Zobrazeno 1 - 10
of 452
pro vyhledávání: '"Yasuhide, Hayashi"'
Autor:
Yu Tao, Li Wei, Norio Shiba, Daisuke Tomizawa, Yasuhide Hayashi, Seishi Ogawa, Li Chen, Hua You
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-16 (2024)
Abstract Risk classification in pediatric acute myeloid leukemia (P-AML) is crucial for personalizing treatments. Thus, we aimed to establish a risk-stratification tool for P-AML patients and eventually guide individual treatment. A total of 256 P-AM
Externí odkaz:
https://doaj.org/article/47a7f43a6fba48b5b2cf9f7023bf3b46
Autor:
Hidemasa Matsuo, Kenichi Yoshida, Yasuhito Nannya, Yuri Ito, Aina Inagami, Nana Ito, Shinju Iyoda, Shoji Saito, Yuhki Koga, Hiroshi Moritake, Kiminori Terui, Koji Kawaguchi, Yasuhiro Okamoto, Hideki Nakayama, Miyako Kanno, Moeko Hino, Yusuke Akane, Akiko Inoue, Akira Shimada, Hiroaki Goto, Hiroo Ueno, Junko Takita, Genki Yamato, Norio Shiba, Yasuhide Hayashi, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Akio Tawa, Seishi Ogawa, Souichi Adachi
Publikováno v:
HemaSphere, Vol 7, p e51775a7 (2023)
Externí odkaz:
https://doaj.org/article/b478cedad9be4228b9525726b04942b5
Autor:
Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3157-3169 (2019)
Abstract: Recent advances in the genetic understanding of acute myeloid leukemia (AML) have improved clinical outcomes in pediatric patients. However, ∼40% of patients with pediatric AML relapse, resulting in a relatively low overall survival rate
Externí odkaz:
https://doaj.org/article/2ec3e3d04c7b43d39e264c81ce939535
Autor:
Yusuke Hara, Norio Shiba, Kenichi Yoshida, Genki Yamato, Taeko Kaburagi, Yuichi Shiraishi, Kentaro Ohki, Yusuke Shiozawa, Machiko Kawamura, Hirohide Kawasaki, Manabu Sotomatsu, Takumi Takizawa, Hidemasa Matsuo, Akira Shimada, Nobutaka Kiyokawa, Daisuke Tomizawa, Takashi Taga, Etsuro Ito, Keizo Horibe, Satoru Miyano, Souichi Adachi, Tomohiko Taki, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Genes, Chromosomes and Cancer. 62:412-422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6b2702e81d216c3c0345f42d741c555
https://doi.org/10.1002/gcc.23147
https://doi.org/10.1002/gcc.23147
Autor:
Taeko Kaburagi, Genki Yamato, Norio Shiba, Kenichi Yoshida, Yusuke Hara, Ken Tabuchi, Yuichi Shiraishi, Kentaro Ohki, Manabu Sotomatsu, Hirokazu Arakawa, Hidemasa Matsuo, Akira Shimada, Tomohiko Taki, Nobutaka Kiyokawa, Daisuke Tomizawa, Keizo Horibe, Satoru Miyano, Takashi Taga, Souichi Adachi, Seishi Ogawa, Yasuhide Hayashi
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
RAS pathway alterations have been implicated in the pathogenesis of various hematological malignancies. However, their clinical relevance in pediatric acute myeloid leukemia (AML) is not well characterized. We analyzed the frequency, clinical signifi
Externí odkaz:
https://doaj.org/article/fdbcc55b426043c281c3397ca42dc1a5
Autor:
Shunsuke Kimura, Masahiro Sekiguchi, Kentaro Watanabe, Mitsuteru Hiwatarai, Masafumi Seki, Kenichi Yoshida, Tomoya Isobe, Yusuke Shiozawa, Hiromichi Suzuki, Noriko Hoshino, Yasuhide Hayashi, Akira Oka, Satoru Miyano, Seishi Ogawa, Junko Takita
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245526 (2021)
Neuroblastoma, the most common extracranial solid malignancy among children, originates from undifferentiated neural crest cells (NCC). Despite recent intensified treatment, high-risk patients still have a high mortality rate. To explore a new therap
Externí odkaz:
https://doaj.org/article/cb5d0acf895940d789cb063b2d233882
Autor:
Kentaro Ohki, Nobutaka Kiyokawa, Yuya Saito, Shinsuke Hirabayashi, Kazuhiko Nakabayashi, Hitoshi Ichikawa, Yukihide Momozawa, Kohji Okamura, Ai Yoshimi, Hiroko Ogata-Kawata, Hiromi Sakamoto, Motohiro Kato, Keitaro Fukushima, Daisuke Hasegawa, Hiroko Fukushima, Masako Imai, Ryosuke Kajiwara, Takashi Koike, Isao Komori, Atsushi Matsui, Makiko Mori, Koichi Moriwaki, Yasushi Noguchi, Myoung-ja Park, Takahiro Ueda, Shohei Yamamoto, Koichi Matsuda, Teruhiko Yoshida, Kenji Matsumoto, Kenichiro Hata, Michiaki Kubo, Yoichi Matsubara, Hiroyuki Takahashi, Takashi Fukushima, Yasuhide Hayashi, Katsuyoshi Koh, Atsushi Manabe, Akira Ohara, for the Tokyo Children’s Cancer Study Group (TCCSG)
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Fusion genes involving MEF2D have recently been identified in precursor B-cell acute lymphoblastic leukemia, mutually exclusive of the common risk stratifying genetic abnormalities, although their true incidence and associated clinical characteristic
Externí odkaz:
https://doaj.org/article/39bd7c93956e4a3d96be17dfe62c22b9
Autor:
Genki Yamato, Tomoko Kawai, Norio Shiba, Junji Ikeda, Yusuke Hara, Kentaro Ohki, Shin-Ichi Tsujimoto, Taeko Kaburagi, Kenichi Yoshida, Yuichi Shiraishi, Satoru Miyano, Nobutaka Kiyokawa, Daisuke Tomizawa, Akira Shimada, Manabu Sotomatsu, Hirokazu Arakawa, Souichi Adachi, Takashi Taga, Keizo Horibe, Seishi Ogawa, Kenichiro Hata, Yasuhide Hayashi
Publikováno v:
Blood Advances. 6:3207-3219
We investigated genome-wide DNA methylation patterns in 64 pediatric patients with acute myeloid leukemia (AML). Based on unsupervised clustering with the 567 most variably methylated cytosine guanine dinucleotide (CpG) sites, patients were categoriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb2be8cda868149fe6254a08c5508bc
https://doi.org/10.1182/bloodadvances.2021005381
https://doi.org/10.1182/bloodadvances.2021005381
Autor:
Junko Takita, Seishi Ogawa, Yasuhide Hayashi, Satoru Miyano, Takashi Igarashi, Akira Oka, Toshiaki Ishida, Myoung-Ja Park, Yuko Nomura, Ryoji Hanada, Motohiro Kato, Keisuke Kato, Hiroko Tanaka, Kenichi Chiba, Yusuke Okuno, Riki Nishimura, Yusuke Sato, Teppei Shimamura, Yuichi Shiraishi, Kenichi Yoshida, Masafumi Seki
Pleuropulmonary blastoma (PPB) is a rare pediatric malignancy whose pathogens are poorly understood. Recent reports suggest that germline mutations in the microRNA-processing enzyme DICER1 may contribute to PPB development. To investigate the genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63514723439991d2ff5695803f61cde9
https://doi.org/10.1158/0008-5472.c.6505487
https://doi.org/10.1158/0008-5472.c.6505487
Autor:
Junko Takita, Seishi Ogawa, Yasuhide Hayashi, Satoru Miyano, Takashi Igarashi, Akira Oka, Toshiaki Ishida, Myoung-Ja Park, Yuko Nomura, Ryoji Hanada, Motohiro Kato, Keisuke Kato, Hiroko Tanaka, Kenichi Chiba, Yusuke Okuno, Riki Nishimura, Yusuke Sato, Teppei Shimamura, Yuichi Shiraishi, Kenichi Yoshida, Masafumi Seki
PDF file - 1805KB, Supplementary Table S1. List of primers used for validation of somatic mutations detected by whole-exome sequencing. Supplementary Table S2. Primers for DICER1 sequencing of all coding exons. Supplementary Table S3. Primers for DIC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc4db6533d83a3cb25755c37495c5ef
https://doi.org/10.1158/0008-5472.22400054
https://doi.org/10.1158/0008-5472.22400054