Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Yassine Amrani"'
Autor:
Marwa M. E. Mohamed, Yassine Amrani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6170 (2024)
Obese patients with asthma present with aggravated symptoms that are also harder to treat. Here, we used a mouse model of allergic asthma sensitised and challenged to house dust mite (HDM) extracts to determine whether high-fat-diet consumption would
Externí odkaz:
https://doaj.org/article/cd52604d2457443ab5e23c6c6d59c9da
Autor:
Nada Slama, Amina Abdellatif, Karima Bahria, Sara Gasmi, Maamar Khames, Abderrahmene Hadji, George Birkmayer, Mustapha Oumouna, Yassine Amrani, Karine Benachour
Publikováno v:
Cells, Vol 13, Iss 10, p 881 (2024)
Cigarette smoke is one of the main factors in Chronic Obstructive Pulmonary Disease (COPD), a respiratory syndrome marked by persistent respiratory symptoms and increasing airway obstruction. Perturbed NAD+/NADH levels may play a role in various dise
Externí odkaz:
https://doaj.org/article/fed1145e4c3b4bdc88bab86630afdc9d
Autor:
Abdulrahman Alzahrani, Jameel Hakeem, Michael Biddle, Fahad Alhadian, Aamir Hussain, Latifa Khalfaoui, Katy M. Roach, Omar Tliba, Peter Bradding, Yassine Amrani
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
The mechanisms underlying corticosteroid insensitivity in severe asthma have not been elucidated although some indirect clinical evidence points toward a role of mast cells. Here, we tested the hypothesis that mast cells can drive corticosteroid inse
Externí odkaz:
https://doaj.org/article/2d6cc5806c3343ea905d61faa697cb69
Autor:
Katy M. Roach, Amanda Sutcliffe, Laura Matthews, Gill Elliott, Chris Newby, Yassine Amrani, Peter Bradding
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with limited therapeutic options. KCa3.1 ion channels play a critical role in TGFβ1-dependent pro-fibrotic responses in human lung myofibroblasts. We aimed to de
Externí odkaz:
https://doaj.org/article/46976a4f4c0e44a38515a896ef024507
Autor:
Gautam Damera, Kirk M Druey, Philip R Cooper, Vera P Krymskaya, Roy J Soberman, Yassine Amrani, Toshinori Hoshi, Christopher E Brightling, Reynold A Panettieri
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28504 (2012)
In severe asthma, bronchodilator- and steroid-insensitive airflow obstruction develops through unknown mechanisms characterized by increased lung airway smooth muscle (ASM) mass and stiffness. We explored the role of a Regulator of G-protein Signalin
Externí odkaz:
https://doaj.org/article/de3e4fc546244df895c5429b8532ccfe
Publikováno v:
Free Radical Biology and Medicine. 185:97-119
The airway smooth muscle (ASM) surrounding the airways is dysfunctional in both asthma and chronic obstructive pulmonary disease (COPD), exhibiting; increased contraction, increased mass, increased inflammatory mediator release and decreased corticos
Publikováno v:
CODS - Journal of Dentistry; Jul-Dec2023, Vol. 15 Issue 2, p59-63, 5p
Autor:
Michael Biddle, Dawn T. Smallwood, E Castells, Peter Bradding, Katy M. Roach, Cathryn Weston, Yassine Amrani, Viona W. Bowman, Harvinder Virk, Jamie McCarthy, S. Mark Duffy
Publikováno v:
British Journal of Pharmacology. 178:2948-2962
BACKGROUND AND PURPOSE TGFβ1-mediated myofibroblast activation contributes to pathological fibrosis in many diseases including idiopathic pulmonary fibrosis (IPF), where myofibroblast resistance to oxidant-mediated apoptosis is also evident. We ther
Autor:
Abdulrahman, Alzahrani, Aamir, Hussain, Fahad, Alhadian, Jameel, Hakeem, Sana, Douaoui, Omar, Tliba, Peter, Bradding, Yassine, Amrani
Publikováno v:
Advances in experimental medicine and biology. 1303
The mechanisms driving corticosteroid insensitivity in asthma are still unclear although evidence points toward a potential role of lung mast cells. Indeed, a number of in vitro studies using various cell types showed that different mediators produce
Autor:
Aamir Hussain, Fahad Alhadian, Peter Bradding, Omar Tliba, Yassine Amrani, Abdulrahman Alzahrani, Jameel Hakeem, Sana Douaoui
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030630454
The mechanisms driving corticosteroid insensitivity in asthma are still unclear although evidence points toward a potential role of lung mast cells. Indeed, a number of in vitro studies using various cell types showed that different mediators produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1228dcc6f4009e6f9d0ef6306de8170a
https://doi.org/10.1007/978-3-030-63046-1_1
https://doi.org/10.1007/978-3-030-63046-1_1