Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Yasukazu Takanezawa"'
Autor:
Yasukazu Takanezawa, Kouhei Ishikawa, Shunsuke Nakayama, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Methylmercury (MeHg) is converted to inorganic mercury (iHg) in several organs; however, its impact on tissues and cells remains poorly understood. Previously, we established a bacterial organomercury lyase (MerB)-expressing mammalian cell l
Externí odkaz:
https://doaj.org/article/0924477f8a7441d8ae00608f9ffebf48
Autor:
Shimpei Uraguchi, Yuka Ohshiro, Mayu Okuda, Shiho Kawakami, Nene Yoneyama, Yuta Tsuchiya, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
We aimed to efficiently enhance plant Hg(II) tolerance by the transgenic approach utilizing a bacterial mercury transporter MerC, an Arabidopsis mesophyll specific promoter pRBCS1A, and a vacuolar membrane targeting syntaxin AtVAM3/SYP22. We generate
Externí odkaz:
https://doaj.org/article/7fd0ba51ce9b430d92eeb8304e7dad70
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101217- (2022)
Gadolinium-based contrast agents (GBCAs) are widely used to improve tissue contrast during magnetic resonance imaging. Exposure to GBCAs can result in gadolinium deposition within human tissues and has become a clinical concern because of the potenti
Externí odkaz:
https://doaj.org/article/ff72167da76f45f0a013469516d6e8cf
Autor:
Shimpei Uraguchi, Yuka Ohshiro, Yuto Otsuka, Hikari Tsukioka, Nene Yoneyama, Haruka Sato, Momoko Hirakawa, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
For researchers in the plant metal field, the agar reagent used for the solid plate medium is a problematic factor because application of different agar types and even a different lot of the same agar type can mask the plant metal-related phenotypes
Externí odkaz:
https://doaj.org/article/292f4b0b7d874e8885b037280e7b4ad6
Autor:
Yasukazu Takanezawa, Ryosuke Nakamura, Ryohei Harada, Yuka Sone, Shimpei Uraguchi, Masako Kiyono
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Methylmercury (MeHg) is a widely distributed environmental pollutant that causes a series of cytotoxic effects. However, molecular mechanisms underlying MeHg toxicity are not fully understood. Here, we report that sequestosome1/p62 protects
Externí odkaz:
https://doaj.org/article/8c87fd45e2c347a38939627326fb4896
Autor:
Aya Kobayashi, Yasukazu Takanezawa, Takashi Hirata, Yuji Shimizu, Keiko Misasa, Noriyuki Kioka, Hiroyuki Arai, Kazumitsu Ueda, Michinori Matsuo
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 8, Pp 1791-1802 (2006)
Cholesterol and phospholipids are essential to the body, but an excess of cholesterol or lipids is toxic and a risk factor for arteriosclerosis. ABCG1, one of the half-type ABC proteins, is thought to be involved in cholesterol homeostasis. To explor
Externí odkaz:
https://doaj.org/article/72203585b073430091c59fe59d2d0b94
Autor:
Yasukazu Takanezawa1, Ryosuke Nakamura1, Yuka Ohshiro1, Shimpei Uraguchi1, Masako Kiyono1 kiyonom@pharm.kitasato-u.ac.jp
Publikováno v:
Journal of Toxicological Sciences. Jun2023, Vol. 48 Issue 6, p355-361. 7p.
Autor:
Shimpei Uraguchi1 uraguchis@pharm.kitasato-u.ac.jp, Yuka Ohshiro1, Kaede Abe1, Yuta Tsuchiya1, Ryosuke Nakamura1, Yasukazu Takanezawa1, Masako Kiyono1 kiyonom@pharm.kitasato-u.ac.jp
Publikováno v:
Soil Science & Plant Nutrition. Oct-Dec2023, Vol. 69 Issue 5/6, p294-302. 9p.
Autor:
Masako Kiyono, Yuka Ohshiro, Ryosuke Nakamura, Shimpei Uraguchi, Takuro Sugimoto, Yasukazu Takanezawa
Publikováno v:
Toxicology Letters. 353:93-99
Methylmercury (MeHg) is a hazardous environmental pollutant that causes serious toxicity in humans and animals, as well as proteotoxic stress. In our previous study, we found that MeHg induces the expression of p62/sequestosome 1 (p62) that selective
Autor:
Yuka Ohshiro, Arunee Wongkaew, Naoko Ohkama-Ohtsu, Ryosuke Nakamura, Fumii Naruse, Masako Kiyono, Kenichiro Nagai, Yuto Otsuka, Emiko Wada, Stephan Clemens, Shimpei Uraguchi, Kakeru Sugaya, Yasukazu Takanezawa
Publikováno v:
Plant Molecular Biology. 109:563-577
An organomercurial phenylmercury activates AtPCS1, an enzyme known for detoxification of inorganic metal(loid) ions in Arabidopsis and the induced metal-chelating peptides phytochelatins are essential for detoxification of phenylmercury. Small thiol-