd2b781492
https://doi.org/10.1096/fj.13-230185
https://doi.org/10.1096/fj.13-230185
Publikováno v:
Journal of cancer therapy
Cobalamin uptake into cells is mediated by the CD320 receptor for transcobalamin-bound cobalamin. Optimum receptor expression is associated with proliferating cells and therefore, in many cancers this receptor expression is up regulated. Delivering d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1146261767825e7a3b09327345fb7c76
https://doi.org/10.4236/jct.2013.46122
https://doi.org/10.4236/jct.2013.46122
Publikováno v:
Experimental Cell Research. 317:1603-1607
The clinical phenotype of cobalamin (Cbl) deficiency is dictated by the essential role of this vitamin in two key enzymatic reactions. Multiple proteins and receptors participate in the absorption, transport and delivery of this vitamin to tissue cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09e9174df04d48d4a50d0a1ccd7e189
https://doi.org/10.1016/j.yexcr.2011.02.016
https://doi.org/10.1016/j.yexcr.2011.02.016
Publikováno v:
Gene. 466:49-55
Cellular uptake of cobalamin (Cbl) is mediated by the transcobalamin receptor (TCblR) that binds and internalizes transcobalamin (TC) saturated with Cbl. These receptors are expressed in actively proliferating cells and are down-regulated in quiescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d84493f9a8d513e3f3584260e126f85
https://doi.org/10.1016/j.gene.2010.07.004
https://doi.org/10.1016/j.gene.2010.07.004
Publikováno v:
Blood. 113:186-192
The transcobalamin (TC, TCII) receptor (TCblR) on the plasma membrane binds TC- cobalamin (Cbl) and internalizes the complex by endocytosis. This receptor was purified from human placental membranes by affinity chromatography. Tryptic digest of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d123d71d3439ac23c5fc1b61cc9885b
https://doi.org/10.1182/blood-2008-05-158949
https://doi.org/10.1182/blood-2008-05-158949
Publikováno v:
Biochemical and Biophysical Research Communications. 327:1006-1010
Cellular uptake of vitamin B12 (cobalamin, Cbl) is mediated by a receptor expressed on the plasma membrane that binds transcobalamin (TC) saturated with Cbl and internalizes the TC–Cbl by endocytosis. A few reports have described the characterizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4d5dd22793cb08c872b7588be6dbd0
https://doi.org/10.1016/j.bbrc.2004.12.103
https://doi.org/10.1016/j.bbrc.2004.12.103