Zobrazeno 1 - 10
of 778
pro vyhledávání: '"Yasuhiro. Takeuchi"'
Autor:
Leila Mekkaoui, Farhaan Parekh, Ekaterini Kotsopoulou, David Darling, Glenda Dickson, Gordon W. Cheung, Lucas Chan, Kirsty MacLellan-Gibson, Giada Mattiuzzo, Farzin Farzaneh, Yasuhiro. Takeuchi, Martin Pule
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss , Pp 155-165 (2018)
Lentiviral vectors (LVs) have recently witnessed an increasing demand in research and clinical applications. Their current purification processes represent the main bottleneck in their widespread use, as the methods used are cumbersome and yield low
Externí odkaz:
https://doaj.org/article/fa0e0c7804034ed983ca5258b74e7dce
Publikováno v:
Infectious Disease Modelling, Vol 9, Iss 2, Pp 483-500 (2024)
Preventive treatment for people with latent Tuberculosis infection (LTBI) has aroused our great interest. In this paper, we propose and analyze a novel mathematical model of TB considering preventive treatment with media impact. The basic reproductio
Externí odkaz:
https://doaj.org/article/61faf6a39070426e8a516c442697fc1d
Autor:
Dale J. Stibbs, Pedro Silva Couto, Yasuhiro Takeuchi, Qasim A. Rafiq, Nigel B. Jackson, Andrea C.M.E. Rayat
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101264- (2024)
Quasi-perfusion culture was employed to intensify lentiviral vector (LV) manufacturing using a continuous stable producer cell line in an 8-day process. Initial studies aimed to identify a scalable seeding density, with 3, 4, and 5 × 104 cells cm−
Externí odkaz:
https://doaj.org/article/a2f19cde90514fd29c9d3b23d60c622c
Autor:
Dale J. Stibbs, Pedro Silva Couto, Yasuhiro Takeuchi, Qasim A. Rafiq, Nigel B. Jackson, Andrea C.M.E. Rayat
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101209- (2024)
Continuous manufacturing of lentiviral vectors (LVs) using stable producer cell lines could extend production periods, improve batch-to-batch reproducibility, and eliminate costly plasmid DNA and transfection reagents. A continuous process was establ
Externí odkaz:
https://doaj.org/article/9a07beca55a94568a5587afb1f9acd79
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 6, Pp 11000-11032 (2023)
A delay differential equation model of an infectious disease is considered and analyzed. In this model, the impact of information due to the presence of infection is considered explicitly. As information propagation is dependent on the prevalence of
Externí odkaz:
https://doaj.org/article/6c554116bea74f43aa78d9646ba2a06f
Autor:
Yu Liu, Yuhang Ma, Cuihong Yang, Zhihang Peng, Yasuhiro Takeuchi, Malay Banerjee, Yueping Dong
Publikováno v:
Symmetry, Vol 16, Iss 6, p 676 (2024)
Tumor–immune system interactions are very complicated, being highly nonlinear and not well understood. A large number of tumors can potentially weaken the immune system through various mechanisms such as secreting cytokines that suppress the immune
Externí odkaz:
https://doaj.org/article/40c910f199274c1fb556de8490afde6a
Autor:
Keita Tatsushima, Akira Takeshita, Shuji Fukata, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Hiroshi Nishioka, Yasuhiro Takeuchi
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2021)
A 50-year-old woman with thyroid-stimulating hormone (TSH)-producing pituitary adenoma (TSHoma) was diagnosed due to symptoms of thyrotoxicosis. Preoperatively, she showed thyrotoxicosis with the syndrome of inappropriate secretion of TSH (SITSH) and
Externí odkaz:
https://doaj.org/article/1b44e1f8b34b48c38bf0853f3d8fd9d5
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 1, Pp 583-599 (2021)
In the present research, we study a mathematical model for vector-borne plant disease with the plant resistance to disease and vector crowding effect and propose using Beddington-DeAngelis type disease transmission and incubation delay. Existence and
Externí odkaz:
https://doaj.org/article/74a3a02c973e4d9db6677830364d94ab
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 2, Pp 1450-1464 (2021)
In this article, we have presented a mathematical model to study the dynamics of hepatitis C virus (HCV) disease considering three populations namely the uninfected liver cells, infected liver cells, and HCV with the aim to control the disease. The m
Externí odkaz:
https://doaj.org/article/7dbb8a2beddb4992ac5ae94a04a4b3bf
Autor:
Yasuhiro Takeuchi
Publikováno v:
Osteoporosis and Sarcopenia, Vol 7, Iss 3, Pp 89-91 (2021)
Romosozumab is a potent pharmacological tool to prevent fractures in osteoporosis patients, and its mechanism of action is distinct from any other drugs. The efficacy of romosozumab to prevent osteoporotic fractures is remarkable. However, there rema
Externí odkaz:
https://doaj.org/article/2344719fefc64e399e7fb77a70f1fb24