Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Yasu-Taka Azuma"'
Autor:
Kohei Ariyoshi, Kazuhiro Nishiyama, Yuri Kato, Xinya Mi, Tomoya Ito, Yasu-Taka Azuma, Akiyuki Nishimura, Motohiro Nishida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5446 (2024)
Lipid droplet (LD) accumulation in hepatocytes is one of the major symptoms associated with fatty liver disease. Mitochondria play a key role in catabolizing fatty acids for energy production through β-oxidation. The interplay between mitochondria a
Externí odkaz:
https://doaj.org/article/2254d0038ed846148b2a44998bbc1dfd
Autor:
Kazuhiro Nishiyama, Yuri Kato, Akiyuki Nishimura, Xinya Mi, Ryu Nagata, Yasuo Mori, Yasu-Taka Azuma, Motohiro Nishida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2401 (2024)
We recently reported that transient receptor potential canonical (TRPC) 6 channel activity contributes to intracellular Zn2+ homeostasis in the heart. Zn2+ has also been implicated in the regulation of intestinal redox and microbial homeostasis. This
Externí odkaz:
https://doaj.org/article/27068aed373a425fb0f8a4f9abff5cc3
Autor:
Naoshige Ono, Takashi Fujita, Mariko Miki, Kazuhiro Nishiyama, Takeshi Izawa, Tomoko Aoyama, Mitsuru Kuwamura, Hideki Fujii, Yasu-Taka Azuma
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2064 (2023)
IL-19 is a cytokine discovered by homologous searching with IL-10 and is produced by non-immune cells, such as keratinocytes, in addition to immune cells, such as macrophages. Liver fibrosis results from the inflammation and activation of hepatic ste
Externí odkaz:
https://doaj.org/article/0762a9cd455949bd85adecfa121e2d8f
Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis
Autor:
Hiroyasu Komiya, Hideyuki Takeuchi, Yuki Ogawa, Kosuke Suzuki, Akihiro Ogasawara, Keita Takahashi, Yasu-Taka Azuma, Hiroshi Doi, Fumiaki Tanaka
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Neuroinflammation by activated microglia and astrocytes plays a critical role in progression of amyotrophic lateral sclerosis (ALS). Interleukin-19 (IL-19) is a negative-feedback regulator that limits pro-inflammatory responses of microglia
Externí odkaz:
https://doaj.org/article/dde5e4315cde4b39a8c64ec8c2df5d34
Autor:
Hiroshi Horiuchi, Bijay Parajuli, Hiroyasu Komiya, Yuki Ogawa, Shijie Jin, Keita Takahashi, Yasu-Taka Azuma, Fumiaki Tanaka, Akio Suzumura, Hideyuki Takeuchi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interleukin-19 (IL-19) acts as a negative-feedback regulator to limit proinflammatory response of macrophages and microglia in autocrine/paracrine manners in various inflammatory diseases. Multiple sclerosis (MS) is a major neuroinflammatory disease
Externí odkaz:
https://doaj.org/article/57c9d2ddd4074d8c9c7364a5c66518bb
Autor:
Yasu-Taka Azuma, Takashi Fujita, Takeshi Izawa, Kana Hirota, Kazuhiro Nishiyama, Airi Ikegami, Tomoko Aoyama, Mikihito Ike, Yumi Ushikai, Mitsuru Kuwamura, Hideki Fujii, Koichi Tsuneyama
Publikováno v:
Cells, Vol 10, Iss 12, p 3513 (2021)
Interleukin (IL)-19, a member of the IL-10 family, is an anti-inflammatory cytokine produced primarily by macrophages. Nonalcoholic steatohepatitis (NASH) is a disease that has progressed from nonalcoholic fatty liver disease (NAFLD) and is character
Externí odkaz:
https://doaj.org/article/473f955a8b6547389d1442ab0e570335
Autor:
Yasuyuki Fujimoto, Satomi Hayashi, Yasu-Taka Azuma, Kazunori Mukai, Kazuhiro Nishiyama, Satomi Kita, Ai Morioka, Hidemitsu Nakajima, Takahiro Iwamoto, Tadayoshi Takeuchi
Publikováno v:
Journal of Pharmacological Sciences, Vol 132, Iss 3, Pp 181-186 (2016)
In gastric smooth muscles, the released Ca2+ activates the contractile proteins and Ca2+ taken up from the cytosol cause relaxation. The Na+/Ca2+ exchanger (NCX) is an antiporter membrane protein that controls Ca2+ influx and efflux across the membra
Externí odkaz:
https://doaj.org/article/ba362392ed9041958d91ae56a3c63b35
Autor:
Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J. H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean-Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu-Taka Azuma, Laura Cerchia, Mariana Spetea, Giangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A. R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A. C. Gomes, Rita C. Guedes, Jean-Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 25, Iss 13, p 2968 (2020)
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Externí odkaz:
https://doaj.org/article/d1b45d5624194ce7bc35f0b2a26b0ee6
Autor:
Chika Natsume, Nao Aoki, Tomoko Aoyama, Keisuke Senda, Mio Matsui, Airi Ikegami, Kosuke Tanaka, Yasu-Taka Azuma, Takashi Fujita
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2180 (2020)
Fucoxanthin (FX) is a xanthophyll that is contained abundantly in marine plants. The biological action of FX includes its antioxidant and anti-lipogenic activities, while the precise action of its mechanisms on skin cells has not yet been clarified.
Externí odkaz:
https://doaj.org/article/2931d9749c804113b664484683b72be1
Autor:
Jean Jacques Vanden Eynde, Arduino A. Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T. García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A. C. Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Laura Cerchia, Jean-Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, F. Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, M. Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília de Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdiero, Hong Liu, Peter J. H. Scott, Cristóbal de los Ríos, Luigi A. Agrofoglio, Simona Collina, Rita C. Guedes, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 25, Iss 1, p 119 (2019)
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials that is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Externí odkaz:
https://doaj.org/article/3cd6ccb2d2144bde8974e0647ecc5397