Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yasuaki Mino"'
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-9 (2020)
Abstract Background Itraconazole (ITZ), a triazole antifungal agent, is metabolized to hydroxy-ITZ (OH-ITZ), keto-ITZ (KT-ITZ), and N-desalkyl ITZ (ND-ITZ) by cytochrome P450 3A4. The pharmacokinetics of ND-ITZ remain largely unknown due to the lack
Externí odkaz:
https://doaj.org/article/17fc0c7fe7ab482aadd8ed7a13b41e75
Autor:
Shunta Akutsu, Yasuaki Mino, Takafumi Naito, Kohei Hoshikawa, Masao Saotome, Yuichiro Maekawa, Junichi Kawakami
Publikováno v:
European Journal of Clinical Pharmacology. 78:1311-1320
The diuretic effect of tolvaptan is largely blood level-dependent although it does exhibit interindividual differences according to cytochrome P450 (CYP) 3A5 genotype. This study aimed to investigate the pharmacokinetic relationship between plasma to
Autor:
Hiroshi Ikeda, Yasuaki Mino, Yasushi Takahashi, Yasutaka Iguchi, Daisuke Iguchi, Koji Fujita, Kazuki Ocho
Publikováno v:
Nihon Toseki Igakkai Zasshi. 55:467-473
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-9 (2020)
Journal of Pharmaceutical Health Care and Sciences
Journal of Pharmaceutical Health Care and Sciences
Background Itraconazole (ITZ), a triazole antifungal agent, is metabolized to hydroxy-ITZ (OH-ITZ), keto-ITZ (KT-ITZ), and N-desalkyl ITZ (ND-ITZ) by cytochrome P450 3A4. The pharmacokinetics of ND-ITZ remain largely unknown due to the lack of an acc
Publikováno v:
Journal of Infection and Chemotherapy. 25:1019-1025
Flavin-containing monooxygenase (FMO) 3 together with cytochrome P450 (CYP) 2C19 play a significant role in voriconazole N-oxidation. This study aimed to evaluate the influence of FMO3 and CYP2C19 genotypes on the plasma disposition and adverse effec
Publikováno v:
Pharmacy Practice (1886-3655); Oct-Dec2022, Vol. 20 Issue 4, p1-4, 4p
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 54:490-494
Background Mycophenolate mofetil has recently been reported to be effective against systemic lupus erythematosus. The influence of the pharmacokinetics of mycophenolic acid, the active form of mycophenolate mofetil and the major inactive mycophenolic
Autor:
Yasuaki Mino
Publikováno v:
YAKUGAKU ZASSHI. 135:1123-1127
Mycophenolate mofetil (MMF) has recently been reported to be effective in the treatment of systemic lupus erythematosus (SLE). The therapeutic range of mycophenolic acid (MPA) and its 7-O-glucuronide (MPAG), and factors affecting their pharmacokineti
Publikováno v:
Clinica Chimica Acta. 441:127-132
Background The expression of hepatic CYP3A decreases with inflammatory response but increases with glucocorticoid administration. The aim of this study was to evaluate the plasma concentration of voriconazole and itraconazole under inflammatory condi
Publikováno v:
Biological & Pharmaceutical Bulletin. 38:1496-1503
Metabolic saturation of voriconazole based on the trough plasma concentrations of voriconazole and its major metabolite N-oxide were evaluated according to CYP2C19 genotypes in 58 Japanese patients receiving voriconazole (median dose; 200 mg twice da