Long-term administration of whey alters atrophy, gene expression profiles and dysfunction of salivary glands in elderly rats

Autor: Tomasz D. Pieczonka, Aneta M. Bragiel, Hideaki Horikawa, Kana Fukuta, Masami Yoshioka, Yasuko Ishikawa

Publikováno v: Journal of Functional Foods, Vol 21, Iss , Pp 349-358 (2016)

Salivary glands in elderly individuals commonly exhibit morphological changes and dysfunction resulting in xerostomia. Long-term (4-week) drinking of whey prevented and/or restored age-dependent decline of salivary volume and protein concentration, a

Externí odkaz: https://doaj.org/article/64829b6d27c0456aa0656f7d7d49f9a3

Effect of Jersey cow defatted dry milk on salivary volume and composition in elderly persons : a pilot study

Autor: Yasuko Ishikawa, Yuko Takeuchi, Tomasz D. Pieczonka, Masami Yoshioka, Aneta M Bragiel-Pieczonka, Shizuko Yanagisawa

Publikováno v: The journal of medical investigation : JMI. 68(3.4)

The administration of Leu57-Leu58-His59-Lys60 (LLHK), Leu58-His59-Lys60 (LHK), and His59-Lys60 (HK) from β-lactoglobulin C variant, which is specific to Jersey cow milk, has been shown to prevent and/or restore the age-dependent atrophy and function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f4e66e38bd95c64e7f1a2058502426
https://pubmed.ncbi.nlm.nih.gov/34759145

Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: The Translocation of Aquaporin-5 From Lipid Rafts to the Apical Plasma Membranes of Parotid Glands of Normal Rats and the Impairment of It in Diabetic or Aged Rats

Autor: Yasuko Ishikawa, Noriko Inoue, Yuan Zhenfang, Yoshiko Nakae

Publikováno v: Journal of Pharmacological Sciences, Vol 96, Iss 3, Pp 271-275 (2004)

Salivary secretion from rat salivary glands occurs in response to stimulation by acetylcholine and norepinephrine released from nerve endings. Aquaporin-5 (AQP5) localizes in lipid rafts under control conditions and is induced to traffic to the apica

Externí odkaz: https://doaj.org/article/e059e9311e6c4df3b0506683c76da2cb

Systemic network for dietary inorganic phosphate adaptation among three organs

Autor: Hiroko Segawa, Yasuko Ishikawa, Toru Fujii, Sawako Tatsumi, Yuji Shiozaki, Ai Hanazaki, Kayo Ikuta, Ken-ichi Miyamoto, Ichiro Kaneko

Publikováno v: Pflügers Archiv - European Journal of Physiology. 471:123-136

Inorganic phosphate (Pi) secretion from the salivary glands and dietary Pi are key Pi sources. The regulatory mechanisms of Pi homeostasis in the salivary glands are unknown. We investigated how salivary Pi concentrations are regulated by dietary Pi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2116f3b39e53e52e3d909a7fde55912
https://doi.org/10.1007/s00424-018-2242-9

Activation of muscarinic receptors in rat parotid acinar cells induces AQP5 trafficking to nuclei and apical plasma membrane

Autor: Gota Cho, Mariusz T. Skowronski, Di Wang, Masayuki Shono, Yasuko Ishikawa, Tomasz D. Pieczonka, Søren Nielsen, Aneta M. Bragiel

Publikováno v: Cho, G, Bragiel, A M, Wang, D, Pieczonka, T D, Skowronski, M T, Shono, M, Nielsen, S & Ishikawa, Y 2015, ' Activation of muscarinic receptors in rat parotid acinar cells induces AQP5 trafficking to nuclei and apical plasma membrane ', BBA Gene Regulatory Mechanisms, vol. 1850, no. 4, pp. 784-793 . https://doi.org/10.1016/j.bbagen.2015.01.009

BACKGROUND: The subcellular distribution of aquaporin-5 (AQP5) in rat parotid acinar cells in response to muscarinic acetylcholine receptor (mAChR) activation remains unclear.METHODS: Immunoconfocal and immunoelectron microscopy were used to visualiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1d5c0e6daef151b80464d001c56698
https://doi.org/10.1016/j.bbagen.2015.01.009