Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yasuhiko Ikari"'
Autor:
Go Akamatsu, Yasuhiko Ikari, Akihito Ohnishi, Keiichi Matsumoto, Hiroyuki Nishida, Yasuji Yamamoto, Michio Senda, Japanese Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Background Amyloid PET plays a vital role in detecting the accumulation of in vivo amyloid-β (Aβ). The quantification of Aβ accumulation has been widely performed using the region of interest (ROI)-based mean cortical standardized uptake
Externí odkaz:
https://doaj.org/article/1b529a8a0d11410c81ce5cd405b61044
Autor:
Akihito Ohnishi, Go Akamatsu, Yasuhiko Ikari, Hiroyuki Nishida, Keiji Shimizu, Keiichi Matsumoto, Kazuki Aita, Masahiro Sasaki, Yasuji Yamamoto, Tomohiko Yamane, Michio Senda
Publikováno v:
Annals of Nuclear Medicine. 37:108-120
Objective A new tau PET tracer [18F]MK-6240 has been developed; however, its dosimetry and pharmacokinetics have been published only for a European population. This study investigated the safety, radiation dosimetry, pharmacokinetics and biodistribut
Autor:
Go, Akamatsu, Yasuhiko, Ikari
Publikováno v:
Japanese Journal of Radiological Technology. 78:383-388
Autor:
Kazuya Maeda, Yasuhiko Ikari, Akihito Ohnishi, Michio Senda, Yuichi Sugiyama, Masahiro Sasaki, Yasuyoshi Watanabe, Kazuki Aita, Hiroyuki Kusuhara
Publikováno v:
Drug Metabolism and Pharmacokinetics. 34:293-299
The pharmacokinetics of telmisartan are nonlinear within the clinical dose range. To identify the underlying mechanism of this nonlinearity, we conducted a PET study in healthy subjects using [11C]telmisartan. Eight healthy male subjects were enrolle
Publikováno v:
Radiological Physics and Technology. 10:464-474
Dynamic 11C-PiB PET imaging with kinetic analysis has been performed for accurate quantification of amyloid binding in patients with Alzheimer's disease (AD). In this study, we measured the whole-body biodistribution of 11C-PiB in nine subjects. We t
Publikováno v:
Japanese Journal of Radiological Technology. 73:298-308
Brain imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), and positron emission tomography (PET), can provide essential and objective information for the early an
Autor:
Yasuhiko Ikari, Hiroyuki Nishida, Japanese Alzheimer's Disease Neuroimaging Initiative, Michio Senda, Keiichi Matsumoto, Akihito Ohnishi, Yasuji Yamamoto, Go Akamatsu
Publikováno v:
EJNMMI Research
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
BackgroundAmyloid PET plays a vital role in detecting the accumulation of in vivo amyloid-β (Aβ). The quantification of Aβ accumulation has been widely performed using the region of interest (ROI)-based mean cortical standardized uptake value rati
Autor:
Michio Senda, Kengo Ito, Kenji Ishii, Tomohiko Yamane, Kazunari Ishii, Yasuhiko Ikari, Muneyuki Sakata, Takashi Kato, Tomoyuki Nishio
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 44:850-857
The aim of this study was to assess the inter-rater variability of the visual interpretation of 11C-PiB PET images regarding the positivity/negativity of amyloid deposition that were obtained in a multicenter clinical research project, Japanese Alzhe
Autor:
Michio Senda, Akihito Ohnishi, Yasuhiko Ikari, Go Akamatsu, Kazuki Aita, Nobuo Kohara, Masahiro Sasaki, Hiroyuki Nishida
Publikováno v:
Annals of Nuclear Medicine. 31:163-171
With the advent of regenerative/cell therapy for Parkinson’s disease (PD), 18F-FDOPA has drawn new attention as a biomarker of the therapeutic that cannot be evaluated with radiopharmaceuticals for dopamine transporter. Since most previous 18F-FDOP
Autor:
Yasuhiko Ikari, Akihito Ohnishi, Yasuji Yamamoto, Hiroyuki Nishida, Kazuki Aita, Masahiro Sasaki, Michio Senda, Kenichi Matsuyama, Go Akamatsu, Kazuo Sakai
Publikováno v:
Alzheimer's & Dementia. 15:P1092-P1093