Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yasuaki Matsushita"'
Autor:
Takahiro Oguma, Chiaki Kuriyama, Keiko Nakayama, Yasuaki Matsushita, Kumiko Hikida, Minoru Tsuda-Tsukimoto, Akira Saito, Kenji Arakawa, Kiichiro Ueta, Masabumi Minami, Masaharu Shiotani
Publikováno v:
Journal of Pharmacological Sciences, Vol 132, Iss 4, Pp 255-261 (2016)
We investigated whether structurally different sodium–glucose cotransporter (SGLT) 2 inhibitors, when co-administered with dipeptidyl peptidase-4 (DPP4) inhibitors, could enhance glucagon-like peptide-1 (GLP-1) secretion during oral glucose toleran
Externí odkaz:
https://doaj.org/article/78a15480dadc48cda92be98d11ee68cc
Autor:
Takahiro Oguma, Chiaki Kuriyama, Keiko Nakayama, Yasuaki Matsushita, Kumiko Yoshida, Satoko Kiuchi, Yuka Ikenaga, Yoshinobu Nakamaru, Kumiko Hikida, Akira Saito, Kenji Arakawa, Kozo Oka, Kiichiro Ueta, Masaharu Shiotani
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 4, Pp 456-461 (2015)
To assess the impact of concomitant inhibition of sodium-glucose cotransporter (SGLT) 2 and dipeptidyl peptidase IV (DPP4) for the treatment of type 2 diabetes mellitus (T2DM), the effect of combined treatment with canagliflozin, a novel SGLT2 inhibi
Externí odkaz:
https://doaj.org/article/a6e709c959c5400b8377221d633d3134
Autor:
Yin Liang, Kenji Arakawa, Kiichiro Ueta, Yasuaki Matsushita, Chiaki Kuriyama, Tonya Martin, Fuyong Du, Yi Liu, June Xu, Bruce Conway, Jamie Conway, David Polidori, Kirk Ways, Keith Demarest
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30555 (2012)
BACKGROUND: Canagliflozin is a sodium glucose co-transporter (SGLT) 2 inhibitor in clinical development for the treatment of type 2 diabetes mellitus (T2DM). METHODS: (14)C-alpha-methylglucoside uptake in Chinese hamster ovary-K cells expressing huma
Externí odkaz:
https://doaj.org/article/df414787d96e4b259c141d5ae76d36f9
Autor:
Yasuaki Matsushita
Publikováno v:
Journal of The Surface Finishing Society of Japan. 69:296-300
Autor:
Yuichi Koga, Kiichiro Ueta, Eiji Kawanishi, Chiaki Kuriyama, Yasuaki Matsushita, Sumihiro Nomura, Shigeki Sakamaki, Yasuo Yamamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 61:1037-1043
The synthesis and structure-activity relationship (SAR) of thiophene-C-glucosides have been explored, and the human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitory activities and rat urinary glucose excretion (UGE) effects of 3a-f were e
Autor:
Sohichiro Nakamura, Takeyoshi Kano, Koichi Kawamura, Mitsuhiro Fujita, Takehiro Kasahara, Yasuaki Matsushita, Inoue Masaaki
Publikováno v:
Polymer. 51:4562-4570
A facile approach to the fabrication of ultrathin polymer films on a flat or curved substrate is presented. Polymers with unsaturated pendant groups were spin-coated on a photoinitiator tethered surface, which was then photoirradiated and washed with
Autor:
Keigo, Kameda, Yasuaki, Matsushita
Publikováno v:
Working papers series. Working paper. 40:1-19
Publikováno v:
Macromolecules. 40:7721-7726
Autor:
Kumiko Yoshida, Kenji Arakawa, Masaharu Shiotani, Minoru Tsuda-Tsukimoto, Chiaki Kuriyama, Kiichiro Ueta, Naoyuki Obokata, Keiko Nakayama, Yasuaki Matsushita, Akira Saito, Takahiro Oguma, Kumiko Hikida
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 354(3)
The sodium glucose cotransporter (SGLT) 1 plays a major role in glucose absorption and incretin hormone release in the gastrointestinal tract; however, the impact of SGLT1 inhibition on plasma glucagon-like peptide-1 (GLP-1) levels in vivo is controv
Autor:
Masaharu Shiotani, Morihiro Matsuda, Yasuaki Matsushita, Shigetada Furukawa, Takuya Fujita, Tomomi Ishihara, Kentaro Morita, Iichiro Shimomura
Publikováno v:
Biochemical and Biophysical Research Communications. 328:369-374
Hyperglycemia-induced activation of hexosamine biosynthesis pathway (HBP) has been implicated in the development of insulin resistance in skeletal muscles. In the present study, the content of uridine-5'-diphospho-N-acetylglucosamine, the end product