Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Yasuhiro Ishihara"'
Autor:
Satsuki Ryu, Hiroki Nakashima, Yuka Tanaka, Risa Mukai, Yasuhiro Ishihara, Takashi Tominaga, Takayuki Ohshima
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 885 (2024)
Mouse double minute 2 (MDM2) is an oncoprotein that is frequently overexpressed in tumors and enhances cellular transformation. Owing to the important role of MDM2 in modulating p53 function, it is crucial to understand the mechanism underlying the r
Externí odkaz:
https://doaj.org/article/d0b39657e15243abbe5acdb86f776389
Publikováno v:
Atmospheric Environment: X, Vol 21, Iss , Pp 100237- (2024)
Spatial distributions of interleukin-8 (IL-8)-based relative inflammation potentials (IP) of PM2.5 from vehicle exhaust and non-exhaust emission sources in Japan are derived using the meteorology–chemistry model (NHM-Chem) and laboratory experiment
Externí odkaz:
https://doaj.org/article/1d991a94770c40fab743a9acf459a9ee
Autor:
Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100458- (2023)
Although pregnant women’s fish consumption is beneficial for the brain development of the fetus due to the DHA in fish, seafood also contains methylmercury (MeHg), which adversely affects fetal brain development. Epidemiological studies suggest tha
Externí odkaz:
https://doaj.org/article/e92ba8be57fa4b2ea88b871630551256
Autor:
Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F. A. Vogel, Yasuhiro Ishihara
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background A recent epidemiological study showed that air pollution is closely involved in the prognosis of ischemic stroke. We and others have reported that microglial activation in ischemic stroke plays an important role in neuronal damage
Externí odkaz:
https://doaj.org/article/0b534191fd854352af87eb926b3f7659
Autor:
Yasuhiro Ishihara, Tatsuya Honda, Nami Ishihara, Kaede Namba, Makiko Taketoshi, Yoko Tominaga, Mayumi Tsuji, Christoph F. A. Vogel, Takeshi Yamazaki, Kouichi Itoh, Takashi Tominaga
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Valproic acid (VPA) is a clinically used antiepileptic drug, but it is associated with a significant risk of a low verbal intelligence quotient (IQ) score, attention-deficit hyperactivity disorder and autism spectrum disorder in c
Externí odkaz:
https://doaj.org/article/abd2015abb394a0c8823290ebad2e5bc
Autor:
Sarah Y. Kado, Keith Bein, Alejandro R. Castaneda, Arshia A. Pouraryan, Nicole Garrity, Yasuhiro Ishihara, Andrea Rossi, Thomas Haarmann-Stemmann, Colleen A. Sweeney, Christoph F. A. Vogel
Publikováno v:
Cells, Vol 12, Iss 10, p 1433 (2023)
Indoleamine 2,3-dioxygenase 2 (IDO2) is a tryptophan-catabolizing enzyme and a homolog of IDO1 with a distinct expression pattern compared with IDO1. In dendritic cells (DCs), IDO activity and the resulting changes in tryptophan level regulate T-cell
Externí odkaz:
https://doaj.org/article/d29eb63d4d5e40e3a3c2b8a250f9ab18
Autor:
Yasuhiro Ishihara, Sarah Y. Kado, Keith J. Bein, Yi He, Arshia A. Pouraryan, Angelika Urban, Thomas Haarmann-Stemmann, Colleen Sweeney, Christoph F. A. Vogel
Publikováno v:
Frontiers in Toxicology, Vol 3 (2022)
Interleukin 22 (IL-22) is critically involved in gut immunity and host defense and primarily produced by activated T cells. In different circumstances IL-22 may contribute to pathological conditions or act as a cancer promoting cytokine secreted by i
Externí odkaz:
https://doaj.org/article/8794dec039224fd19f3e510a6798fd7f
Autor:
Mayumi Tsuji, Chihaya Koriyama, Yasuhiro Ishihara, Megumi Yamamoto, Kiwako Yamamoto-Hanada, Kumiko Kanatani, Yu Ait Bamai, Kazunari Onishi, Ayako Senju, Shunsuke Araki, Eiji Shibata, Seiichi Morokuma, Masafumi Sanefuji, Hiroshi Kitazawa, Mayako Saito, Masakazu Umezawa, Atsuto Onoda, Koichi Kusuhara, Rie Tanaka, Toshihiro Kawamoto, the Japan Environment & Children’s Study Group
Publikováno v:
Journal of Epidemiology, Vol 29, Iss 12, Pp 478-486 (2019)
Background: Metal exposures could possibly affect allergic responses in pregnant women, although no studies have yet shown a clear relationship between the two, and such exposures might also affect the development of allergic diseases in children. Me
Externí odkaz:
https://doaj.org/article/8cbcd639e0b44bba856a39631d72e55e
Autor:
Mayumi Tsuji, Eiji Shibata, David J. Askew, Seiichi Morokuma, Yukiyo Aiko, Ayako Senju, Shunsuke Araki, Masafumi Sanefuji, Yasuhiro Ishihara, Rie Tanaka, Koichi Kusuhara, Toshihiro Kawamoto, Japan Environment and Children’s Study Group
Publikováno v:
Environmental Health and Preventive Medicine, Vol 24, Iss 1, Pp 1-10 (2019)
Abstract Background Placenta previa and placenta accreta associate with high morbidity and mortality for both mothers and fetus. Metal exposure may have relationships with placenta previa and placenta accreta. This study analyzed the associations bet
Externí odkaz:
https://doaj.org/article/23564b47ec354616b74145cf2643cc6b
Publikováno v:
European Journal of Medical Research, Vol 23, Iss 1, Pp 1-9 (2018)
Abstract Background Recent studies have reported that endocrine-disrupting compound (EDC) exposure is related to food sensitization. Bisphenol A diglycidyl ether (BADGE) is one of the most widespread EDCs and its biological effects are considered to
Externí odkaz:
https://doaj.org/article/8dd02a0384f14f02883c08e2fd7d8e60