Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Yasue Matsuzawa"'
Autor:
Toshikazu Oki, Tomio Takeuchi, Hamao Umezawa, Akihiro Yoshimoto, Yasue Matsuzawa, Hiroshi Naganawa
Publikováno v:
The Journal of Antibiotics. 33:1150-1157
New anthracycline antibiotics, 1-hydroxy-13-dihydrodaunomycin and N-formyl-1-hydroxy-13-dihydrodaunomycin were biosynthesized by a blocked mutant of Streptomyces coeruleorubidus ME130-A4 from epsilon-pyrromycinone or epsilon-isorhodomycinone.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da4fee48ff1640c504f989d2454059b
https://doi.org/10.7164/antibiotics.33.1150
https://doi.org/10.7164/antibiotics.33.1150
Autor:
Tomio Takeuchi, Senji Hori, Masa Hamada, Akira Takamatsu, Yasue Matsuzawa, Masaaki Shizuka, Hamao Umezawa, Akihiro Yoshimoto, Hiroshi Tone, Toshikazu Oki
Publikováno v:
The Journal of Antibiotics. 28:479-482
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0405260a431089d669bd2a4ed6da02
https://doi.org/10.7164/antibiotics.28.479
https://doi.org/10.7164/antibiotics.28.479
Autor:
Taiji Inui, Toshikazu Oki, Takeo Yoshioka, Yasue Matsuzawa, Yasutaka Shimauchi, Hiroshi Tanaka
Publikováno v:
The Journal of Antibiotics. 33:1323-1330
Demethoxycarbonyl derivatives of aclacinomycin A and of its 7-epimer, 10-epi-aclacinomycin A and 4-O-methylaclacinomycin A were chemically derived from aclacinomycin A. The cytotoxicity and inhibitory effects of RNA and DNA synthesis in cultured L121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84d5a2c1b715dad93b0abb9b9b455c9
https://doi.org/10.7164/antibiotics.33.1323
https://doi.org/10.7164/antibiotics.33.1323
Autor:
Tomoyuki Ishikura, Yasue Matsuzawa, Toshio Kiyosaki, Tomio Takeuchi, Hamao Umezawa, Akihiro Yoshimoto
Publikováno v:
Journal of Pharmacobio-Dynamics. 5:886-892
Aclacinomycin A (ACM) antisera were abtained from the rabbits immunized with 4'''-deoxo-4'''-(R)-amino-ACM-or N, N-didemethyl-ACM-bovine serum albumin conjugate, and their immunoreactivites were tested with ACM-related anthracyclines. It was found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6a219b5dfad481c3adb6647ddba093
https://doi.org/10.1248/bpb1978.5.886
https://doi.org/10.1248/bpb1978.5.886
Autor:
Yasue Matsuzawa, Tomio Takeuchi, Hiroshi Naganawa, Toshikazu Oki, Hamao Umezawa, Akihiro Yoshimoto, Kohki Kiyoshima
Publikováno v:
The Journal of Antibiotics. 34:783-790
Various blocked mutants were isolated from Streptomyces coendeorubidus ME130-A4 by NTG and UV treatments. Among them, mutant strain 4N-140 produced new anthracycline feudomycins A and B having new aglycones in which the side chain at C-9 position of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf675ccd3d1a87ddf24222e3eb6685
https://doi.org/10.7164/antibiotics.34.783
https://doi.org/10.7164/antibiotics.34.783
Autor:
Hamao Umezawa, Akihiro Yoshimoto, Toshikazu Oki, Norio Shibamoto, Hiroshi Naganawa, Yasue Matsuzawa, Tomio Takeuchi, Hiroyasu Tobe
Publikováno v:
The Journal of Antibiotics. 34:959-964
Four blocked mutants of aclacinomycin-producing Streptomyces galilaeus MA144-M1 produced new anthracyclinones; 2-hydroxyaklavinone, its non-esterified analog and 2-hydroxy-7-deoxyaklavi none, several new anthracyclines; 2-deoxyfucosyl-2-deoxyfucosyl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edd9bfe8d1460ad2b90ad6cae2da28c
https://doi.org/10.7164/antibiotics.34.959
https://doi.org/10.7164/antibiotics.34.959
Autor:
Tomio Takeuchi, Toshikazu Oki, Iwao Kitamura, Hamao Umezawa, Masaaki Ishizuka, Akihiro Yoshimoto, Akira Takamatsu, Kenji Numata, Hiroshi Naganawa, Masa Hamada, Senji Hori, Yasue Matsuzawa, Hiroyuki Suda
Publikováno v:
The Journal of Antibiotics. 28:830-834
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bbd95e097a0bdef0b41a656bcc8336
https://doi.org/10.7164/antibiotics.28.830
https://doi.org/10.7164/antibiotics.28.830
Autor:
Akira Takamatsu, Toru Masuda, Yasue Matsuzawa, Tatsuo Ogasawara, Hamao Umezawa, Akihiro Yoshimoto, Tomio Takeuchi, Masa Hamada, Tsutomu Sawa, Masaaki Ishizuka, Hiroyuki Suda, Norio Shibamoto, Taiji Inui, Iwao Kitamura, Toshikazu Oki
Publikováno v:
The Journal of Antibiotics. 32:791-800
Aclacinomycin A and B, two major components of a new antitumor antibiotic complex, and their 19 analogues were produced by a culture of strain No. MA144-M1, which was identified as Streptomyces galilaeus. They were isolated by chelation with copper i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6560f278ef600c377f02c94fcef9441
https://doi.org/10.7164/antibiotics.32.791
https://doi.org/10.7164/antibiotics.32.791
Autor:
Takeo Yoshioka, Yasue Matsuzawa, Yasutaka Shimauchi, Taiji Inui, Hiroshi Tanaka, Toshikazu Oki, Yoshiyuki Matsushita
Publikováno v:
The Journal of Antibiotics. 34:905-908
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65a5331ef1bcfe33c18fb89c1febb41
https://doi.org/10.7164/antibiotics.34.905
https://doi.org/10.7164/antibiotics.34.905
Autor:
Taiji Inui, Toshikazu Oki, Hiroshi Naganawa, Tomio Takeuchi, Norio Shibamoto, Iwao Kitamura, Yasue Matsuzawa, Hamao Umezawa, Akihiro Yoshimoto, Tatsuo Ogasawara
Publikováno v:
The Journal of Antibiotics. 32:801-819
The structures of aclacinomycins A and B and 19 analogues were determined by a combination of chemical conversions and degradations and spectral interpretations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467b615e417c590967dda882607a8e6b
https://doi.org/10.7164/antibiotics.32.801
https://doi.org/10.7164/antibiotics.32.801