Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Yasuhito, Nannya"'
Autor:
Satoshi Kaito, Kazumasa Aoyama, Motohiko Oshima, Akiho Tsuchiya, Makiko Miyota, Masayuki Yamashita, Shuhei Koide, Yaeko Nakajima-Takagi, Hiroko Kozuka-Hata, Masaaki Oyama, Takao Yogo, Tomohiro Yabushita, Ryoji Ito, Masaya Ueno, Atsushi Hirao, Kaoru Tohyama, Chao Li, Kimihito Cojin Kawabata, Kiyoshi Yamaguchi, Yoichi Furukawa, Hidetaka Kosako, Akihide Yoshimi, Susumu Goyama, Yasuhito Nannya, Seishi Ogawa, Karl Agger, Kristian Helin, Satoshi Yamazaki, Haruhiko Koseki, Noriko Doki, Yuka Harada, Hironori Harada, Atsuya Nishiyama, Makoto Nakanishi, Atsushi Iwama
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, although their therapeutic effects have been unsatisfactory. Here we show that CRISPR-Cas9 screening reveals that knockout of topoisomerase 1-binding argin
Externí odkaz:
https://doaj.org/article/d5c4ccd82b76400cb577a39dab027bde
Autor:
Yui Niiyama‐Uchibori, Shinsuke Mizutani, Taku Tsukamoto, Haruya Okamoto, Daisuke Ide, Akio Onishi, Daishi Kato, Takahiro Fujino, Yuji Shimira, Aya Miyagawa‐Hayashino, Eiichi Konishi, Kennosuke Karube, Yasuhito Nannya, Junya Kuroda
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 798-801 (2024)
Abstract In ALK‐negative anaplastic large cell lymphoma (ALCL), gene rearrangements of DUSP22 and TP63 are considered mutually exclusive. The former predicts a favorable prognosis, while the latter is generally unfavorable. We report the first case
Externí odkaz:
https://doaj.org/article/d6c191da8c874987bff4280cefb003d4
Autor:
Kosuke Takano, Maki Monna-Oiwa, Masamichi Isobe, Seiko Kato, Satoshi Takahashi, Yasuhito Nannya, Takaaki Konuma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Although daily higher urinary sodium (Na) and potassium (K) excretion ratio is associated with the risk of cardiovascular disease in the general population, a low Na/K ratio is associated with renal dysfunction in critically ill patients. Th
Externí odkaz:
https://doaj.org/article/da579cdb9f1e4104aedc02d4cf039936
Autor:
Yusuke Daido, Hiroyuki Sugiura, Tatsunori Ishikawa, Taiga Kuroi, Sachiyo Okamoto, Naho Nomura, Taro Masunari, Nobuo Sezaki, Yasuhito Nannya, Seishi Ogawa, Mitsune Tanimoto
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 999-1006 (2023)
Venetoclax and azacitidine combination therapy (VEN+AZA) is a promising novel therapy for elderly or unfit patients with acute myeloid leukemia (AML). Recently, VEN+AZA with subsequent allo-hematopoietic stem cell transplantation has been reported, a
Externí odkaz:
https://doaj.org/article/82eb6e7f3dbb47e49f5bfcaf6e14197d
Autor:
Tatsuya Imi, Hiroki Mizumaki, Kazuyoshi Hosomichi, Yasuhito Nannya, Yoshitaka Zaimoku, Takeshi Yoroidaka, Takamasa Katagiri, Ken Ishiyama, Hirohito Yamazaki, Ryosuke Ogawa, Mika Kuroiwa, Atsushi Tajima, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 714-718 (2023)
Abstract We studied the pathophysiology of aplastic anaemia (AA) in six different pairs of relatives without a family history of hematologic disorders or congenital AA. Five and four of the six pairs shared the HLA‐DRB1*15:01 and B*40:02 alleles, r
Externí odkaz:
https://doaj.org/article/7e00c78c4c74405dae8a50cc6975fa8e
Autor:
Tomohiko Yamada, Nobuhiro Hiramoto, Takuto Mori, Daisuke Yamashita, Yukimasa Tai, Ryusuke Yamamoto, Masashi Nishikubo, Hayato Maruoka, Kana Sakamoto, Kengo Takeuchi, Yasuhito Nannya, Seishi Ogawa, Takayuki Ishikawa
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/3050194baa724f22a730baa3ec07fc42
Autor:
Shinichi Ogawa, Tatsuhiro Sakamoto, Ryota Matsuoka, Kantaro Ishitsuka, Yasuko Ogino, Ayano Sootome, Kenichi Makishima, Chikashi Yoshida, Yufu Ito, Seiichi Shimizu, Takuya Suyama, Atsushi Shinagawa, Takayoshi Ito, Naoshi Obara, Manabu Kusakabe, Mamiko Sakata‐Yanagimoto, Yasushi Miyazaki, Yasuhito Nannya, Shigeru Chiba
Publikováno v:
Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Hypomethylating agents, including azacytidine (AZA), are standard therapeutics for patients with high‐risk myelodysplastic syndromes (MDS), a group of myeloid neoplasms. However, treatment schedules are not unified in real‐wor
Externí odkaz:
https://doaj.org/article/f09fa49297404012bf6c2f22d92a991c
Autor:
Naoki Shingai, Hiroki Mizumaki, Yuho Najima, Yuta Yamada, Dung Cao Tran, Kyoko Haraguchi, Takashi Toya, Yoshiki Okuyama, Noriko Doki, Yasuhito Nannya, Seishi Ogawa, Shinji Nakao
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionParoxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disease characterized by intravascular hemolysis, thrombosis, and bone marrow (BM) failure. Although PNH is caused by excessive proliferation of hematopoietic stem cell (HS
Externí odkaz:
https://doaj.org/article/93462ae83a1f4d9495de2376385a73ff
Autor:
Koji Jimbo, Makoto Yamagishi, Yutaka Suzuki, Kako Suzuki, Motoko Mizukami, Kazuaki Yokoyama, Aki Sato, Tokiko Nagamura‐Inoue, Yasuhito Nannya, Kaoru Uchimaru
Publikováno v:
eJHaem, Vol 4, Iss 4, Pp 1188-1190 (2023)
Externí odkaz:
https://doaj.org/article/3cd168b09714405b9ffe2283a2a564ed
Autor:
Yuta Kaito, Emi Sugimoto, Fumi Nakamura, Yutaka Tsukune, Makoto Sasaki, Shunsuke Yui, Hiroki Yamaguchi, Susumu Goyama, Yasuhito Nannya, Kinuko Mitani, Hideto Tamura, Yoichi Imai
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Acute myeloid leukemia (AML) is a hematologic malignancy that frequently relapses, even if remission can be achieved with intensive chemotherapy. One known relapse mechanism is the escape of leukemic cells from immune surveillance. Currently, there i
Externí odkaz:
https://doaj.org/article/3560553c000846369e1641d594303952