Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yasuko Soejima"'
Autor:
Kazuyuki Yanai, Masao Shibata, Ko-ichi Kawahara, Shinichi Watanabe, Takayuki Ohshima, Yasuko Soejima, Ryouji Fujii, Masanori Nakata, Ikuro Maruyama, Takayuki Oishi, Toshihiro Nakajima, Satoko Aratani, Akiyoshi Fukamizu, Masatoshi Hagiwara, Katsumi Inoue, Tetsuya Amano
Publikováno v:
Biochemical and Biophysical Research Communications. 266:417-424
Recent studies have implicated acetylation of several nuclear proteins such as histones and p53 on their epsilon-portion of lysine residues in eukaryotic transcription. Here we raised a specific polyclonal antibody against epsilon-acetylated lysine.
Autor:
Yasufumi Kaneda, Yasuko Soejima, Ko-Ichi Kawahara, Isao Kitajima, Naohiro Hanyu, Ikuro Maruyama, Toshikazu Kubo, Ryo Yamada
Publikováno v:
Arthritis & Rheumatism. 40:2118-2127
Objective. To develop gene therapy for patients with human T cell leukemia virus type I (HTLV-I)-associated arthropathy (HAAP), we investigated the effects of ribozyme-mediated cleavage of HTLV-I tax/rex messenger RNA (mRNA) on synovial overgrowth. M
Autor:
Naohiro Hanyu, Ryuki Hirano, Ryo Yamada, Yasuko Soejima, Satoko Arahira, Yasufumi Kaneda, Isao Kitajima, Shoji Yamaoka, Ikuro Maruyama
Publikováno v:
Journal of Biological Chemistry. 272:27099-27106
We investigated the usefulness of ribozymes in inhibiting the expression of human T-cell leukemia virus type I (HTLV-I) gene. Two hammerhead ribozymes that were against HTLV-I rex (RR) and tax (TR) mRNA were synthesized. Both ribozymes were sequence-
Autor:
Toshihiro Nakajima, Ko-ichi Kawahara, Takami Matsuyama, Yasuko Soejima, Ikuro Maruyama, Isao Kitajima
Publikováno v:
Biochemical and Biophysical Research Communications. 204:244-251
To investigate how the number of mast cells is controlled, we studied a murine mastocytoma cell line. Based on electron microscopic observation of nuclear condensation and electrophoretic evidence with DNA fragmentation, these mastocytoma wells were
Publikováno v:
Biochemical and Biophysical Research Communications. 203:1181-1187
We have recently demonstrated that NF-kappa B is involved in a thrombin-signaling and that the antisense oligodeoxynucleotides (ODNs) of NF-kappa B has a marked inhibitory effect on thrombin-induced cellular responses. In this study, we demonstrate t
Autor:
Mitsuhiro Osame, Itsuro Higuchi, Fusako Usuki, Ikuro Maruyama, Yasuko Soejima, Masakazu Hattori
Publikováno v:
Muscle & Nerve. 14:245-252
A clonal human skeletal muscle cell line showing acid maltase deficiency (AMD) was established through the transfection of origin-defective SV40 DNA. The low acid alpha-glucosidase activity and glycogenosomes in this clone corresponded to AMD. This c
Autor:
William A. Dittman, Mitsuhiro Osame, Takahiko Ito, Hidehiko Saito, Yasuko Soejima, Ikuro Maruyama, Kohei Ogawa, Shuji Yamamoto
Publikováno v:
Thrombosis Research. 61:301-310
We previously reported that the expression of thrombomodulin on the MEG-01, a cell line from human megakaryoblastic leukemia, was increased by agents that increase intracellular cAMP. In this paper we examine the effect of these agents on cultured hu
Publikováno v:
Bone. 19(3)
Osteoblasts are affected by TNF-alpha overproduction by immune cells during inflammation. We demonstrate that apoptosis is induced in murine osteoblastic MC3T3-E1 cells by exceeding the concentrations 100 units/mL of TNF-alpha and 10 mumol/L of synth
Autor:
Jun-ichiro Tsutsui, Isao Kitajima, Yasuko Soejima, T. Shimayama, N. Hanyu, Hiroshi Shin, Masayuki Ozawa, Ikuro Maruyama, Takeshi Tokioka, Ko-ichi Kawahara
Publikováno v:
Journal of cell science. 109
Human T-cell leukemia virus type I (HTLV-I) Tax protein induces the expression of host cellular genes, some of which are crucial in cell proliferation and differentiation. We examined the mechanisms by which HTLV-I Tax protein induces phenotypic chan
Autor:
Yasuko Soejima, K. Kawano, Ikuro Maruyama, Kyoko Nakano, Toshihiro Nakajima, Kazuhiro Abeyama, S. Oh
Publikováno v:
Biochemical and biophysical research communications. 212(3)
The expression of P-selectin was more upregulated following the exposure to nonionic low osmolar contrast agents than to ionic contrast agents. Exposure to nonionic contrast agents led to marked adhesion of leukocytes to endothelial cells. Thrombomod