Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yasuhiro Izumiyama"'
Autor:
Yoichi Kakuta, Takeru Nakano, Takeo Naito, Kazuhiro Watanabe, Yasuhiro Izumiyama, Daisuke Okamoto, Ryo Ichikawa, Rintaro Moroi, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Hisashi Shiga, Takeshi Naitoh, Yoshitaka Kinouchi, Michiaki Unno, Atsushi Masamune
Publikováno v:
JGH Open, Vol 4, Iss 4, Pp 624-631 (2020)
Background and Aim The T‐cell receptor (TCR) repertoire was assessed in response to various antigens and was considered to be associated with the pathogenesis of inflammatory bowel disease (IBD). Thus, we performed TCR repertoire analysis to examin
Externí odkaz:
https://doaj.org/article/46bb4256a5fc478d8ec5501f32c5ef0e
Autor:
Ryo Ichikawa, Masatake Kuroha, Tomoya Kimura, Hisashi Shiga, Yoshitake Kanazawa, Takeshi Naitoh, Yoichi Kakuta, Michiaki Unno, Kazuhiro Watanabe, Takeo Naito, Yasuhiro Izumiyama, Atsushi Masamune, Takeru Nakano, Rintaro Moroi, Yoshitaka Kinouchi, Daisuke Okamoto
Publikováno v:
JGH Open, Vol 4, Iss 4, Pp 624-631 (2020)
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
Background and Aim The T‐cell receptor (TCR) repertoire was assessed in response to various antigens and was considered to be associated with the pathogenesis of inflammatory bowel disease (IBD). Thus, we performed TCR repertoire analysis to examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88420cbbc315d6338e4c493283c1a00d
https://doaj.org/article/46bb4256a5fc478d8ec5501f32c5ef0e
https://doaj.org/article/46bb4256a5fc478d8ec5501f32c5ef0e
Autor:
Katsushi Tokunaga, Yuta Fuyuno, Yosuke Kawai, Hisashi Shiga, Yoshitaka Kinouchi, Tomoya Kimura, Rintaro Moroi, Takeo Naito, Takayuki Matsumoto, Akihiro Asakura, Masao Nagasaki, Atsushi Masamune, Masatake Kuroha, Daisuke Okamoto, Ryo Ichikawa, Junji Umeno, Yoichi Kakuta, Takehiro Torisu, Minoru Nakamura, Atsushi Hirano, Yasuhiro Izumiyama, Kazuhiro Watanabe, Takeru Nakano, Takeshi Naito, Motohiro Esaki, Yoshitake Kanazawa, Michiaki Unno
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Expression quantitative trait locus (eQTL) analyses have enabled us to predict the function of disease susceptibility SNPs. However, eQTL for the effector memory T cells (TEM) located in the lamina propria mononuclear cells (LPMCs), which play an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54fffec72be7b10dc92af17ca545e62d
http://link.springer.com/article/10.1038/s41598-020-66951-5
http://link.springer.com/article/10.1038/s41598-020-66951-5
Autor:
Yoichi, Kakuta, Yasuhiro, Izumiyama, Daisuke, Okamoto, Takeru, Nakano, Ryo, Ichikawa, Takeo, Naito, Rintaro, Moroi, Masatake, Kuroha, Yoshitake, Kanazawa, Tomoya, Kimura, Hisashi, Shiga, Hisaaki, Kudo, Naoko, Minegishi, Yosuke, Kawai, Katsushi, Tokunaga, Masao, Nagasaki, Yoshitaka, Kinouchi, Yasuo, Suzuki, Atsushi, Masasmune, Mai, Kato
Publikováno v:
Journal of Gastroenterology. 55:67-77
The genetic variants of NUDT15 have been verified to induce adverse events (AEs) of thiopurines. Codon 139 variants are frequently observed in Asians, while multiple variants are seen in codon 18 which also cause AEs including the European ancestry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425f4e50ee19deb6972d04cdce7e5700
https://doi.org/10.1007/s00535-019-01638-x
https://doi.org/10.1007/s00535-019-01638-x
Autor:
Yoshitaka Kinouchi, Yoichi Kakuta, Junji Umeno, Takayuki Matsumoto, Motohiro Esaki, Takeo Naito, Yuta Fuyuno, Yosuke Kawai, Takehiro Torisu, Dermot P.B. McGovern, Hisashi Shiga, Rintaro Moroi, Minoru Nakamura, Yasuhiro Izumiyama, Ryo Ichikawa, Atsushi Masamune, Daisuke Okamoto, Keiichiro Hiramoto, Masao Nagasaki, Atsushi Hirano, Masatake Kuroha, Yoshitake Kanazawa, Li Dalin, Takeru Nakano, Katsushi Tokunaga
Publikováno v:
Inflammatory bowel diseases. 26(8)
Background To clarify the genetic background of ulcerative colitis (UC) in the Japanese population, we conducted a genome-wide association study (GWAS) using a population-specific single nucleotide polymorphism (SNP) array. Methods We performed a GWA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01bf237bf577ce68bd222e64c10c390
https://pubmed.ncbi.nlm.nih.gov/32072174
https://pubmed.ncbi.nlm.nih.gov/32072174
Autor:
Yuta Fuyuno, Atsushi Hirano, Takeo Naito, Rintaro Moroi, Motoyuki Onodera, Dalin Li, Shin Matsumoto, Daisuke Okamoto, Tomoya Kimura, Junji Umeno, Hiroshi Nagai, Minoru Nakamura, Yasuhiro Izumiyama, Yosuke Kawai, Tooru Shimosegawa, Takayuki Matsumoto, Naonobu Yokoyama, Motohiro Esaki, Yusuke Shimoyama, Katsushi Tokunaga, Takeru Nakano, Masao Nagasaki, Atsushi Masamune, Dermot P.B. McGovern, Yoshitaka Kinouchi, Kenichi Negoro, Hirofumi Chiba, Masatake Kuroha, Ryo Ichikawa, Katsuya Endo, Jun Yasuda, Zhenqiu Liu, Katsutoshi Yamamoto, Yoichi Kakuta, Hisashi Shiga, Yoshitake Kanazawa
Publikováno v:
J Crohns Colitis
Background and Aims Genome-wide association studies [GWASs] of European populations have identified numerous susceptibility loci for Crohn’s disease [CD]. Susceptibility genes differ by ethnicity, however, so GWASs specific for Asian populations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e377b18de9dabe6b4571af021ad1a4cb
https://pubmed.ncbi.nlm.nih.gov/30500874
https://pubmed.ncbi.nlm.nih.gov/30500874
Autor:
Yasuhiro Izumiyama, Atsushi Masamune, Masatake Kuroha, Yoshitaka Kinouchi, Hisashi Shiga, Yoshitake Kanazawa, Tomoya Kimura, Rintaro Moroi, Ryo Ichikawa, Daisuke Okamoto, Yoichi Kakuta, Takeru Nakano
Publikováno v:
Gastroenterology. 158:S-791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c53d3e70fdff17d16b341cde534714e
https://doi.org/10.1016/s0016-5085(20)32649-4
https://doi.org/10.1016/s0016-5085(20)32649-4