Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yasufumi Ohkura"'
Autor:
Kazuhiro Ikegai, Takeshi Murakami, Yasufumi Ohkura, Yoshinori Kobayashi, Makoto Takeuchi, Ryota Shiraki, Takashi Ogiyama, Hiroshi Tomiyama, Atsushi Noda, Masakazu Imamura, Masayuki Yokota, Eiji Kurosaki, Kazuhiro Kosakai, Keita Nakanishi, Tomokazu Koide, Mitsuaki Ohta, Takayuki Suzuki
Publikováno v:
Bioorganicmedicinal chemistry. 20(10)
A series of C-glucosides with various heteroaromatics has been synthesized and its inhibitory activity toward SGLTs was evaluated. Upon screening several compounds, the benzothiophene derivative (14a) was found to have potent inhibitory activity agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427aab19d695a71f7869680d9ace5a71
https://pubmed.ncbi.nlm.nih.gov/22507206
https://pubmed.ncbi.nlm.nih.gov/22507206
Autor:
Hideyo Takahashi, Yasufumi Ohkura, Hidetoshi Miyamoto, Rie Namme, Shiro Ikegami, Toshimitsu Fukuda, Haruhiko Mitsuzuka
Publikováno v:
Angewandte Chemie (International ed. in English). 42(41)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05105647b3b60bc224e44c4130f981fd
https://pubmed.ncbi.nlm.nih.gov/14595635
https://pubmed.ncbi.nlm.nih.gov/14595635
Autor:
Tomoe Sato, Chika Fukai, Kazuya Furuta, Kenji Hase, Shuichi Wakabayashi, Yasufumi Ohkura, Akira Tomiyama, Kazuhiro Kosakai, Seiichiro Mochizuki
Publikováno v:
Journal of cardiovascular pharmacology. 25(1)
We examined pharmacological profiles of KT3-671, 2-propyl-8-oxo-1-[(2'-(1H-tetrazole-5-yl) biphenyl-4-yl)methyl]- 4,5,6,7-tetrahydro-cycloheptimidazole, a newly synthesized nonpeptide angiotensin II (AII) receptor antagonist in various in vitro and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17f838ccd48f2e9856b72089bc305c5
https://pubmed.ncbi.nlm.nih.gov/7723348
https://pubmed.ncbi.nlm.nih.gov/7723348
Publikováno v:
Microbial Infections ISBN: 9781461365198
The traditional Chinese medicine Sho-saiko-to (Xiao-Chai-Hu-Tang) is prepared from the herbs Bupleuri radix, Pinelliae tuber, Scutellariae radix, Zizyphifractus, Ginseng radix, Glycyrrhizae radix and Zingiberis rhizoma, and has been used for the trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d16d81a998ae6ef60a553f5d207ba2a9
https://doi.org/10.1007/978-1-4615-3434-1_31
https://doi.org/10.1007/978-1-4615-3434-1_31
Autor:
Masaki Aburada, Seiji Morisawaz, Shoji Kubo, Yasufumi Ohkura, Hiroaki Kinoshita, Yasuhiro Mizoguchi, Shigefumi Takeda, Isao Yuasa, Shuzo Otani
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 25:1190-1190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f4c89c07d09c0386d0687e231f9180c
https://doi.org/10.5833/jjgs.25.1190
https://doi.org/10.5833/jjgs.25.1190
Autor:
Masaki Aburada, Seiji Morisawa, Shigefumi Takeda, Yoshihide Sakagami, Sukeo Yamamoto, Yasufumi Ohkura, Kenzo Kobayashi, Yasuhiro Mizoguchi
Publikováno v:
Japanese Journal of Pharmacology. 44:179-185
TJN-101, which is a lignan component isolated from schisandra fruits, inhibits hepatotoxic chemicals-induced liver injuries. In this study, effects of TJN-101 on immunologically induced liver injuries were investigated in vivo and in vitro. When a sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a125a1276870428169f5c249c67a5f7
https://doi.org/10.1254/jjp.44.179
https://doi.org/10.1254/jjp.44.179
Autor:
Shigefumi TAKEDA, Shyuji FUNO, Akira IIZUKA, Yoshio KASE, Ichiro ARAI, Yasufumi OHKURA, Kazuhiko SUDO, Noriko KIUCHI, Chizuru YOSHIDA, Shinya MAEDA, Masaki ABURADA, Eikichi HOSOYA
Publikováno v:
Folia Pharmacologica Japonica. 85:193-208
The effects of wuweizisu C, a lignan component of schizandra fruits, on liver injuries induced by carbon tetrachloride (CCl4), d-galactosamine and dl-ethionine were investigated by means of serum-biochemical and histopathological examinations in rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff671e753ce43e2ffd78b6487f0a6977
https://doi.org/10.1254/fpj.85.193
https://doi.org/10.1254/fpj.85.193
Publikováno v:
Folia Pharmacologica Japonica. 82:19-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d165cc9dfae963c106255cbb1a9e0921
https://doi.org/10.1254/fpj.82.19
https://doi.org/10.1254/fpj.82.19
Autor:
Yoshio Kase, Eikichi Hosoya, Akemi Tatsugi, Masayuki Hasegawa, Yuko Sekiguchi, Yasufumi Ohkura, Ichiro Arai, Shuji Funo, Shigefumi Takeda, Masaki Aburada
Publikováno v:
Folia Pharmacologica Japonica. 90:51-65
TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy -6,7-dimethyl-10,11-methylenedioxy-6-dibenzo[a,c]cyclooctenol) is one of the lignan compounds isolated from Schisandra fruits. 1) Effect of TJN-101 on liver fibrosis was investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f5649a21e247e99e8137dd9705d7ae
https://doi.org/10.1254/fpj.90.51
https://doi.org/10.1254/fpj.90.51
Autor:
Eikichi Hosoya, Shigefumi Takeda, Ichiro Arai, Yuko Sekiguchi, Masayuki Hasegawa, Kazuhiko Sudo, Yasufumi Ohkura, Yoshio Kase, Masaki Aburada
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 107(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d429bc974ced3ee80157ac34541c24fb
https://pubmed.ncbi.nlm.nih.gov/3694461
https://pubmed.ncbi.nlm.nih.gov/3694461