Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Yasuko, Obata"'
Autor:
Hiroki Saitoh, Ken Takami, Hiroki Ohnari, Yoshihiko Chiba, Yuri Ikeuchi-Takahashi, Yasuko Obata
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:289-298
Autor:
Qihui Xu, Yifan Wu, Hiroki Saito, Yuki Ofuchi, Haruna Setoyama, Takayuki Furuishi, Kaori Fukuzawa, Etsuo Yonemochi, Yasuko Obata
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:111-119
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:31-40
Intercellular lipids fill the interstices of corneocytes and serve a barrier function. The amount of transdermal water evaporation varies depending on the packing structure of intercellular lipids, as this structure is important for maintaining barri
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:652-660
The hydrocarbon-chain packing structure of intercellular lipids in the stratum corneum (SC) is critical to the skin's barrier function. We previously found that formation of V-shaped ceramide reduces the barrier function of skin. There are few agents
Publikováno v:
Powder Technology. 383:115-130
Scored tablets are produced to facilitate easy and uniform division of tablets. One of the most critical quality attributes of the scored tablet is its dividing uniformity. To clarify the tablet dividing mechanism, we proposed a novel algorithm on th
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:72-80
Intercellular lipids in the stratum corneum protect the living body from invasion by allergens and pathogens, and also suppresses water evaporation within the body. It is important to understand how differences in the microstructure of intercellular
Publikováno v:
Chemicalpharmaceutical bulletin. 69(7)
The hydrocarbon-chain packing structure of intercellular lipids in the stratum corneum (SC) is critical to the skin's barrier function. We previously found that formation of V-shaped ceramide reduces the barrier function of skin. There are few agents
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:1144-1151
Definitive screening design (DSD) is a new class of small three-level experimental design that is attracting much attention as a technical tool of a quality by design (QbD) approach. The purpose of this study is to examine the usefulness of DSD for Q
Publikováno v:
Journal of Drug Delivery Science and Technology. 52:1021-1031
Effects of residual stresses on the mechanical characteristics of tablets such as tensile strength (TS) and disintegration time (DT) were investigated. The residual stresses were simulated using the finite element method (FEM), in which the powder co