Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Yasuhiro Miki"'
Autor:
Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, Kazuyuki Kitatani
Publikováno v:
Cells, Vol 13, Iss 5, p 405 (2024)
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic agents, induce necroptosis by targeting the activating protein mixed lineage
Externí odkaz:
https://doaj.org/article/25245639c9bc45fd9cd5ba12f6ade3db
Publikováno v:
Endocrine Oncology, Vol 2, Iss 1, Pp R132-R142 (2023)
In hormone-dependent cancers, the activation of hormone receptors promotes the progression of cancer cells. Many proteins exert their functions through protein– protein interactions (PPIs). Moreover, in such cancers, hormone–hormone receptor bind
Externí odkaz:
https://doaj.org/article/7e02d1fd19c64cbab5f520d9bfe75e17
Autor:
Takehiro Yamada, Yasuhiro Miki, Miho Suzuki, Osamu Kondoh, Ryoko Saito‐Koyama, Katsuhiko Ono, Yoshinori Okada, Hironobu Sasano
Publikováno v:
Cancer Medicine, Vol 11, Iss 2, Pp 479-491 (2022)
Abstract Background Programmed cell death ligand 1 (PD‐L1) status has been reported to be different between metastatic and primary lesions in some cases. Therefore, the interaction between carcinoma and immune cells could influence their expression
Externí odkaz:
https://doaj.org/article/8a794d7d86b441d9a01417c384abf3f0
Publikováno v:
Cancers, Vol 15, Iss 14, p 3620 (2023)
The importance of sex hormones, especially estrogen, in the pathogenesis of non-small-cell lung cancer (NSCLC) has attracted attention due to its high incidence among young adults and nonsmokers, especially those who are female. Cancer-associated fib
Externí odkaz:
https://doaj.org/article/3eb519535b194797a26d32ae34732be3
Autor:
Yasuhiro Miki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10830 (2023)
Hormones, especially steroids, are closely involved in the physiological functions and proliferation of various target tissues and have long been known to play a key role in the tumorigenesis or carcinogenesis of these target tissues [...]
Externí odkaz:
https://doaj.org/article/9b56d2139dac46869123de5dfbe14c9c
Autor:
Ai Sato, Kiyoshi Takagi, Ayano Yoshimura, Wakana Tsukamoto, Mio Yamaguchi-Tanaka, Yasuhiro Miki, Akiko Ebata, Minoru Miyashita, Takashi Suzuki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8419 (2023)
Kallikrein-related peptides (KLKs) form an evolutionally conserved subgroup of secreted serine proteases that consists of 15 members (KLK1-15). Previous studies have shown that KLKs regulate diverse biological processes, but the clinical significance
Externí odkaz:
https://doaj.org/article/4250b1c43fee4418b09cb37b9308c41b
Autor:
Mio Yamaguchi-Tanaka, Kiyoshi Takagi, Yasuhiro Miki, Ai Sato, Erina Iwabuchi, Minoru Miyashita, Takashi Suzuki
Publikováno v:
Cancers, Vol 15, Iss 6, p 1903 (2023)
Tumor-associated macrophages (TAMs) contribute to tumor progression and chemoresistance; it is therefore important to clarify the altered functions of macrophages following chemotherapy. While extracellular heat shock protein (HSP) 70 is associated w
Externí odkaz:
https://doaj.org/article/a3cdae09f957412c9390079df079f5c4
Autor:
Sachiko Kawana, Ryoko Saito, Yasuhiro Miki, Yuichiro Kimura, Jiro Abe, Ikuro Sato, Mareyuki Endo, Shunichi Sugawara, Hironobu Sasano
Publikováno v:
Cancer Medicine, Vol 10, Iss 2, Pp 718-727 (2021)
Abstract Immunotherapy is considered one of the most important therapeutic strategies for patients with lung adenocarcinoma after the development of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) resistance. However, useful p
Externí odkaz:
https://doaj.org/article/af90d242273c44e78e091062c18d8c30
Publikováno v:
Progress in Disaster Science, Vol 8, Iss , Pp 100128- (2020)
The environment surrounding researchers has changed significantly in the face of COVID-19 restrictions. An online self-reported questionnaire was completed by 10,557 participants between June 15 and 19, 2020. The impact on work/research activities an
Externí odkaz:
https://doaj.org/article/479ed318857d4475afaea51d44e7b3a3
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229924 (2020)
After disasters, issues pertaining to women's health such as irregular periods and bleeding are well surveyed. However, the management of women's health, especially changes in the rate of health checkups, has not been investigated. In the present stu
Externí odkaz:
https://doaj.org/article/c3df7806f5ed442cb0148eebdd2a6bd9