Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Yasuhito FUJINO"'
Autor:
Tomoyuki Harada, Daiki Kato, Masaya Tsuboi, Yasuhito Fujino, Hideyuki Kanemoto, Hajime Tsujimoto, Kazuyuki Uchida, Hiroyuki Nakayama, Kenjiro Fukushima, Koichi Ohno, Masashi Takahashi
Publikováno v:
Veterinary Clinical Pathology. 45:579-583
A 7-year-old Shetland Sheepdog was presented with anorexia. A CBC indicated thrombocytopenia and neutropenia. Bone marrow cytology revealed that 67.7% of all nucleated cells (ANC) were anaplastic large mononuclear cells. These cells were confirmed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d3c9153b0ec6d969d344664801848b
https://doi.org/10.1111/vcp.12420
https://doi.org/10.1111/vcp.12420
Autor:
Koichi Ohno, Masahiko Sato, Jumpei Yamazaki, Asuka Setoguchi, Yasuhito Fujino, Yuko Goto-Koshino, Masashi Takahashi, Kenji Baba, Hajime Tsujimoto
Publikováno v:
The Veterinary Journal. 215:38-42
Lymphoma is the most common haematopoietic malignancy in dogs. Since a high proportion of dogs with lymphoma achieve remission soon after initiation of chemotherapy, an objective marker assessing treatment efficacy is required. Following clinical rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7e787aad5dd997c5257311729a3566
https://doi.org/10.1016/j.tvjl.2016.05.012
https://doi.org/10.1016/j.tvjl.2016.05.012
Autor:
Saaya Hiyoshi-Kanemoto, Kenjiro Fukushima, Hajime Tsujimoto, Yuko Goto-Koshino, Masashi Takahashi, Koichi Ohno, Yasuhito Fujino, Kazuyuki Uchida, Hideyuki Kanemoto
Publikováno v:
The Journal of Veterinary Medical Science
The presence of circulating tumor cells (CTCs) serves as a prognostic marker and indicator of disease relapse, as well as a means of evaluating treatment efficacy in human and canine lymphoma patients. As an extension of our previous study for the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1caaf8e751df745dfb575ad385d3fcc9
https://doi.org/10.1292/jvms.15-0433
https://doi.org/10.1292/jvms.15-0433
Autor:
Tomoki Motegi, Koichi Ohno, Masashi Takahashi, Hirotaka Tomiyasu, Saaya Hiyoshi-Kanemoto, Yasuhito Fujino, Yuko Goto-Koshino, Hajime Tsuimoto
Publikováno v:
American journal of veterinary research. 79(9)
OBJECTIVE To determine the prognostic value of CD44 variant isoform expression in dogs with multicentric high-grade B-cell lymphoma (BCL). ANIMALS 45 dogs with multicentric BCL and 10 healthy control Beagles. PROCEDURES The medical record database of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd440cc48b2d60e213dd65a7918e0e5
https://pubmed.ncbi.nlm.nih.gov/30153061
https://pubmed.ncbi.nlm.nih.gov/30153061
Autor:
Hajime Tsujimoto, Yuko Goto-Koshino, Shingo Maeda, Yasuhito Fujino, Saaya Hiyoshi, Kazuyuki Uchida, Hiroyuki Mochizuki, Ko Nakashima, Koichi Ohno, Aki Fujiwara-Igarashi, Kenji Nakamura, Masahiko Sato
Publikováno v:
Veterinary Immunology and Immunopathology. 165:81-87
Polymerase chain reaction (PCR) amplification to detect immunoglobulin heavy chain (IgH) and T cell receptor γ-chain (TCRγ) gene rearrangements has recently become widely used as part of the diagnostic strategy for lymphoid tumors in dogs. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b999c432d964ae56be0581fb061776
https://doi.org/10.1016/j.vetimm.2015.03.005
https://doi.org/10.1016/j.vetimm.2015.03.005
Autor:
Hajime Tsujimoto, Yuko Goto-Koshino, Hirotaka Tomiyasu, Koichi Ohno, Hajime Asada, Yasuhito Fujino
Publikováno v:
The Journal of Veterinary Medical Science
Canine histiocytic sarcoma (HS) is an aggressive tumor type originating from histiocytic cell lineages. This disease is characterized by poor response to chemotherapy and short survival time. Therefore, it is of critical importance to identify and de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a673432a621e615cd25e76265bf95126
https://doi.org/10.1292/jvms.14-0415
https://doi.org/10.1292/jvms.14-0415
Autor:
Koichi Ohno, Hajime Tsujimoto, Aki Fujiwara-Igarashi, Yasuhito Fujino, Yuko Goto-Koshino, Hiroyuki Mochizuki, Masahiko Sato
Publikováno v:
Research in Veterinary Science. 97:60-63
To investigate the epigenetic regulation of the p16 gene in canine lymphoid tumor cells, its methylation status was examined in four canine lymphoid tumor cell lines. In three canine lymphoid tumor cell lines (CLBL-1, GL-1, and UL-1) with low-level p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc0af973d5a2ace4a943863b9aaabb0
https://doi.org/10.1016/j.rvsc.2014.04.008
https://doi.org/10.1016/j.rvsc.2014.04.008
Autor:
Hiyoshi Suzuki, Koichi Ohno, Yasuhito Fujino, Noriyuki Mizutani, Hirotaka Tomiyasu, Hajime Tsujimoto, Takashi Tamamoto, Yuko Goto-Koshino
Publikováno v:
Veterinary Immunology and Immunopathology. 160:118-122
CD45 is one of the most abundant molecules expressed on the white blood cell surface in various mammals. In this study, we investigated the differential expression of CD45 isoforms in normal canine white blood cells. It has been shown that all canine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07279c23b514fc3c33f1790a45f703fb
https://doi.org/10.1016/j.vetimm.2014.03.011
https://doi.org/10.1016/j.vetimm.2014.03.011
Publikováno v:
The Veterinary Journal. 201:83-90
Acquisition of multidrug resistance (MDR) is a common cause of treatment failure during chemotherapy for dogs with lymphoma (lymphosarcoma). Overexpression of P-glycoprotein (P-gp), encoded by the ABCB1 gene, is associated with MDR. Perifosine, an Ak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d806464bbc3b3bc0476773ab4ee7dc63
https://doi.org/10.1016/j.tvjl.2014.04.002
https://doi.org/10.1016/j.tvjl.2014.04.002
Autor:
Yasuhito Fujino, Hideyuki Kanemoto, Yuko Goto-Koshino, Kenjiro Fukushima, Hajime Tsujimoto, Masashi Takahashi, Ko Nakashima, Yasuyuki Endo, Koichi Ohno
Publikováno v:
The Journal of Veterinary Medical Science
Nimustine (ACNU) is an alkylating agent of the nitrosourea and can be an antineoplastic agent in dogs. But, there has been no report on its dose-limiting toxicity (DLT) in dogs. This study was a phase I dose-escalation clinical trial to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24306a113cd626dd011e06e7e89a22f
http://europepmc.org/articles/PMC4108775
http://europepmc.org/articles/PMC4108775