Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Yasukazu HOZUMI"'
Autor:
Keiko Seino, Tomoyuki Nakano, Toshiaki Tanaka, Yasukazu Hozumi, Matthew K. Topham, Kaoru Goto, Ken Iseki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 2, Pp 300-308 (2024)
Expression of α‐smooth muscle actin (αSMA) is constitutive in vascular smooth muscle cells, but is induced in nonmuscle cells such as hepatic stellate cells (HSCs). HSCs play important roles in both physiological homeostasis and pathological resp
Externí odkaz:
https://doaj.org/article/3068bee3ba404d47bbc2cb2ea859d866
Autor:
Tomoyuki Nakano, Hirooki Matsui, Toshiaki Tanaka, Yasukazu Hozumi, Ken Iseki, Kaneyuki Kawamae, Kaoru Goto
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 4 (2016)
The endoplasmic reticulum (ER) comprises an interconnected membrane network, which is made up of lipid bilayer and associated proteins. This organelle plays a central role in the protein synthesis and sorting. In addition, it represents the synthetic
Externí odkaz:
https://doaj.org/article/1c4dbb06b35a4ca8aa38d603f160032c
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 3, Iss 1, Pp 38-49 (2008)
In this study, a new three-dimensional micro vibration stage is developed, in which a doubly steric L-shaped clamped-free beam type vibrator is utilized. The developed three-dimensional micro vibration stage, which has very simple structure and is qu
Externí odkaz:
https://doaj.org/article/c69db7fc482c4a79861eef0fbc60dcae
Publikováno v:
Biochemical and Biophysical Research Communications. 625:161-166
Activation of Gq protein-coupled receptors triggers the phospholipase C (PLC) pathway, which yields a pair of second messengers: diacylglycerol (DG) and inositol 1,4,5-trisphosphate (IP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16260a3875c05dde8849eb8e66a38779
https://doi.org/10.1016/j.bbrc.2022.07.118
https://doi.org/10.1016/j.bbrc.2022.07.118
Autor:
Masato Sano, Tomoyuki Nakano, Shinji Yamada, Yasukazu Hozumi, Yukinari Kato, Kaoru Goto, Toshiaki Tanaka, Satoshi Ogasawara, Mika K. Kaneko, Yusuke Sayama
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 38:179-182
Diacylglycerol kinase (DGK) is an enzyme that converts diacylglycerol (DG) to phosphatidic acid (PA). As both DG and PA serve as lipidic second messengers, DGK plays a pivotal role in controlling the balance of two signaling pathways mediated by DG a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c2af3b0dc74bcf2d71cfc4c120be70
https://doi.org/10.1089/mab.2019.0024
https://doi.org/10.1089/mab.2019.0024
Autor:
Kaoru Goto, Yasukazu Hozumi, Seiji Kakehata, Makoto Chiba, Hirooki Matsui, Tsukasa Ito, Chikako Shinkawa
Publikováno v:
Histochemistry and Cell Biology. 151:461-474
Cochlear hair cells are essential for the mechanotransduction of hearing. Sensorineural hearing loss can be irreversible because hair cells have a minimal ability to repair or regenerate themselves once damaged. In order to develop therapeutic interv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed0d3a4c469bc892a98ec0eadd7908e
https://doi.org/10.1007/s00418-019-01781-9
https://doi.org/10.1007/s00418-019-01781-9
Autor:
Tomonori Ayukawa, Masakazu Akiyama, Yasukazu Hozumi, Kenta Ishimoto, Junko Sasaki, Haruki Senoo, Takehiko Sasaki, Masakazu Yamazaki
Publikováno v:
Cell Reports. 40:111388
Planar cell polarity (PCP) regulates the orientation of external structures. A core group of proteins that includes Frizzled forms the heart of the PCP regulatory system. Other PCP mechanisms that are independent of the core group likely exist, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff9ae97dbe0e5a32d95ed7c6748a247
https://doi.org/10.1016/j.celrep.2022.111388
https://doi.org/10.1016/j.celrep.2022.111388
Diacylglycerol kinase (DGK) constitutes a family of enzymes that phosphorylate diacylglycerol to phosphatidic acid (PA). These lipids serve as second messengers, thereby activating distinct downstream cascades and different cellular responses. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4072cd85c5d99397ca4fbbb40bba0eab
http://hdl.handle.net/11585/827596
http://hdl.handle.net/11585/827596
Autor:
Tomoyuki Nakano, Satoshi Ogasawara, Toshiaki Tanaka, Yasukazu Hozumi, Atsumi Yamaki, Fumio Sakane, Yasuhito Shirai, Takuro Nakamura, Miyuki Yanaka, Shinji Yamada, Mika K. Kaneko, Yukinari Kato, Kaoru Goto
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 37:229-232
Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) to produce phosphatidic acid (PA). Since both DG and PA serve as lipidic second messengers, DGK plays a pivotal role in regulating the balance of two signaling pathways mediated by DG and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1507461fc1c3e1c2fae868be98ef023
https://doi.org/10.1089/mab.2018.0026
https://doi.org/10.1089/mab.2018.0026
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864:1759-1768
Nuclear factor-κB (NF-κB) participates in apoptosis signaling pathway under various pathophysiological conditions. It exerts transcriptional control on the anti-apoptotic Bcl-2 family, such as Bcl-2, Bcl-xl, and Mcl-1, which act on the mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c911833ce1381d6efc64db835ff44f
https://doi.org/10.1016/j.bbamcr.2017.06.021
https://doi.org/10.1016/j.bbamcr.2017.06.021