Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yasufumi Oshima"'
Publikováno v:
Journal of Controlled Release. 323:323-332
Biological macromolecular drugs, such as antibodies and fusion protein drugs, have been widely employed for the treatment of various diseases. Administration routes are typically via invasive intravenous or subcutaneous injection with needles; the la
Autor:
Naoshi Yamazaki, Tamotsu Tanaka, Tatsuya Fukuta, Hidenori Ando, Tasuku Torao, Miyuki Mimura, Yasufumi Oshima, Koki Fujikawa, Tatsuharu Shimokawa, Tatsuhiro Ishida, Mahadi Hasan, Kentaro Kogure
Publikováno v:
International Journal of Pharmaceutics. 576:119010
We previously reported that 20 a weak current (WC, 0.3-0.5mA/cm2) applied to cells can induce endocytosis to promote cytoplasmic delivery of hydrophilic macromolecules (MW: < 70,000), such as dextran and siRNA, which leak from WC-induced endosomes in
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 8:321-323
Giant-axonal neuropathy (GAN), a chronic peripheral neuropathy with associated Central Nervous System dysfunction and tight curly hair, is described in a 17-year-old girl. Biopsies of this girl’s muscle and nerve are characteristic of this conditio