Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yasufumi Fukano"'
Publikováno v:
Molecular and cellular endocrinology. 494
Natriuretic peptides regulate cyclic guanosine monophosphate (cGMP) levels via their receptors and have various physiological effects. Natriuretic peptide receptor C (NPR-C) increases cGMP signaling by functioning as a clearance receptor. We analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be256c65577d90746fd12c9f70b0626a
https://pubmed.ncbi.nlm.nih.gov/31255729
https://pubmed.ncbi.nlm.nih.gov/31255729
Publikováno v:
Biochemical and Biophysical Research Communications. 478:624-630
We report the usefulness of an impedance-based label-free whole cell assay to identify new ligands for G protein-coupled receptors (GPCRs) involved in microglial cell migration. Authentic GPCR ligands were subjected to the impedance-based cell assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a449c32ceb3879660fbb77885a1afb66
https://doi.org/10.1016/j.bbrc.2016.07.119
https://doi.org/10.1016/j.bbrc.2016.07.119
Autor:
Shiro Amano, Naoto Mori, Masatsugu Nakamura, Reiko Arita, Kouichi Kawazu, Yasufumi Fukano, Rika Shirakawa
Publikováno v:
Journal of Chromatography A. 1347:129-136
We report a rapid liquid chromatography/quadrupole Orbitrap Fourier transform mass spectrometry (LC–FTMS) method for identifying free fatty acids (FAs) and (O-acyl)-ω-hydroxyFAs (OAHFAs) in human meibum without derivatization. Meibum is a lipid-ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d75f281b23c34a9c3e7c94f9780bc8
https://doi.org/10.1016/j.chroma.2014.04.082
https://doi.org/10.1016/j.chroma.2014.04.082
Autor:
Reiko Arita, Naoto Mori, Takahiro Imanaka, Kei Asai, Masatsugu Nakamura, Rika Shirakawa, Yasufumi Fukano
Publikováno v:
Experimental eye research. 145
To examine the relation between changes in the free fatty acid (FFA) composition of human meibum and both objective signs and subjective symptoms of meibomian gland dysfunction (MGD), we analyzed the FFA content of meibum collected from both MGD pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99e799665ae8b48336633893579fe20
https://pubmed.ncbi.nlm.nih.gov/26919787
https://pubmed.ncbi.nlm.nih.gov/26919787
Autor:
Kei Asai, Shiro Amano, Takahiro Imanaka, Yasufumi Fukano, Naoto Mori, Reiko Arita, Rika Shirakawa, Masatsugu Nakamura
Publikováno v:
Investigative ophthalmologyvisual science. 56(8)
Purpose We measured the components of meibum in patients with meibomian gland dysfunction (MGD) and control subjects and then examined the relation between meibum composition and clinical parameters. Methods Thirty-eight patients with MGD (13 men and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90be826b297f6706344ea34178a128b0
https://pubmed.ncbi.nlm.nih.gov/26176877
https://pubmed.ncbi.nlm.nih.gov/26176877
Autor:
Tsuyoshi Azuma, Hiroko Hayashi, Jun-ich Miyazaki, Atsushi Tamura, Tsutomu Masujima, Yasuyo Masumoto, Yasufumi Fukano, Koichiro Ozawa
Publikováno v:
Analytica Chimica Acta. 365:3-7
Secretion of insulin from pancreatic the s-cells and a mouse insulinoma cell line MIN6 with glucose stimulation results in an exocytotic reaction through membrane depolarization and an increase of intracellular Ca 2+ concentration ([Ca 2+ ] i ). To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc97522d56b3c0647596f9fdcae2220
https://doi.org/10.1016/s0003-2670(97)00705-8
https://doi.org/10.1016/s0003-2670(97)00705-8
Autor:
Yasufumi Fukano, Makoto Ito
Publikováno v:
Applied and Environmental Microbiology. 63:1861-1865
This paper describes the preparation of monosialoganglioside GM1 with sialidase-producing marine bacteria as a microbial biocatalyst. A new sialidase-producing bacterium, identified tentatively as Pseudomonas sp. strain YF-2, was isolated from seawat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1d4765d53610fe16d7bb628e5a2f3a
https://doi.org/10.1128/aem.63.5.1861-1865.1997
https://doi.org/10.1128/aem.63.5.1861-1865.1997
Autor:
Naohiro Tsuyama, Hajime Mizuno, Yasufumi Fukano, Mikihisa Takano, Tsutomu Masujima, Sachiko Date
Publikováno v:
Nanomedicine (London, England). 7(9)
Aim: We investigated the heterogeneity of tafluprost metabolism in primary human hepatocytes at a single-cell level by live single-cell mass spectrometry (MS). Materials & methods: Picoliter volumes of cytoplasm were analyzed by nano-electrospray ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e329b9e72be7022b61e74ee126e25344
https://pubmed.ncbi.nlm.nih.gov/22583577
https://pubmed.ncbi.nlm.nih.gov/22583577
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 27(3)
To investigate the metabolism of a new antiglaucoma difluoroprostaglandin, tafluprost, in ocular tissues and evaluate the distribution of the parent drug and its metabolites in ocular and systemic tissues after a single ocular administration to cynom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6096182a3290ab82c7381125b8316b9
https://pubmed.ncbi.nlm.nih.gov/21491995
https://pubmed.ncbi.nlm.nih.gov/21491995
Autor:
Kouichi Kawazu, Yasufumi Fukano
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 37(8)
The disposition and metabolism of tafluprost, an ester prodrug of the 15,15-difluoro-prostaglandin F(2alpha) antiglaucoma agent, have been studied in rats after ocular administration. Radioactivity was absorbed very rapidly into the eye and systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf8a954c2f9e67a5ac8bbaf597ab3f1
https://pubmed.ncbi.nlm.nih.gov/19477946
https://pubmed.ncbi.nlm.nih.gov/19477946