Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yasuko Tsukazaki"'
Genetic variants of UDP-glucuronosyltransferases 1A1, 1A6, and 1A9 in cynomolgus and rhesus macaques
Autor:
Takahiro Mikami, Yasuko Tsukazaki, Hideshi Tsusaki, Shinichi Ikushiro, Norie Murayama, Yasuharu Nakanishi, Yasuhiro Uno, Hiroshi Yamazaki
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(1)
1. In the cynomolgus macaque, UDP-glucuronosyltransferases (UGTs) 1As have similar molecular and enzymatic characteristics to those of their human orthologs. However, genetic polymorphisms in major cynomolgus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877df3098929c35001cd81e38db92712
https://pubmed.ncbi.nlm.nih.gov/32811258
https://pubmed.ncbi.nlm.nih.gov/32811258
Autor:
Minori Osamura, Mitsuo Oshimura, Mari Hashimoto, Masato Takiguchi, Kanako Kazuki, Rika Hirashima, Naoto Senda, Nico Scheer, Daisuke Satoh, Takehito Kaneko, Yasuko Tsukazaki, Jiro Kuze, Naoyo Kajitani, Shoko Takehara, Yasuhiro Kazuki, Tsuneo Deguchi, Takashi Yamamoto, Tetsushi Sakuma, Riko Wakatsuki, Ryoichi Fujiwara, Satoshi Abe, Tomoji Mashimo, Kaoru Kobayashi, Masumi Hirabayashi, Atsushi Kurihara
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Genomically humanized animals overcoming species differences are invaluable for biomedical research. Although rats would be preferred over mice for several applications, generation of a humanized model is restricted to mice due to the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6abe0e80c40a0d93fc48413bfcd08
https://pubmed.ncbi.nlm.nih.gov/30718425
https://pubmed.ncbi.nlm.nih.gov/30718425
Autor:
Satoshi Abe, Tetsushi Sakuma, Kaoru Kobayashi, Takashi Yamamoto, Shoko Takehara, Naoto Senda, Kazuomi Nakamura, Kazuhisa Honma, Kan Chiba, Yasuhiro Kazuki, Azusa Okada, Yasuko Tsukazaki, Kanako Kazuki, Asami Oji, Mitsuo Oshimura, Masahito Ikawa
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abe, S., Kobayashi, K., Oji, A. et al. Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology. Sci Rep 7, 15189 (2017). https://doi.org/10.1038/s41598-017-15033-0
Cytochrome P450, family 3, s
Cytochrome P450, family 3, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eafa2d0bbfc51c114b71e7459b2e25
https://pubmed.ncbi.nlm.nih.gov/29123154
https://pubmed.ncbi.nlm.nih.gov/29123154
Autor:
Shigeru Yamada, Naoto Senda, Mitsuo Oshimura, Kinya Kubo, Hiroyuki Kugoh, Yasuhiro Kazuki, Yasuko Tsukazaki
Publikováno v:
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 32(2)
Human plasma arginine vasopressin (AVP) levels serve as a clinically relevant marker of diabetes and related syndromes. We developed a highly sensitive method for measuring human plasma AVP using high-performance liquid chromatography tandem mass spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c8093e67a80ba3ba1bc21200892134
https://pubmed.ncbi.nlm.nih.gov/26860558
https://pubmed.ncbi.nlm.nih.gov/26860558
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 57:291-300
Our GLP (Good Laboratory Practice)-free laboratory continues to develop state-of-the-art technologies that will provide a cutting-edge service to our clients.•We will respond to client requests promptly.•We will have a good relationship with clie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e706665d9ce6239abaacad2fed580aa4
https://doi.org/10.5702/massspec.57.291
https://doi.org/10.5702/massspec.57.291
Autor:
Shoko Takehara, Takeshi Oshima, Mitsuo Oshimura, Tetsuya Terasaki, Kan Chiba, Satoshi Abe, Naoyo Kajitani, Kinya Kubo, Yoshimi Kuroiwa, Yasuko Tsukazaki, Yasuhiro Kazuki, Masato Takiguchi, Hiroki Kawakami, Sumio Ohtsuki, Kazuma Tomizuka, Hidetoshi Hoshiya, Naoto Senda, Sasitorn Aueviriyavit, Kaoru Kobayashi
Publikováno v:
Human molecular genetics. 22(3)
Human CYP3A is the most abundant P450 isozyme present in the human liver and small intestine, and metabolizes around 50% of medical drugs on the market. The human CYP3A subfamily comprises four members (CYP3A4, CYP3A5, CYP3A7, CYP3A43) encoded on hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8439494970380633299f1fc95f2bbd21
https://pubmed.ncbi.nlm.nih.gov/23125282
https://pubmed.ncbi.nlm.nih.gov/23125282