Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Yasuhiro MIKI"'
Autor:
Nattaya Duangthim, Thanpisit Lomphithak, Ryoko Saito-Koyama, Yasuhiro Miki, Chihiro Inoue, Ikuro Sato, Eisaku Miyauchi, Jiro Abe, Hironobu Sasano, Siriporn Jitkaew
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Lung cancer remains the leading cause of cancer death. Treatment with immune checkpoint inhibitor (ICI) alone or combination with chemotherapy served as first-line therapy in non-small cell lung cancer (NSCLC). However, only 20–50% of NSCL
Externí odkaz:
https://doaj.org/article/1ce6124ece9c48e5b0eda25e78fa7ddd
Publikováno v:
Endocrine Oncology, Vol 4, Iss 1, Pp 1-12 (2024)
Elucidating the mechanisms of action of steroid hormones will contribute to the development of therapeutic strategies for hormone-dependent tumors. Recent advances in genetic engineering have revealed the complex and diverse mechanisms of steroid hor
Externí odkaz:
https://doaj.org/article/f9dc0626a11547ee8d00bbd7888b4209
Autor:
Satoshi Katano, Kotaro Yamano, Toshiyuki Yano, Ryo Numazawa, Ryohei Nagaoka, Suguru Honma, Yusuke Fujisawa, Yasuhiro Miki, Yuhei Takamura, Hayato Kunihara, Hiroya Fujisaki, Hidemichi Kouzu, Katsuhiko Ohori, Masaki Katayose, Akiyoshi Hashimoto, Masato Furuhashi
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 29, Iss 1, Pp 100434- (2025)
Objectives: The utility of the updated Asian Working Group for Sarcopenia (AWGS) criteria in diagnosing sarcopenia in older patients with heart failure (HF) remains unclear. Objective: To analyze the prevalence and prognostic impact of sarcopenia dia
Externí odkaz:
https://doaj.org/article/d8746efcbd7b486dace54bac57facc06
Autor:
Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, Kazuyuki Kitatani
Publikováno v:
Cells, Vol 13, Iss 5, p 405 (2024)
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic agents, induce necroptosis by targeting the activating protein mixed lineage
Externí odkaz:
https://doaj.org/article/25245639c9bc45fd9cd5ba12f6ade3db
Autor:
Takehiro Yamada, Yasuhiro Miki, Miho Suzuki, Osamu Kondoh, Ryoko Saito‐Koyama, Katsuhiko Ono, Yoshinori Okada, Hironobu Sasano
Publikováno v:
Cancer Medicine, Vol 11, Iss 2, Pp 479-491 (2022)
Abstract Background Programmed cell death ligand 1 (PD‐L1) status has been reported to be different between metastatic and primary lesions in some cases. Therefore, the interaction between carcinoma and immune cells could influence their expression
Externí odkaz:
https://doaj.org/article/8a794d7d86b441d9a01417c384abf3f0
Publikováno v:
Endocrine Oncology, Vol 2, Iss 1, Pp R132-R142 (2023)
In hormone-dependent cancers, the activation of hormone receptors promotes the progression of cancer cells. Many proteins exert their functions through protein– protein interactions (PPIs). Moreover, in such cancers, hormone–hormone receptor bind
Externí odkaz:
https://doaj.org/article/7e02d1fd19c64cbab5f520d9bfe75e17
Autor:
Sachiko Kawana, Ryoko Saito, Yasuhiro Miki, Yuichiro Kimura, Jiro Abe, Ikuro Sato, Mareyuki Endo, Shunichi Sugawara, Hironobu Sasano
Publikováno v:
Cancer Medicine, Vol 10, Iss 2, Pp 718-727 (2021)
Abstract Immunotherapy is considered one of the most important therapeutic strategies for patients with lung adenocarcinoma after the development of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) resistance. However, useful p
Externí odkaz:
https://doaj.org/article/af90d242273c44e78e091062c18d8c30
Publikováno v:
Progress in Disaster Science, Vol 8, Iss , Pp 100128- (2020)
The environment surrounding researchers has changed significantly in the face of COVID-19 restrictions. An online self-reported questionnaire was completed by 10,557 participants between June 15 and 19, 2020. The impact on work/research activities an
Externí odkaz:
https://doaj.org/article/479ed318857d4475afaea51d44e7b3a3
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229924 (2020)
After disasters, issues pertaining to women's health such as irregular periods and bleeding are well surveyed. However, the management of women's health, especially changes in the rate of health checkups, has not been investigated. In the present stu
Externí odkaz:
https://doaj.org/article/c3df7806f5ed442cb0148eebdd2a6bd9
Autor:
Minako Sakurai, Yasuhiro Miki, Kiyoshi Takagi, Takashi Suzuki, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-12 (2017)
Abstract Background Breast adipocytes play important roles in both the development and function of mammary epithelial cells. Therefore, carcinoma–adipose stromal cell (ASC) interactions have been considered pivotal in supporting tumor growth in bre
Externí odkaz:
https://doaj.org/article/a9ef25037ee94f0b8757cfe9f0a56cc7