Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yasuaki UEMATSU"'
Autor:
Miki HORI, Yasuaki UEMATSU, Akiko KATO, Tadasuke HORI, Hironao SEKINE, Yuzo OHNO, Tatsushi KAWAI
Publikováno v:
Dental Materials Journal; 2023, Vol. 42 Issue 5, p723-731, 9p
Autor:
Tatsuhide Hayashi, Masaki Asakura, Mayu Kawase, Masakazu Matsubara, Yasuaki Uematsu, Akimichi Mieki, Tatsushi Kawai
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 6927
This study aimed to induce bone-like tissue from immature muscular tissue (IMT) in vitro using commercially available recombinant human bone morphogenetic protein (rhBMP)-2, rhBMP-4, and rhBMP-7, and then implanting this tissue into a calvarial defec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a63f2621de499ac523038a47055bb4
https://pubmed.ncbi.nlm.nih.gov/35805943
https://pubmed.ncbi.nlm.nih.gov/35805943
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 811:35-42
To evaluate the suitability of the rat Pig-a assay on reticulocytes (PIGRET assay) as a short-term test, red blood cell (RBC) Pig-a and PIGRET assays after single doses with hydroxyurea (HU) and melphalan (L-PAM) were conducted and the results of bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c4d4eb47ef24fc0c551fc3a8d1d9f
https://doi.org/10.1016/j.mrgentox.2016.06.003
https://doi.org/10.1016/j.mrgentox.2016.06.003
Autor:
Hideki Adachi, Yoshifumi Uno, Yuki Okada, Kunio Wada, Yosuke Ogiwara, Shigeharu Muto, Katsuyoshi Horibata, Shuichi Hamada, Mika Yamamoto, Akihisa Maeda, Eri Tsutsumi, Masami Yamada, Yasuaki Uematsu, Hironao Takasawa, Masamitsu Honma, Takeshi Morita, Ikuma Yoshida, Satoru Itoh, Hisako Hori, Shiho Nakayama, Hisakazu Sanada, Akiko Ukai, Miyuki Shigano, Kazunori Narumi, Naomi Koyama, Takafumi Kimoto, Yuta Suzuki, Daishiro Miura, Takayuki Fukuda, Yohei Fujiishi, Ken Goto, Satsuki Chikura, Ryuta Kikuzuki, Takahiro Kyoya
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 811:3-15
The in vivo mutation assay using the X-linked phosphatidylinositol glycan class A gene (Pig-a in rodents, PIG-A in humans) is a promising tool for evaluating the mutagenicity of chemicals. Approaches for measuring Pig-a mutant cells have focused on p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece3a3f5c327f782fb31dcbf00bbf454
Publikováno v:
Toxicology and Applied Pharmacology. 307:1-9
MicroRNA (miRNA) is a class of small non-coding RNAs containing approximately 20 nucleotides that negatively regulate target gene expression. Little is known about the role of individual miRNAs and their targets in immune- and inflammation-related re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5de9231a0adce4657b3f5c69f823ae
https://doi.org/10.1016/j.taap.2016.07.008
https://doi.org/10.1016/j.taap.2016.07.008
Publikováno v:
Journal of Applied Toxicology. 36:702-715
Methimazole (MTZ), an anti-thyroid drug, is known to cause liver injury in humans. It has been demonstrated that MTZ-induced liver injury in Balb/c mice is accompanied by T helper (Th) 2 cytokine-mediated immune responses; however, there is little ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::827cb886969b746e21b6a21fb7cf14d8
https://doi.org/10.1002/jat.3202
https://doi.org/10.1002/jat.3202
Autor:
Yoshiharu Uruno, Atsushi Kitamura, Takeshi Enomoto, Akihiko Kiyoshi, Yoshiaki Ochi, Takaaki Sumiyoshi, Yasuko Konishi, Tomokazu Nakako, Atsushi Suwa, Harumi Matsuda, Kentaro Takai, Mutsuko Sakai, Yasuaki Uematsu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:2909-2912
We designed and synthesized novel N-sulfonyl-7-azaindoline derivatives as selective M4 muscarinic acetylcholine receptor agonists. Modification of the N-carbethoxy piperidine moiety of compound 2, an M4 muscarinic acetylcholine receptor (mAChR)-prefe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d8f2e8dcfab4fa60b40eac642c9174
https://doi.org/10.1016/j.bmcl.2014.04.083
https://doi.org/10.1016/j.bmcl.2014.04.083
Autor:
Tatsuhide Hayashi, Yasuaki Uematsu, Tatsushi Kawai, Atsuko Ueno, Mayu Kawase, Syuichiro Kobayashi, Masaki Asakura
Publikováno v:
Journal of Biomedical Materials Research Part A. 102:3112-3121
The objective of this study was to induce bone formation from immature muscular tissue (IMT) in vitro, using bone morphogenetic proteins (BMPs) as a cytokine source and an expanded polytetrafluoroethylene (ePTFE) scaffold. In addition, cultured IMTs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3ddcb7f8561ae9bdeaeba6942bbb13e
https://doi.org/10.1002/jbm.a.34971
https://doi.org/10.1002/jbm.a.34971
Autor:
Yoko Takahashi, Yasuaki Uematsu, Mutsuko Sakai, Atsushi Kitamura, Harumi Matsuda, Kentaro Takai, Akihiko Kiyoshi, Takaaki Sumiyoshi, Yasuko Konishi, Tomokazu Nakako, Kengo Tojo, Atsushi Suwa, Yoshiharu Uruno, Takeshi Enomoto
Publikováno v:
ACS Medicinal Chemistry Letters. 4:244-248
Activation of the M1 and M4 muscarinic acetylcholine receptors is thought to play an important role in improving the symptoms of schizophrenia. However, discovery of selective agonists for these receptors has been a challenge, considering the high se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b9ee88415a41c72fc7cd07dd6da120
https://doi.org/10.1021/ml300372f
https://doi.org/10.1021/ml300372f
Autor:
Kaori Miyata, Juki Kimura, Ryoko Matsuyama, Toru Yamada, Hitoshi Funabashi, Mika Ota, Koichi Saito, Keiko Ogata, Sachiko Kitamoto, Yasuaki Uematsu
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis.
As a part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of the in vivo alkaline comet assay (comet assay), we examined DNA damage in the liver, stomach, and bone marrow of rats dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dacf70002f7de98ad1dbc55b5237b8b
https://pubmed.ncbi.nlm.nih.gov/26212304
https://pubmed.ncbi.nlm.nih.gov/26212304