Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yasuharu, Akasaki"'
Autor:
Jun Takei, Nei Fukasawa, Toshihide Tanaka, Yohei Yamamoto, Ryota Tamura, Hikaru Sasaki, Yasuharu Akasaki, Yuko Kamata, Mutsunori Murahashi, Masayuki Shimoda, Yuichi Murayama
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPreviously, we reported that bevacizumab (Bev) produces histological and neuroradiographic alterations including changes in tumor oxygenation, induction of an immunosupportive tumor microenvironment, and inhibition of stemness. To confirm h
Externí odkaz:
https://doaj.org/article/64946f3b3bd34947a7f623ddef39de95
Autor:
Nobuyuki Watanabe, Kentaro Watanabe, Soichiro Fujimura, Kostadin L. Karagiozov, Ryosuke Mori, Takuya Ishii, Yuichi Murayama, Yasuharu Akasaki
Publikováno v:
Operative Neurosurgery. 24:548-555
Autor:
Mana Inada, Mika Shindo, Kyousuke Kobayashi, Akira Sato, Yohei Yamamoto, Yasuharu Akasaki, Koichi Ichimura, Sei-Ichi Tanuma
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216358 (2019)
The interaction between high-mobility group box 1 protein (HMGB1) and receptor for advanced glycation end products (RAGE) is important for tumor cell growth. We investigated the tumor biological effects of HMGB1 and RAGE interaction. Previously, we i
Externí odkaz:
https://doaj.org/article/5429890d3e174df3b26f77a833ffc7a6
Autor:
Tomoya Suzuki, Jun Takei, Nei Fukasawa, Kenta Suzuki, Daisuke Ogawa, Yohei Yamamoto, Yasuharu Akasaki, Yuichi Murayama, Masayuki Shimoda, Keisuke Miyake, Toshihide Tanaka
Publikováno v:
World Neurosurgery.
Background Gadolinium-enhanced magnetic resonance imaging and T2-weighted imaging/fluid-attenuated inversion recovery imaging are used to determine the efficacy of bevacizumab (Bev) against glioblastoma (GBM). Positron emission tomography (PET) using
Autor:
Yohei Yamamoto, Syohei Nawate, Aya Nakamura, Takuya Ishii, Toshihide Tanaka, Yasuharu Akasaki, Yuichi Murayama
Publikováno v:
Neuro-Oncology Advances. 4:iii21-iii22
Introduction Among metastatic brain tumors, especially in cases where the primary tumor and metastatic brain tumor are found at the same time, it is necessary to consider the priority of treatment for intracranial lesions and the means to obtain a de
Autor:
Taketo Ezaki, Ryota Tamura, Toshihide Tanaka, Keisuke Miyake, Yuki Kuranari, Yohei Yamamoto, Jun Takei, Yasuharu Akasaki, Masahiro Toda, Yuichi Murayama, Takashi Tamiya, Hikaru Sasaki
Publikováno v:
Neuro-Oncology Advances. 4:iii14-iii15
To date, few clinical observations have been reported for changes of alternative angiogenic factors (other than vascular endothelial growth factor [VEGF]) in human gliomas under bevacizumab (Bev). The elucidation of the mechanism of action and resist
Autor:
Ryosuke, Mori, Yasuharu, Akasaki, Nei, Fukasawa, Daichi, Kawamura, Kostadin, Karagiozov, Yuichi, Murayama
Publikováno v:
Turkish Neurosurgery.
To improve the extent and safety of resecting these deep-seated tumors, we report a novel procedure of minimally invasive endoscopic resection of deep-seated pilocytic astrocytomas under the guidance of 5-aminolevulinic acid (5-ALA) fluorescence unde
Publikováno v:
Neuro-Oncology Advances. 4:iii27-iii27
We started a research of dendritic cell (DC) immunotherapy for malignant glioma in late 1997, and were continuing the clinical study for more than 20 years with making several improvements of methods. The presenter has been participating in this rese
Autor:
Kyoichi Tomoto, Yohei Yamamoto, Toshihide Tanaka, Tomoya Suzuki, Akihiko Teshigawara, Jun Takei, Hirokazu Koseki, Ryosuke Mori, Yasuharu Akasaki, Yuichi Murayama
Publikováno v:
Neuro-Oncology Advances. 4:iii8-iii8
Background Since phase 3 randomized clinical trials failed to show the benefit of bevacizumab(Bev) from the induction therapy, Bev was widely used for the recurrence glioblastoma(GBM) cases. Given that Bev treatment for newly diagnosed GBM(nd-GBM) is
Autor:
Yasuharu Akasaki, Tomoya Suzuki, Jun Takei, Toshihide Tanak, Ryosuke Mori, Hirokazu Koseki, Yohei Yamamoto, Akihiko Teshigawara, Yuko Kamata, Takaaki Yanagisawa, Yuichi Murayama
Publikováno v:
Neuro-Oncology Advances. 4:iii12-iii12
Since a diffuse midline glioma (DMG) has no effective therapy, it is an urgent need to develop new therapeutic strategy. We performed immunotherapy using fusions of autologous dendritic cells (DC) with tumor cells in DMG cases in which tumor tissue w