Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yasuaki Osada"'
Publikováno v:
Archives of Virology. 134:97-107
The pathogenesis of infection in mice with herpes simplex virus type 1 (HSV-1) strain 7401H was studied. Mice immunosuppressed by intraperitoneal injection of cyclophosphamide were inoculated cutaneously into the flank with the virus and developed se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8659442d8c32fdeb8cb8586c3f4821
https://doi.org/10.1007/bf01379110
https://doi.org/10.1007/bf01379110
Autor:
Yoichi Murakami, Keiichi Uchida, Toshiaki Nakayama, Yasuaki Osada, Shohgo Atarashi, Yoshitomi Morizawa, Yasushi Matsumura, Arata Yasuda, Hiroyuki Takase, Tohru Ikeuchi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 42:183-187
The synthesis and antiviral activity of racemic carbocyclic 2',3'-dideoxy-3'-fluoro nucleosides are reported. Carbocyclic 2',3'-dideoxy-3'-fluoro nucleosides were obtained from the 3-fluoro cyclopentane derivative 4, which was prepared by two methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4c08e48504d35b310b1031aa5d695c
https://doi.org/10.1248/cpb.42.183
https://doi.org/10.1248/cpb.42.183
Publikováno v:
AIDS. 8:43-48
OBJECTIVE To determine whether the anti-angiogenesis agent DS-4152 inhibits the replication of HIV-1 in vitro. DESIGN A sulfated polysaccharide-peptidoglycan DS-4152 has recently been identified as a potent and selective inhibitor of Kaposi's sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223eb3c5bd7bac4fb4bfac68e1e68d05
https://doi.org/10.1097/00002030-199401000-00007
https://doi.org/10.1097/00002030-199401000-00007
Publikováno v:
Journal of Cellular Physiology. 154:1-6
The effects of sulfated polysaccharides on the growth and chemotaxis of endothelial cells promoted by basic fibroblast growth factor (bFGF), a heparin-binding growth factor, and epidermal growth factor (EGF), a non-heparin-growth factor, were examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ab910714a98179da663c4edeca15cd
https://doi.org/10.1002/jcp.1041540102
https://doi.org/10.1002/jcp.1041540102
Autor:
Shohgo Atarashi, Tohru Ikeuchi, Yoshitomi Morizawa, Keiichi Uchida, Yoichi Murakami, Yasuaki Osada, Yasushi Matsumura, Toshiaki Nakayama, Arata Yasuda, Hiroyuki Takase
Publikováno v:
ChemInform. 25
The synthesis and antiviral activity of racemic carbocyclic 2', 3'-dideoxy-3'-fluoro nucleosides are reported. Carbocyclic 2', 3'-dideoxy-3'-fluoro nucleosides were obtained from the 3-fluoro cyclopentane derivative 4, which was prepared by two metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::824e1239d0ebd9e168988c5b1018c69d
https://doi.org/10.1002/chin.199437248
https://doi.org/10.1002/chin.199437248
Publikováno v:
Cancer Immunology Immunotherapy. 35:307-314
The antitumor effect of a synthetic lipid A analogue, DT-5461, was investigated using syngeneic tumor models in mice. Intravenous injection of DT-5461 into mice transplanted with solid tumors of MethA fibrosarcoma, MH134 hepatoma, MM46 mammary carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012280fa3cff3cccd37079dcf74e9bab
https://doi.org/10.1007/bf01741143
https://doi.org/10.1007/bf01741143
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:1491-1498
DU-6859, (-)-7-[(7S)-amino-5-azaspiro(2,4)heptan-5-yl]-8-chloro-6- fluoro-1-[(1R,2R)-cis-2-fluoro-1-cyclopropyl]-1,4-dihydro-4-oxoquinol one-3- carboxylic acid, is a new fluoroquinolone with antibacterial activity which is significantly better than t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011aab29bfdabf9bfbe12c9b40091bc6
https://doi.org/10.1128/aac.36.7.1491
https://doi.org/10.1128/aac.36.7.1491
Publikováno v:
Blood. 83(9)
The response of megakaryocytes and platelets to the administration of romurtide, a synthetic muramyl dipeptide derivative, was investigated in normal and irradiated guinea pigs. Romurtide was administered subcutaneously in a single dose or daily dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4d85ac20eabe3f89759e1ff5fd5619
https://pubmed.ncbi.nlm.nih.gov/8167336
https://pubmed.ncbi.nlm.nih.gov/8167336
We compared the in vitro antibacterial activity of DV-7751a against gram-positive and -negative bacteria with those of quinolones currently available. MICs for 90% of the strains tested (MIC90s) against clinical isolates of methicillin-susceptible an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a00f2742649463a468a12f69d0607d3
https://europepmc.org/articles/PMC192237/
https://europepmc.org/articles/PMC192237/
Publikováno v:
International journal of immunopharmacology. 15(6)
The ability of DT-5461, a chemically synthetic low-toxic lipid A analogue, to activate anti-Salmonella activity in C3H/HeN mice was examined. Previous intraperitoneal (i.p.) injection of DT-5461 (100 micrograms or more/mouse) significantly hindered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9556cb58c3f29301ed17b5ea98ea0ee
https://pubmed.ncbi.nlm.nih.gov/8407050
https://pubmed.ncbi.nlm.nih.gov/8407050