Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Yasuhisa Fukui"'
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125054 (2015)
The MEK/ERK pathways are critical for controlling cell proliferation and differentiation. In this study, we show that the MEK5/ERK5 pathway participates in osteoclast differentiation. ERK5 was activated by M-CSF, which is one of the essential factors
Externí odkaz:
https://doaj.org/article/98359c35b1154f599b342febcac38317
Autor:
Ching-Yu Lin, Chieh Huo, Li-Kuo Kuo, Richard A Hiipakka, Richard Baker Jones, Hui-Ping Lin, Yuwen Hung, Liang-Cheng Su, Jen-Chih Tseng, Ying-Yu Kuo, Yu-Ling Wang, Yasuhisa Fukui, Yung-Hsi Kao, John M Kokontis, Chien-Chih Yeh, Linyi Chen, Shiaw-Der Yang, Hsiao-Hui Fu, Ya-Wen Chen, Kelvin K C Tsai, Jang-Yang Chang, Chih-Pin Chuu
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65734 (2013)
Oxysterols are oxidation products of cholesterol. Cholestane-3β, 5α, 6β-triol (abbreviated as triol) is one of the most abundant and active oxysterols. Here, we report that triol exhibits anti-cancer activity against human prostate cancer cells. T
Externí odkaz:
https://doaj.org/article/a2750f48587249f5af8b00ca39e2effd
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59245 (2013)
SWAP-70 is a protein that has been suggested to be involved in regulation of actin rearrangement. Having discovered that an artificially-derived mutant of SWAP-70 can transform mouse embryo fibroblasts, we searched for naturally-occurring mutations i
Externí odkaz:
https://doaj.org/article/9548617774e94c379540dec5a130bba4
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53298 (2013)
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent p
Externí odkaz:
https://doaj.org/article/040ef11b836d45b9b239f7c9853a70f9
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29599 (2011)
Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated adeno
Externí odkaz:
https://doaj.org/article/79ca4d8e843e4a779749a359d09e2831
Autor:
Yasuhisa Fukui, Sayoko Ihara
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14180 (2010)
SWAP-70, a phosphatidylinositol trisphosphate (PtdIns(3,4,5)P(3)) binding protein, has been suggested to be involved in transformation of mouse embryo fibroblasts (MEFs) as well as membrane ruffling after growth factor stimulation of the cells. A mut
Externí odkaz:
https://doaj.org/article/177dea379c1847b0bdd1f64867956b45
Autor:
Jing-Yang Lai, Rolf Jessberger, Chih-Pin Chuu, Yu-Tzu Chang, Chung-Li Shu, Kazuhiro Morishita, Tomonaga Ichikawa, Yasuhisa Fukui, Ching-Yu Lin
Publikováno v:
Experimental Cell Research. 345:150-157
Mouse embryo fibroblasts (MEFs) grow slowly after cultivation from animals, however, after an extended period of cultivation, their growth accelerates. We found that SWAP-70 deficient MEFs failed to increase growth rates. They maintain normal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27d39211a53aa4c0df063a585b36fa4
https://doi.org/10.1016/j.yexcr.2015.06.011
https://doi.org/10.1016/j.yexcr.2015.06.011
Publikováno v:
CellBio. :87-95
Raw264.7 cells are monocytic cells that can differentiate to activated macrophages after lipopoly-saccharide (LPS) stimulation. Here, we analyzed the factors secreted by Raw264.7 cells in response to LPS. The culture media of LPS-treated Raw264.7 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112abbfa6acbfc2d86a380e417824bab
https://doi.org/10.4236/cellbio.2014.33009
https://doi.org/10.4236/cellbio.2014.33009
Publikováno v:
Biochemical and Biophysical Research Communications. 433:311-316
Rac1 is important for dissociation of cells during scattering, but whether its activation alone is sufficient to induce complete scattering is not known. To test this, we created an inducible MCF7 cell line that expresses dominant active Rac1. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7953e6f012cf1c30c89060b3255942c8
https://doi.org/10.1016/j.bbrc.2013.02.103
https://doi.org/10.1016/j.bbrc.2013.02.103
Autor:
Yasuhisa Fukui
Publikováno v:
Biochemical and Biophysical Research Communications. 450:1231-1233
Signet ring cell carcinomas are highly malignant dedifferentiated adenocarcinomas. There are no cell-cell interactions between these round-shaped cells. They contain huge numbers of vacuoles, filled with mucins, which are secreted from the cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6523e23b64031008027632a310ec99b9
https://doi.org/10.1016/j.bbrc.2014.07.025
https://doi.org/10.1016/j.bbrc.2014.07.025