Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yasuko Terao"'
Publikováno v:
Stroke Research and Treatment, Vol 2011 (2011)
Stroke is a dynamic event in the brain involving heterogeneous cells. There is now compelling clinical evidence that prolonged, moderate cerebral hypothermia initiated within a few hours after severe ischemia can reduce subsequent neuronal death and
Externí odkaz:
https://doaj.org/article/babcf63b1703456e849eb584271c1b88
Autor:
Takahiko Yano, Yusuke Adachi, Yuji Shimizu, Masaharu Nakayama, Taiji Asami, Katsuya Sakimura, Yasuko Terao
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
Oxytocin (OT) is a neuropeptide involved in a wide variety of physiological actions, both peripherally and centrally. Many human studies have revealed the potential of OT to treat autism spectrum disorders and schizophrenia. OT interacts with the OT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c5cecdcae546073b098d7e86007695
https://pubmed.ncbi.nlm.nih.gov/28438540
https://pubmed.ncbi.nlm.nih.gov/28438540
Autor:
Hideyuki Nakagawa, Masato Yoshikawa, Eiji Kimura, Yuji Ishichi, Honda Eiji, Jun Terauchi, Yuuichi Arakawa, Hiroyuki Ohta, Atsuko Suzuki, Naoyuki Kanzaki, Takayuki Kawai, Yasuko Terao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:3898-3902
A novel series of triple reuptake inhibitors were explored by ligand-based drug design. A cyclic structure was designed from cyclopropane derivative 5 using the core structure of reported monoamine reuptake inhibitors, leading to the formation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af9ee8cd56c93a8f5d67ae3d81d5953
https://doi.org/10.1016/j.bmcl.2014.06.046
https://doi.org/10.1016/j.bmcl.2014.06.046
Publikováno v:
Stroke Research and Treatment
Stroke Research and Treatment, Vol 2011 (2011)
Stroke Research and Treatment, Vol 2011 (2011)
Stroke is a dynamic event in the brain involving heterogeneous cells. There is now compelling clinical evidence that prolonged, moderate cerebral hypothermia initiated within a few hours after severe ischemia can reduce subsequent neuronal death and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acc9b6876220fb2a62c82c3e37d47ca
https://doi.org/10.4061/2011/809874
https://doi.org/10.4061/2011/809874
Publikováno v:
Neuroscience Research. 57:424-433
Hypothermia is the only neuroprotective therapy proven to be clinically effective. Identifying the molecules that play important roles in the efficacy of hypothermia, we developed a multi-channel computer-controlled system, in which the brain tempera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481e0eca3bc1bea58d63f51bd976847a
https://doi.org/10.1016/j.neures.2006.12.002
https://doi.org/10.1016/j.neures.2006.12.002
Autor:
Mari Asada, Shoji Fukusumi, Chieko Kitada, Yuji Kawamata, Yoshio Matsumoto, Takanori Yamamoto, Masaki Tanaka, Yasuko Terao, Tsutomu Kurokawa, Takahiko Yano, Takuya Watanabe, Kuniko Kikuchi, Masahiko Fujino, Osamu Nishimura, Yasushi Shintani, Haruo Onda, Yasuhiko Ibata, Shuji Hinuma, Ryo Fujii, Norio Iijima, Masaki Hosoya, Yugo Habata
Publikováno v:
Nature Cell Biology. 2:703-708
Only a few RFamide peptides have been identified in mammals, although they have been abundantly found in invertebrates. Here we report the identification of a human gene that encodes at least three RFamide-related peptides, hRFRP-1-3. Cells transfect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d0dcfdd0b1f5f4080380a5b50a3fb8
https://doi.org/10.1038/35036326
https://doi.org/10.1038/35036326
Autor:
Jun Terauchi, Yuuichi Arakawa, Honda Eiji, Yasuko Terao, Hideyuki Nakagawa, Masato Yoshikawa, Takayuki Kawai, Hiroyuki Ohta, Takashi Nakahata, Yuji Ishichi, Atsuko Suzuki, Naoyuki Kanzaki, Eiji Kimura
Publikováno v:
Bioorganicmedicinal chemistry. 21(15)
A novel triple reuptake inhibitor with low potential of liabilities associated with cationic amphiphilic drug (CAD) was identified following an analysis of existing drugs. Low molecular weight (MW < ca. 300), low aromatic ring count (number = 1) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9bec354bc09378195995aa723bc09d
https://pubmed.ncbi.nlm.nih.gov/23769168
https://pubmed.ncbi.nlm.nih.gov/23769168
Autor:
Yasuko Terao, Yasushi Shintani
Publikováno v:
Advances in the Treatment of Ischemic Stroke
Cerebral ischemia is a serious dynamic event in the brain involving heterogeneous cell types. Neuroprotective agents represent a potential approach for the treatment of acute stroke. Presently, recombinant tissue plasminogen activator (rtPA) is the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e8c845398b716f06df9edcf9197123
https://doi.org/10.5772/32228
https://doi.org/10.5772/32228
Autor:
Masato Shimojo, Satoru Asahi, Hiroyuki Ohta, Kazuko Hirai, Yasuko Terao, Yasufumi Sakura, Yoshihiro Kiyota, Hidenori Kamiguchi, Yasushi Shintani, Saku Miyamoto
Publikováno v:
Neuroreport. 20(8)
Although moderate hypothermia is one of the most robust and effective techniques available for reducing ischemic injury, its key mechanism still remains unclear. Our proteomic analysis of the brains of rats treated with a 2-h middle cerebral artery o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9869abec877d360b88d3ac2b8a91ff4e
https://pubmed.ncbi.nlm.nih.gov/19352207
https://pubmed.ncbi.nlm.nih.gov/19352207
Publikováno v:
Neuroscience research. 64(1)
Although hypothermia is one of the most robust neuroprotectants clinically available, its underlying mechanisms remain unclear. Through microarray gene expression analysis, we previously identified several key molecules potentially involved in the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8569ef350a5ecb7c0a70a3107daf1f42
https://pubmed.ncbi.nlm.nih.gov/19428685
https://pubmed.ncbi.nlm.nih.gov/19428685