Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Yasuki AKIE"'
Autor:
Hiroyuki Saito, Ryuichi Kambayashi, Ai Goto, Mihoko Hagiwara-Nagasawa, Kiyotaka Hoshiai, Yoshio Nunoi, Hiroko Izumi-Nakaseko, Yasuki Akie, Yoshinori Takei, Akio Matsumoto, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 3, Pp 268-272 (2021)
We assessed concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables using a cross-over design in intact beagle dogs (n = 4). Elevation of inhaled halothane from 1.0% to 2.0% or isofl
Externí odkaz:
https://doaj.org/article/ef116513f3774b34b0e2f2b49449f29f
Autor:
Hiroyuki Saito, Ryuichi Kambayashi, Mihoko Hagiwara-Nagasawa, Yoshio Nunoi, Ai Goto, Hiroko Izumi-Nakaseko, Shinichi Kawai, Yoshinori Takei, Akio Matsumoto, Kiyotaka Hoshiai, Yasuki Akie, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 16-22 (2021)
We compared dl-sotalol-induced electrocardiographic responses in intact dogs using a repeated-measures design among 1% halothane anesthesia, 1.5% isoflurane anesthesia with nitrous oxide (N2O), and conscious state to clarify influences of the anesthe
Externí odkaz:
https://doaj.org/article/72a95fc105ba49e4835642f087785c06
Autor:
Ai Goto, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kumiko Kitta, Kiyotaka Hoshiai, Koki Chiba, Kentaro Ando, Yasuki Akie, Atsuhiko T. Naito, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 138, Iss 3, Pp 198-202 (2018)
Although azithromycin can suppress cardiac INa, IKr, IKs, ICa,L and IK1, its onset mechanisms for cardiovascular death have not been fully investigated. We examined electropharmacological effects of azithromycin in intravenous doses of 0.3, 3 and 30
Externí odkaz:
https://doaj.org/article/dd24b26a681a444fa07908925ce40eac
Autor:
Kentaro Ando, Akira Takahara, Yuji Nakamura, Takeshi Wada, Koki Chiba, Ai Goto, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kiyotaka Hoshiai, Yasuki Akie, Atsuhiko T. Naito, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 2, Pp 86-92 (2018)
Microminipigs are expected as a novel animal model for cardiovascular pharmacological experiments. Since inherent vulnerability of coronary circulation of microminipigs has not been characterized, we performed dipyridamole-stress test to both micromi
Externí odkaz:
https://doaj.org/article/4b05046584de41e3bf9bae5a88804cd3
Autor:
Ai GOTO, Ryuichi KAMBAYASHI, Hiroyuki SAITO, Yasuki AKIE, Hiroko IZUMI-NAKASEKO, YoshinoriTAKEI, Atsushi SUGIYAMA
Publikováno v:
Journal of Veterinary Medical Science; 2023, Vol. 85 Issue 8, p828-831, 4p
Autor:
Akio Matsumoto, Ryuichi Kambayashi, Hiroyuki Saito, Atsushi Sugiyama, Yoshio Nunoi, Yoshinori Takei, Mihoko Hagiwara-Nagasawa, Yasuki Akie, Hiroko Izumi-Nakaseko, Kiyotaka Hoshiai, Ai Goto
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 3, Pp 268-272 (2021)
We assessed concentration-dependent effects of halothane or isoflurane inhalation on the electrocardiographic and hemodynamic variables using a cross-over design in intact beagle dogs (n = 4). Elevation of inhaled halothane from 1.0% to 2.0% or isofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09737895d308892ea994be33509616be
http://www.sciencedirect.com/science/article/pii/S1347861320301298
http://www.sciencedirect.com/science/article/pii/S1347861320301298
Autor:
Ryuichi Kambayashi, Hiroyuki Saito, Ai Goto, Yoshio Nunoi, Akio Matsumoto, Shinichi Kawai, Yoshinori Takei, Atsushi Sugiyama, Mihoko Hagiwara-Nagasawa, Yasuki Akie, Hiroko Izumi-Nakaseko, Kiyotaka Hoshiai
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 16-22 (2021)
We compared dl-sotalol-induced electrocardiographic responses in intact dogs using a repeated-measures design among 1% halothane anesthesia, 1.5% isoflurane anesthesia with nitrous oxide (N2O), and conscious state to clarify influences of the anesthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f3a82f047f66f1a4d5e5bb80ad9f44
https://doi.org/10.1016/j.jphs.2020.10.001
https://doi.org/10.1016/j.jphs.2020.10.001
Autor:
Atsushi Sugiyama, Yuji Nakamura, Yasuki Akie, Hiroyuki Saito, Yasukatsu Izumi, Hiroshi Yamazaki, Naoki Kaneko, Katzuhiko Itoh
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 2, Pp 122-126 (2011)
A new in vivo proarrhythmia model of drug-induced long QT syndrome was developed using the Microminipig, an incredibly small minipig established by Fuji Micra Inc. (Shizuoka). The atrioventricular (AV) node of the Microminipig of either sex weighing
Externí odkaz:
https://doaj.org/article/5d065e60d9d14a1a83c7b67913e707a6
Autor:
Akira Takahara, Hirotaka Wagatsuma, Shizuka Aritomi, Tomoyuki Konda, Yasuki Akie, Yuji Nakamura, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 132-135 (2011)
Abstract.: The chronic atrioventricular block (CAVB) dog has been widely used as an in vivo proarrhythmia model. mRNA levels of K+ and Ca2+ channels in the isolated ventricular tissues from normal and CAVB dogs were assayed using a real-time PCR. The
Externí odkaz:
https://doaj.org/article/65dac53524854aa7bd120c6b8212c0e8
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 473-486 (2005)
The purpose of this study was to assess the utility of the isoflurane-anesthetized dog model for detecting the potential for QT interval prolongation by human pharmaceuticals. The effects of 10 positive compounds with torsadogenic potential, 8 negati
Externí odkaz:
https://doaj.org/article/ed216b4d8f884d81a9ca95bda473f0d3