Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yasuharu Ishihara"'
Autor:
Kazunari Onodera, Daisuke Shimojo, Yasuharu Ishihara, Masato Yano, Fuyuki Miya, Haruhiko Banno, Naoko Kuzumaki, Takuji Ito, Rina Okada, Bruno de Araújo Herculano, Manabu Ohyama, Mari Yoshida, Tatsuhiko Tsunoda, Masahisa Katsuno, Manabu Doyu, Gen Sobue, Hideyuki Okano, Yohei Okada
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Spinal bulbar muscular atrophy (SBMA) is an adult-onset, slowly progressive motor neuron disease caused by abnormal CAG repeat expansion in the androgen receptor (AR) gene. Although ligand (testosterone)-dependent mutant AR aggregation has b
Externí odkaz:
https://doaj.org/article/c9f6034e190445819b495df34c6fae53
Autor:
Kenji Kubara, Kazuto Yamazaki, Yasuharu Ishihara, Takuya Naruto, Huan-Ting Lin, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Masashi Ito, Kappei Tsukahara, Tomohiro Morio, Masatoshi Takagi, Makoto Otsu
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 380-394 (2018)
Summary: Oncogenic KRAS mutations in hematopoietic stem cells cause RAS-associated autoimmune lymphoproliferative syndrome-like disease (RALD). KRAS plays essential roles in stemness maintenance in some types of stem cells. However, its roles in plur
Externí odkaz:
https://doaj.org/article/bec0e0806fec42e48f4d3ad662e1e2de
Autor:
Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 6, Iss 4, Pp 496-510 (2016)
Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disorder. Although its neuropathology is well understood, the cellular and molecular mechanisms are yet to be elucidated due to limitations in the currently available human genetic data
Externí odkaz:
https://doaj.org/article/5db54311c6d3457289259a0447a5884a
Autor:
Haruhiko Banno, Takuji Ito, Tatsuhiko Tsunoda, Yohei Okada, Yasuharu Ishihara, Hideyuki Okano, Mari Yoshida, Daisuke Shimojo, Masahisa Katsuno, Masato Yano, Manabu Ohyama, Fuyuki Miya, Kazunari Onodera, Bruno Herculano, Naoko Kuzumaki, Rina Okada, Gen Sobue, Manabu Doyu
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Molecular Brain
Molecular Brain
Spinal bulbar muscular atrophy (SBMA) is an adult-onset, slowly progressive motor neuron disease caused by abnormal CAG repeat expansion in the androgen receptor (AR) gene. Although ligand (testosterone)-dependent mutant AR aggregation has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016976c18b3f1058978c296cb499874d
https://doi.org/10.21203/rs.2.20096/v2
https://doi.org/10.21203/rs.2.20096/v2
Autor:
Yasuharu Ishihara, Mahito Nakanishi, Huan-Ting Lin, Makoto Otsu, Takuya Naruto, Masashi Ito, Kappei Tsukahara, Kenji Kubara, Kazuto Yamazaki, Tomohiro Morio, Ken Nishimura, Manami Ohtaka, Masatoshi Takagi
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 380-394 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Oncogenic KRAS mutations in hematopoietic stem cells cause RAS-associated autoimmune lymphoproliferative syndrome-like disease (RALD). KRAS plays essential roles in stemness maintenance in some types of stem cells. However, its roles in pluri
Autor:
Yasuharu Ishihara, Michiko Sugawara, Kazuto Yamazaki, Yoichi Imaizumi, Kazuyuki Fukushima, Yoshikuni Tabata, Masashi Ito, Jun Kohyama, Kappei Tsukahara, Hideyuki Okano
Publikováno v:
SLAS Discovery. 21:1054-1064
Because neurons are difficult to obtain from humans, generating functional neurons from human induced pluripotent stem cells (hiPSCs) is important for establishing physiological or disease-relevant screening systems for drug discovery. To examine the
Autor:
Naoto Watanabe, Ayano Kimura, Yasuharu Ishihara, Tatsuto Fukushima, Kunihiko Kanatsu, Yasuaki Goto, Makoto Nakagawa, Masafumi Tsuboi
Publikováno v:
Alzheimer's & Dementia. 15:P595-P595
Autor:
Masashi Hosokawa, Yasuharu Ishihara, Keikichi Sugiyama, Tomoji Ono, Michiaki Murakoshi, Satoru Morishita, Chikako Fujisaki, Hisanori Kato, Kazuo Miyashita, Hoyoku Nishino
Publikováno v:
Journal of Oleo Science. 62:97-103
Lactoferrin (LF) is a multi-functional glycoprotein found in milk. In a previous clinical trial, we showed that enteric-coated bovine LF (bLF) tablets could reduce visceral fat accumulation. We also showed that bLF had anti-adipogenic activity in vit
Autor:
Manabu Doyu, Chinatsu Hattori, Masanobu Shoji, Yasuharu Ishihara, Hideyuki Okano, Rina Okada, Daisuke Shimojo, Satoshi Tanaka, Atsushi Nakanishi, Kazunari Onodera, Yukiko Doi-Torii, Manabu Ohyama, Yohei Okada, Yukino Miwa
Publikováno v:
Molecular Brain
Background Human pluripotent stem cells (hPSCs) are being applied in regenerative medicine and for the in vitro modeling of human intractable disorders. In particular, neural cells derived from disease-specific human induced pluripotent stem cells (h
Autor:
Gen Sobue, D. Simojo, Kazunari Onodera, Masahisa Katsuno, Yohei Okada, Manabu Doyu, Yasuharu Ishihara, Hideyuki Okano
Publikováno v:
Journal of the Neurological Sciences. 381:708