Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yasuhiro Tateishi"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9020 (2024)
Cytochrome P450 (P450) enzymes dominate steroid metabolism. In general, the simple C-hydroxylation reactions are mechanistically straightforward and are generally agreed to involve a perferryl oxygen species (formally FeO3+). Several of the steroid t
Externí odkaz:
https://doaj.org/article/360b5c5b8f9b41ccb18e32215ad5370d
Autor:
Yasuhiro Tateishi, Tomoyuki Ohe, Mai Ogawa, Kyoko Takahashi, Shigeo Nakamura, Tadahiko Mashino
Publikováno v:
ACS Omega, Vol 5, Iss 50, Pp 32608-32616 (2020)
Externí odkaz:
https://doaj.org/article/6d7d60ef6cb344298d627907713488a5
Autor:
Yasuhiro Tateishi1, Webb, Stephany N.1, Bian Li2, Lu Liu1, Rose, Kristie Lindsey1,3, Leser, Micheal3, Patel, Purvi3, Guengerich, F. Peter1 f.guengerich@vanderbilt.edu
Publikováno v:
Journal of Biological Chemistry. Mar2024, Vol. 300 Issue 3, p1-15. 15p.
Publikováno v:
Medicinal Chemistry Research.
Publikováno v:
Drug Metabolism and Disposition. 49:902-909
Numerous studies have been reported in the past 50-plus years regarding the stimulatory role of cytochrome b5 (b5) in some but not all microsomal cytochrome P450 (P450, CYP) reactions with drugs and steroids. A missing element in most of these studie
Autor:
Kevin D. McCarty, Molly E. Sullivan, Yasuhiro Tateishi, Tatiana Y. Hargrove, Galina I. Lepesheva, F. Peter Guengerich
Publikováno v:
Journal of Biological Chemistry. :104841
Autor:
Kyoko Takahashi, Tomoyuki Ohe, Daisuke Yasuda, Shigeo Nakamura, Yasuhiro Tateishi, Tadahiko Mashino, Yasuhiro Kazuki
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:238-243
Nevirapine (NVP) is widely used as a non-nucleoside reverse transcriptase inhibitor of HIV-1, however, it is associated with severe skin and liver injury. The mechanisms of these adverse reactions are not yet clear, but the metabolic activation of NV
Autor:
Yasuhiro Tateishi, Chikako Shibazaki, Kyoko Takahashi, Shigeo Nakamura, Yasuhiro Kazuki, Tadahiko Mashino, Tomoyuki Ohe
Publikováno v:
Drug metabolism and pharmacokinetics. 43
Tofacitinib (TFT), a JAK inhibitor used for the treatment of rheumatoid arthritis and other diseases, is associated with severe liver injury that is believed to be caused by its reactive aldehyde or epoxide metabolites. In this study, we synthesized
Publikováno v:
Drug Metab Dispos
Numerous studies have been reported in the past 50-plus years regarding the stimulatory role of cytochrome b(5) (b(5)) in some, but not all, microsomal cytochrome P450 (P450) reactions with drugs and steroids. A missing element in most of these studi