Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Yasuhiko Okimura"'
Autor:
Hikaru Nishida, Ayaka Ikegami, Chiaki Kaneko, Hitomi Kakuma, Hisano Nishi, Noriko Tanaka, Michiko Aoyama, Makoto Usami, Yasuhiko Okimura
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128805 (2015)
Branched-chain amino acids (BCAAs) and IGF-I, the secretion of which is stimulated by growth hormone (GH), prevent muscle atrophy. mTOR plays a pivotal role in the protective actions of BCAA and IGF-1. The pathway by which BCAA activates mTOR is diff
Externí odkaz:
https://doaj.org/article/e9e48f37651e439baab46481d177ac34
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54437 (2013)
Previous studies have shown that the locus control region (LCR) and the promoter of the growth hormone (GH) gene can control the expression of GH. Therefore, lenti- and retro-viral vectors with these elements might be useful to monitor the activation
Externí odkaz:
https://doaj.org/article/4383e79f7c2f4236b4afa356caf64c3b
Autor:
Hitoshi Ishii, Akira Shimatsu, Yasuhiko Okimura, Toshiaki Tanaka, Naomi Hizuka, Hidesuke Kaji, Kunihiko Hanew, Yutaka Oki, Sayuri Yamashiro, Koji Takano, Kazuo Chihara
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44304 (2012)
OBJECTIVE: To develop and validate the Adult Hypopituitarism Questionnaire (AHQ) as a disease-specific, self-administered questionnaire for evaluation of quality of life (QOL) in adult patients with hypopituitarism. METHODS: We developed and validate
Externí odkaz:
https://doaj.org/article/8ecb6778c360402996305a050e70d408
Autor:
Yasuhiko Okimura, Yusuke Kato, Hiroyasu Makino, Kunihiro Hashimoto, Yasuhiro Maeda, Toshimitsu Okane, Muhammad Khairi Faiz, Hideo Komine, Tomoyuki Miyashita, Makoto Yoshida
Publikováno v:
Journal of Materials Processing Technology. 318:118020
Autor:
Yasuhiko Okimura, Yusuke Kato, Hiroyasu Makino, Kunihiro Hashimoto, Yasuhiro Maeda, Toshimitsu Okane, Muhammad Khairi Faiz, Hideo KOMINE, Tomoyuki Miyashita, Makoto Yoshida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d61dedd0c6d3486d109bfa827f0c2140
https://doi.org/10.2139/ssrn.4402097
https://doi.org/10.2139/ssrn.4402097
Autor:
Hitoshi Nishizawa, Kentaro Suda, Keiko Muguruma, Wataru Ogawa, Keitaro Kanie, Yasuhiko Okimura, Ryusaku Matsumoto, Genzo Iguchi, Ryoko Hidaka-Takeno, Hidenori Fukuoka, Hironori Bando, Yasunori Fujita, Masaaki Yamamoto, Ken-ichi Yoshida, Yutaka Takahashi
Publikováno v:
Journal of the Endocrine Society
Context Anti–pituitary-specific transcriptional factor-1 (anti–PIT-1) antibody syndrome is characterized by acquired and specific deficiencies in growth hormone, prolactin, and thyroid-stimulating hormone. Although PIT-1–reactive cytotoxic T ly
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130174
Sestrin2 is a conserved protein in several species, and its expression is upregulated in cells under various environmental stresses. Sestrin2 content is involved in the function of mechanistic target of rapamycin complex 1 (mTORC1) in mouse embryonic
Publikováno v:
Nutrition Research. 47:13-20
Branched chain amino acids (BCAAs) have protective effects against muscle atrophy. Although plasma BCAA concentrations are higher in patients with diabetes than in healthy subjects, diabetes is related to sarcopenia. We hypothesized that high glucose
Publikováno v:
Growth Hormone & IGF Research. 59:101406
Objective IGF-I and branched-chain amino acids have been reported to promote muscle hypertrophy via the stimulation of protein synthesis. Sestrin2, the function of which is regulated by leucine, has been reported to attenuate the activity of the mech
Autor:
Yasuhiko Okimura, Ryusaku Matsumoto, Genzo Iguchi, Michiko Takahashi, Hironori Bando, Ryoko Hidaka-Takeno, Yutaka Takahashi, Hidenori Fukuoka, Masaaki Yamamoto, Katsuyoshi Tojo, Hitoshi Nishizawa, Kentaro Suda
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E1744-E1749
Context: Anti-pituitary-specific transcriptional factor 1 (PIT-1) antibody syndrome is characterized by acquired growth hormone (GH), prolactin (PRL), and thyroid-stimulating hormone (TSH) deficiencies associated with circulating anti-PIT-1 antibodie