Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yasuhisa Imai"'
Publikováno v:
British Journal of Ophthalmology. 90:765-768
Background/aims: Chemokines are key molecules that initiate leucocyte infiltration to the inflammatory site. The involvement of chemokines in uveitis is well studied, yet the source of this molecule in the inflamed eye is not clearly identified. The
Autor:
Kyogo Itoh, Toshihiro Imaizumi, Tomoaki Hoshino, Masashi Gotoh, Takashi Yamaoka, Shigeki Shichijo, Yasuhisa Imai, Yoshiko Inoue, Hideo Takasu
Publikováno v:
Japanese Journal of Cancer Research : Gann
Human SART-1 (hSART-1) gene encodes a 125 kD protein with a leucine-zipper motif expressed in the nucleus of all proliferating cells, and a 43 kD protein expressed in the cytosol of most epithelial cancers. In this study, two rodent genes (rSART-1 an
Autor:
Hideaki Yamana, Kyogo Itoh, Shigeki Shichijo, Damu Yang, Mayumi Kawamoto, Masanobu Nakao, Yuji Toh, Fumihiko Niiya, Hideo Takasu, Yasuhisa Imai
Publikováno v:
The Journal of Experimental Medicine
Except for melanomas, tumor antigens recognized by cytotoxic T lymphocytes (CTLs) are yet unidentified. We have identified a gene encoding antigenic peptides of human squamous cell carcinomas (SCCs) recognized by human histocompatibility leukocyte an
Autor:
Kyogo Itoh, Uhi Toh, Kazuo Shirouzu, Hiromasa Fujita, Masanobu Nakao, Yasuhisa Imai, Toshihiko Kaneshige, Naoko Seki, Hideo Takasu, Hideaki Yamana
Publikováno v:
Cellular Immunology. 177:137-143
This paper investigates the presence of HLA class I-restricted and tumor-specific cytotoxic T lymphocytes (CTL) in tumor sites of esophageal cancers. Five CTL lines were established from the metastatic lymph nodes or pleural effusion by incubation wi
Publikováno v:
Cellular Immunology. 166:254-260
We previously reported that the immunohistochemically defined LFA-1 antigen (LFA-1-like antigen) was expressed on various exocrine tissues uninvolved with tumors in patients with malignant diseases using LFA-1 alpha-specific monoclonal antibodies (mA
Autor:
Kazuhito Tamehiro, Eiki Tayama, Kyogo Itoh, Masanori Ohashi, Yasuhisa Imai, Tadashi Isomura, Kenichi Kosuga, Kouichi Hisatomi, Tohru Sato, Kiroku Ohishi
Publikováno v:
Surgery Today. 25:145-150
The inhibitory effect of ongoing rejection and the changes that occurred in mononuclear cell subpopulations were compared between four groups of rats treated with FK506 or steroids. Group 1 was given no immunosuppressive drugs, group 2 was given FK50
Publikováno v:
Gene. 160:287-290
The MAGE multigene family, which includes the MAGE-1 and -3 genes that encode tumor-rejection antigens on HLA-A1 recognized by cytotoxic T-lymphocytes (CTL), is preferentially expressed at the mRNA level on human malignant cells, but not on normal ce
Autor:
Chikako Taguchi, Hiroshi Takase, Tatsushi Kawaguchi, Yuri Futagami, Koju Kamoi, Sunao Sugita, Yoshiharu Sugamoto, Yasuhisa Imai, Manabu Mochizuki, Kyogo Itoh
Publikováno v:
Investigative ophthalmologyvisual science. 47(6)
PURPOSE. To determine whether patients with Vogt-Koyanagi-Harada (VKH) disease have immune responses specific to the melanocyte antigens tyrosinase and gp100. METHODS. T-cell clones (TCCs) were established from cells infiltrating the aqueous humor an
Autor:
Yuri Futagami, Tomoko Yoshida, Manabu Mochizuki, Yasuhisa Imai, Hiroshi Takase, Sunao Sugita, Koju Kamoi
Publikováno v:
Investigative ophthalmologyvisual science. 47(4)
Purpose To determine the cytokine expression profile at the protein level in aqueous humor (AqH) and sera of patients with uveitis. Methods Patients with various clinical entities of strictly diagnosed infectious or noninfectious uveitis were tested.
Autor:
Hiroshi, Takase, Sunao, Sugita, Douglas J, Rhee, Yasuhisa, Imai, Chikako, Taguchi, Yoshiharu, Sugamoto, Yoshitsugu, Tagawa, Jun, Nishihira, Paul, Russell, Manabu, Mochizuki
Publikováno v:
Investigative ophthalmologyvisual science. 43(8)
To investigate the expression and secretion of macrophage migration inhibitory factor (MIF) in human trabecular meshwork (HTM) and evaluate its role in ocular inflammation.Tissue samples of HTM cells were isolated from donor human eyes or corneoscler