Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yassine Rechoum"'
Autor:
Sandra L. Grimm, Guowei Gu, Sarah K. Herzog, Thomas L. Gonzalez, Hangqing Lin, Amanda R. Beyer, Yassine Rechoum, Tasneem Bawa-Khalfe, Ashfia F. Khan, Lili Du, W. Fraser Symmans, Ralf Kittler, Cristian Coarfa, Suzanne A.W. Fuqua
Publikováno v:
Cancer Research. 82:PD1-07
Background: Acquired ESR1 mutations are a dominant driver of distant metastasis in metastatic breast cancer, inducing a basal-like phenotype that is relatively resistant to ER antagonists with decreased progression free survival. The majority of ER+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943b176fbd5f57b73ecf1d90e7f894aa
https://doi.org/10.1158/1538-7445.sabcs21-pd1-07
https://doi.org/10.1158/1538-7445.sabcs21-pd1-07
Autor:
Yassine Rechoum, Jin-Ah Kim, Shunqiang Li, Sarah Herzog, Filip Janku, David Edwards, Gordon B. Mills, Helen J. Huang, W. Fraser Symmans, Charles E. Foulds, Luca Gelsomino, Suzanne A. W. Fuqua, Cristian Coarfa, Sandra L. Grimm, Lili Du, Meng Gao, Xiang Zhang, Susan G. Hilsenbeck, Hin Ching Lo, Sebastiano Andò, Thomas Gonzalez, Lin Tian, Alyssa Alaniz, Amanda Beyer, Guowei Gu, Dan Liu, Derek Dustin, Anna Tsimelzon, Natalie M. Fernandez, Jun Xu, Ralf Kittler
Publikováno v:
Oncogene
Estrogen receptor alpha gene (ESR1) mutations occur frequently in ER-positive metastatic breast cancer (MBC), and confer clinical resistance to aromatase inhibitors (AIs). Expression of the ESR1 Y537S mutation induced an epithelial-mesenchymal transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35a636238c069b7d49bd5fb192f55e0
https://pubmed.ncbi.nlm.nih.gov/34782721
https://pubmed.ncbi.nlm.nih.gov/34782721
Autor:
Meng Gao, Hin Ching Lo, Shunqiang Li, David Edwards, W. Fraser Symmans, Gordon B. Mills, Cristian Coarfa, Guowei Gu, Charles E. Foulds, Dan Liu, Alyssa Alaniz, Amanda Beyer, Sandra L. Grimm, Derek Dustin, Lili Du, Lin Tian, Anna Tsimelzon, Jin-Ah Kim, Helen J. Huang, Ralf Kittler, Sebastiano Andò, Susan G. Hilsenbeck, Luca Gelsomino, Suzanne A. W. Fuqua, Xiang Zhang, Jun Xu, Natalie M. Fernandez, Thomas Gonzalez, Yassine Rechoum, Sarah Herzog, Filip Janku
Publikováno v:
Oncogene. 41:460-460
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ce004ed5a6b939af17cea0a0944647
https://doi.org/10.1038/s41388-021-02104-w
https://doi.org/10.1038/s41388-021-02104-w
Autor:
Thomas L. Gonzalez, Yassine Rechoum, Cristian Coarfa, Sarah Herzog, David Edwards, Hangqing Lin, Tasneem Bawa-Khalfe, Nancy L. Weigel, Sandra L. Grimm, Suzanne A. W. Fuqua, Amanda Beyer, Guowei Gu, Basil Paul, Ralf Kittler
Publikováno v:
Cancer Research. 81:PD8-09
Background: Recurrences are delayed for years with endocrine therapy (ET), but resistance ultimately evolves with the development of ER+ metastatic breast cancer (MBC). ESR1 mutations are acquired in MBC undergoing ET in about 20-40% of patients. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0428721074d8d44b45b5073d340f3411
https://doi.org/10.1158/1538-7445.sabcs20-pd8-09
https://doi.org/10.1158/1538-7445.sabcs20-pd8-09
Autor:
Kenneth E. Huffman, Suzanne A. W. Fuqua, Yassine Rechoum, Andrew T. Ludlow, Sasha M. Pejerrey, Anna Tsimelzon, Guowei Gu, Amanda Beyer, Sebastiano Andò, Luca Gelsomino, Tao Wang
Publikováno v:
Breast Cancer Res Treat
The purpose of this study was to address the role of ESR1 hormone-binding mutations in breast cancer. Soft agar anchorage-independent growth assay, Western blot, ERE reporter transactivation assay, proximity ligation assay (PLA), coimmunoprecipitatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c20351d77e1f139055bc1a7ff1de5ca
https://doi.org/10.1007/s10549-016-3829-5
https://doi.org/10.1007/s10549-016-3829-5
Autor:
Kyle R. Covington, Amanda Beyer, Yassine Rechoum, Ryan Carstens, John Wang, Suzanne A. W. Fuqua, Luca Gelsomino, Sebastiano Andò, Kenneth E. Huffman, Guowei Gu
Publikováno v:
Breast Cancer Research and Treatment. 150:535-545
The purpose of this study was to discover novel nuclear receptor targets in triple-negative breast cancer. Expression microarray, Western blot, qRT-PCR analyses, MTT growth assay, soft agar anchorage-independent growth assay, TRE reporter transactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93ff080e3d3634feda1a8c61296407f
https://doi.org/10.1007/s10549-015-3354-y
https://doi.org/10.1007/s10549-015-3354-y
Publikováno v:
Horm Cancer
After nearly 20 years of research, it is now established that mutations within the estrogen receptor (ER) gene, ESR1, frequently occur in metastatic breast cancer and influence response to hormone therapy. Though early studies presented differing res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514cc9f7b087ead1794aa2f41b47adf5
https://pubmed.ncbi.nlm.nih.gov/29736566
https://pubmed.ncbi.nlm.nih.gov/29736566
Autor:
Yassine Rechoum, Emmanuel Drouet, Frederic Garzoni, Pascal Fender, Olivier François, Alban Caporossi, Sylvie Larrat, Catherine Fallecker, Patrice Morand, Marie Anne Petit, Imre Berger
Publikováno v:
Virology Journal
Virology Journal, 2016, 14 (1), pp.161. ⟨10.1186/s12985-017-0828-z⟩
Virology Journal, BioMed Central, 2016, 14 (1), pp.161. ⟨10.1186/s12985-017-0828-z⟩
Virology Journal, BioMed Central, 2016, 14 (1), pp.161. 〈10.1186/s12985-017-0828-z〉
Fallecker, C, Caporossi, A, Rechoum, Y, Garzoni, F, Larrat, S, François, O, Fender, P, Morand, P, Berger, I, Petit, M A & Drouet, E 2017, ' New insights into HCV replication in original cells from Aedes mosquitoes ', Virology Journal, vol. 14, 161 . https://doi.org/10.1186/s12985-017-0828-z
Virology Journal, 2016, 14 (1), pp.161. ⟨10.1186/s12985-017-0828-z⟩
Virology Journal, BioMed Central, 2016, 14 (1), pp.161. ⟨10.1186/s12985-017-0828-z⟩
Virology Journal, BioMed Central, 2016, 14 (1), pp.161. 〈10.1186/s12985-017-0828-z〉
Fallecker, C, Caporossi, A, Rechoum, Y, Garzoni, F, Larrat, S, François, O, Fender, P, Morand, P, Berger, I, Petit, M A & Drouet, E 2017, ' New insights into HCV replication in original cells from Aedes mosquitoes ', Virology Journal, vol. 14, 161 . https://doi.org/10.1186/s12985-017-0828-z
Background The existing literature about HCV association with, and replication in mosquitoes is extremely poor. To fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of HCV E1E2 glycoproteins to bind on Aedes mosq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fc8350ede97b7b72219e81b8d17711
https://www.hal.inserm.fr/inserm-01577634/document
https://www.hal.inserm.fr/inserm-01577634/document
Autor:
John D. Minna, Yassine Rechoum, Kyle R. Covington, Guowei Gu, Bert W. O'Malley, David J. Mangelsdorf, Paul Webb, Suzanne A. W. Fuqua
Publikováno v:
Cancer Research. 72:P4-08
Background: The treatment of estrogen receptor (ER)-negative breast cancer (BC) is a major clinical problem due to the lack of useful therapeutic targets. Nuclear receptors (NRs) are potential targets in these patients because they regulate global tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee2b98cfee49105a5d014c26225d524
https://doi.org/10.1158/0008-5472.sabcs12-p4-08-09
https://doi.org/10.1158/0008-5472.sabcs12-p4-08-09