Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yasuko Imamura"'
Autor:
Hideki Iwamoto, Hiroyuki Suzuki, Atsutaka Masuda, Takahiko Sakaue, Toru Nakamura, Toshimitsu Tanaka, Miwa Sakai, Yasuko Imamura, Hirohisa Yano, Takuji Torimura, Hironori Koga, Kaori Yasuda, Masakatsu Tsurusaki, Takahiro Seki, Takumi Kawaguchi
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108797- (2024)
Summary: Current approved anti-angiogenic drugs (AAD) for hepatocellular carcinoma (HCC) inhibit tumor angiogenesis, but affect the hepatic vasculature resulting in adverse effects. Tumor endothelial cells (TECs) differ from normal endothelial cells.
Externí odkaz:
https://doaj.org/article/031aaec1a390453d82be69fc0ff3cd30
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Takahiro Seki, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Yasuko Imamura, Takashi Niizeki, Masahito Nakano, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Miwa Sakai, Kazutoyo Morita, Masamichi Nakayama, Tomoharu Yoshizumi, Ryoko Kuromatsu, Hirohisa Yano, Yihai Cao, Hironori Koga, Takuji Torimura
Publikováno v:
Cancer Communications, Vol 43, Iss 4, Pp 415-434 (2023)
Abstract Background Antiangiogenic tyrosine kinase inhibitors (TKIs) provide one of the few therapeutic options for effective treatment of hepatocellular carcinoma (HCC). However, patients with HCC often develop resistance toward antiangiogenic TKIs,
Externí odkaz:
https://doaj.org/article/b014bbfe6ace4455a5688b7b5212c659
Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis
Autor:
Toru Nakamura, Hironori Koga, Hideki Iwamoto, Victor Tsutsumi, Yasuko Imamura, Masako Naitou, Atsutaka Masuda, Yu Ikezono, Mitsuhiko Abe, Fumitaka Wada, Takahiko Sakaue, Takato Ueno, Masaaki Ii, Cantas Alev, Atsuhiko Kawamoto, Takayuki Asahara, Takuji Torimura
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Ex vivo expansion of autologous cells is indispensable for cell transplantation therapy of patients with liver cirrhosis. The aim of this study was to investigate the efficacy of human ex vivo-expanded CD34+ cells for treatment of cirrhotic rat liver
Externí odkaz:
https://doaj.org/article/ba8dfbdb893c47a8b0a8c5883ae2f795
Autor:
Hideki Iwamoto, Hiroyuki Suzuki, Atsutaka Masuda, Takahiko Sakaue, Toru Nakamura, Toshimitsu Tanaka, Miwa Sakai, Yasuko Imamura, Hirohisa Yano, Takuji Torimura, Hironori Koga, Masakatsu Tsurusaki, Takumi Kawaguchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7425e55095023e2f1640db9e50325927
https://doi.org/10.2139/ssrn.4423991
https://doi.org/10.2139/ssrn.4423991
Autor:
Hironori Koga, Yasuko Imamura, Toshimitsu Tanaka, Hideki Iwamoto, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Hiroyuki Suzuki, Hirohisa Yano, Takumi Kawaguchi
Publikováno v:
Cancer Research. 83:5870-5870
Background: We previously identified 14 isoforms of T-cell factor (TCF)-4, a key transcriptional factor in the Wnt signaling pathway, from human hepatocellular carcinoma (HCC) cell lines (Exp Cell Res 2011). The TCF-4J and K pair has been characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beaefb0a66ba3c90dd46d342bdf9a14d
https://doi.org/10.1158/1538-7445.am2023-5870
https://doi.org/10.1158/1538-7445.am2023-5870
Autor:
Atsutaka Masuda, Hideki Iwamoto, Hironori Koga, Yasuko Imamura, Hiroyuki Suzuki, Tomoyuki Ushijima, Toshimitsu Tanaka, Toru Nakamura, Takahiko Sakaue, Takuji Torimura, Yoshinobu Okabe
Publikováno v:
Cancer Research. 80:3137-3137
Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal neoplasm because of difficulties in early detection. Therefore, identification of biomarkers for early diagnosis of PDAC is crucial. Several studies have reported that exosomes in blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50dd5e8e4efc37732481979de71f4c9d
https://doi.org/10.1158/1538-7445.am2020-3137
https://doi.org/10.1158/1538-7445.am2020-3137
Autor:
Hirohisa Yano, Takuji Torimura, Yasuko Imamura, Hiroyuki Suzuki, Toru Nakamura, Toshimitsu Tanaka, Takahiko Sakaue, Hironori Koga, Dan Nakano, Atsutaka Masuda, Hideki Iwamoto
Publikováno v:
Cancer Research. 80:2627-2627
Background: We previously identified a unique Wnt target gene CLAUDIN-2, whose expression level was regulated by isoforms of the Wnt signal transcription factor T-cell factor-4 (Exp Cell Res 2011, Liver Int 2013). CLAUDIN-2 (CLDN-2) was highly expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9143b2d39c841ca299f92b5352123480
https://doi.org/10.1158/1538-7445.am2020-2627
https://doi.org/10.1158/1538-7445.am2020-2627
Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis
Autor:
Takato Ueno, Yasuko Imamura, Atsutaka Masuda, Takahiko Sakaue, Takuji Torimura, Toru Nakamura, Atsuhiko Kawamoto, Takayuki Asahara, Hironori Koga, Yu Ikezono, Masako Naitou, Cantas Alev, Víctor Tsutsumi, Fumitaka Wada, Mitsuhiko Abe, Hideki Iwamoto, Masaaki
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Ex vivo expansion of autologous cells is indispensable for cell transplantation therapy of patients with liver cirrhosis. The aim of this study was to investigate the efficacy of human ex vivo-expanded CD34(+) cells for treatment of cirrhotic rat liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84422b5d071e1219b09e5e269a84a934
http://www.sciencedirect.com/science/article/pii/S232905011630167X
http://www.sciencedirect.com/science/article/pii/S232905011630167X
Autor:
Hironori Koga, Atsutaka Masuda, Masaru Fukahori, Toru Nakamura, Yoshinobu Okabe, Tatsuyuki Kakuma, Yasuko Imamura, Fumitaka Wada, Toshimitsu Tanaka, Takuji Torimura, Takahiko Sakaue, Mitsuhiko Abe, Hideki Iwamoto, Tomoyuki Ushijima
Publikováno v:
Cancer Research. 78:2660-2660
Background: It is known that cancer cells surviving in ascites show cancer stem cell (CSC)-like features. The CSC-like cells abundantly secrete extracellular vesicles called exosomes, which may play important roles in maintaining tumor-specific micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::252ff222bb2f9f34b636e9afd62c220c
https://doi.org/10.1158/1538-7445.am2018-2660
https://doi.org/10.1158/1538-7445.am2018-2660
Autor:
Takuji Torimura, Fumitaka Wada, Tomoyuki Ushijima, Masaru Fukahori, Hideki Iwamoto, Yoshinobu Okabe, Yasuko Imamura, Toru Nakamura, Keisuke Miwa, Tatsuyuki Kakuma, Osamu Tsuruta, Hironori Koga, Takahiko Sakaue, Atsutaka Masuda, Yu Ikezono
Publikováno v:
Pancreatology. 16:S143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc25f523f1dfb4b1f6e5dffac042893
https://doi.org/10.1016/j.pan.2016.06.515
https://doi.org/10.1016/j.pan.2016.06.515